Zobrazeno 1 - 10
of 688
pro vyhledávání: '"Best, Robert B."'
Autor:
Galvanetto, Nicola, Ivanović, Miloš T., Del Grosso, Simone A., Chowdhury, Aritra, Sottini, Andrea, Nettels, Daniel, Best, Robert B., Schuler, Benjamin
Biomolecular condensates form by phase separation of biological polymers. The cellular functions of the resulting membraneless organelles are closely linked to their physical properties over a wide range of length- and timescales: From the nanosecond
Externí odkaz:
http://arxiv.org/abs/2407.19202
Autor:
Watanabe, Fuga, Akimoto, Takuma, Best, Robert B., Lindorff-Larsen, Kresten, Metzler, Ralf, Yamamoto, Eiji
In living cells, intrinsically disordered proteins (IDPs), such as FUS and DDX4, undergo phase separation, forming biomolecular condensates. Using molecular dynamics simulations, we investigate their behavior in their respective homogenous droplets.
Externí odkaz:
http://arxiv.org/abs/2401.10438
Autor:
Okuno, Yusuke, Yoo, Janghyun, Schwieters, Charles D., Best, Robert B., Chung, Hoi Sung, Clore, G. Marius
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Aug . 118(34), 1-9.
Externí odkaz:
https://www.jstor.org/stable/27075496
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2020 Jun . 117(25), 14119-14126.
Externí odkaz:
https://www.jstor.org/stable/26934939
Autor:
Kührová, Petra, Best, Robert B., Bottaro, Sandro, Bussi, Giovanni, Šponer, Jiří, Otyepka, Michal, Banáš, Pavel
Publikováno v:
J. Chem. Theory Comput. 2016, 12 (9), pp 4534-4548
The computer-aided folding of biomolecules, particularly RNAs, is one of the most difficult challenges in computational structural biology. RNA tetraloops are fundamental RNA motifs playing key roles in RNA folding and RNA-RNA and RNA-protein interac
Externí odkaz:
http://arxiv.org/abs/1609.08276
Publikováno v:
Phys. Rev. Lett. 116, 068102 (2016)
Experiments measuring contact formation between a probe and quencher in disordered chains provide information on the fundamental dynamical timescales relevant to protein folding, but their interpretation usually relies on simplified one-dimensional (
Externí odkaz:
http://arxiv.org/abs/1507.02448
Publikováno v:
J. Chem. Phys. 141, 22D522 (2014)
In contrast to the well-known destabilization of globular proteins by high pressure, re- cent work has shown that pressure stabilizes the formation of isolated {\alpha}-helices. However all simulations to date have obtained a qualitatively opposite r
Externí odkaz:
http://arxiv.org/abs/1503.03716
Autor:
Tian, Pengfei, Steward, Annette, Kudva, Renuka, Su, Ting, Shilling, Patrick J., Nickson, Adrian A., Hollins, Jeffrey J., Beckmann, Roland, von Heijne, Gunnar, Clarke, Jane, Best, Robert B.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Nov . 115(48), E11284-E11293.
Externí odkaz:
https://www.jstor.org/stable/26564444