Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Bessie Meechoovet"'
Autor:
Bogdan Mateescu, Jennifer C. Jones, Roger P. Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T. Chiu, Robert J. Coffey, Saumya Das, Peter De Hoff, Andrew deMello, Crislyn D’Souza-Schorey, David Elashoff, Kiarash R. Eliato, Jeffrey L. Franklin, David J. Galas, Mark B. Gerstein, Ionita H. Ghiran, David B. Go, Stephen Gould, Tristan R. Grogan, James N. Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K. Jeppesen, Tijana Jovanovic-Talisman, Betty Y.S. Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R. Kitchen, Vaughan Knouse, Emily L. LaPlante, Carlito B. Lebrilla, L. James Lee, Kathleen M. Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L. Maddox, Kyle McCarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P. De Oliveira Junior, Michael E. Paulaitis, Tuan Anh Phu, Robert L. Raffai, Eduardo Reátegui, Matthew E. Roth, David A. Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K. Sood, Stavros Stavrakis, Alessandra Stürchler, Muneesh Tewari, Juan P. Tosar, Alexander K. Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C. Vickers, Lucia Vojtech, Wyatt N. Vreeland, Ceming Wang, Kai Wang, ZeYu Wang, Joshua A. Welsh, Kenneth W. Witwer, David T.W. Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikołaj P. Zaborowski, Chenguang Zhang, Qin Zhang, Angela M. Zivkovic, Louise C. Laurent
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104653- (2022)
Summary: The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013–2018), Phase 2 of the progr
Externí odkaz:
https://doaj.org/article/d72ed055b3ab4740b73e722d85b82959
Autor:
Eric Alsop, Bessie Meechoovet, Robert Kitchen, Thadryan Sweeney, Thomas G. Beach, Geidy E. Serrano, Elizabeth Hutchins, Ionita Ghiran, Rebecca Reiman, Michael Syring, Michael Hsieh, Amanda Courtright-Lim, Nedyalka Valkov, Timothy G. Whitsett, Jorge Rakela, Paul Pockros, Joel Rozowsky, Juan Gallego, Matthew J. Huentelman, Ravi Shah, Peter Nakaji, M. Yashar S. Kalani, Louise Laurent, Saumya Das, Kendall Van Keuren-Jensen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
One promising goal for utilizing the molecular information circulating in biofluids is the discovery of clinically useful biomarkers. Extracellular RNAs (exRNAs) are one of the most diverse classes of molecular cargo, easily assayed by sequencing and
Externí odkaz:
https://doaj.org/article/0babcdfa00aa4ff999b84801b2a32992
Autor:
Laura Bouchareychas, Phat Duong, Tuan Anh Phu, Eric Alsop, Bessie Meechoovet, Rebecca Reiman, Martin Ng, Ryo Yamamoto, Hiromitsu Nakauchi, Warren J. Gasper, Kendall Van Keuren-Jensen, Robert L. Raffai
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102847- (2021)
Summary: We investigated whether extracellular vesicles (EVs) produced under hyperglycemic conditions could communicate signaling to drive atherosclerosis. We did so by treating Apoe−/− mice with exosomes produced by bone marrow-derived macrophag
Externí odkaz:
https://doaj.org/article/02f07b8c814e4af2af690b9e36151767
Autor:
Adrienne R. Henderson, Qi Wang, Bessie Meechoovet, Ashley L. Siniard, Marcus Naymik, Matthew De Both, Matthew J. Huentelman, Richard J. Caselli, Erika Driver-Dunckley, Travis Dunckley
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease. It is presently only accurately diagnosed at an advanced stage by a series of motor deficits, which are predated by a litany of non-motor symptoms manifesting
Externí odkaz:
https://doaj.org/article/2d618f30f8de492a98d0be8ac1e9b9f9
Autor:
Laura Bouchareychas, Phat Duong, Sergio Covarrubias, Eric Alsop, Tuan Anh Phu, Allen Chung, Michael Gomes, David Wong, Bessie Meechoovet, Allyson Capili, Ryo Yamamoto, Hiromitsu Nakauchi, Michael T. McManus, Susan Carpenter, Kendall Van Keuren-Jensen, Robert L. Raffai
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107881- (2020)
Summary: Developing strategies that promote the resolution of vascular inflammation and atherosclerosis remains a major therapeutic challenge. Here, we show that exosomes produced by naive bone marrow-derived macrophages (BMDM-exo) contain anti-infla
Externí odkaz:
https://doaj.org/article/8eec14d6e9314bcca6dc8d52b7f5c412
Autor:
M. Yashar S. Kalani, Eric Alsop, Bessie Meechoovet, Taylor Beecroft, Komal Agrawal, Timothy G. Whitsett, Matthew J. Huentelman, Robert F. Spetzler, Peter Nakaji, Seungchan Kim, Kendall Van Keuren-Jensen
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Rapid identification of patients suffering from cerebral ischaemia, while excluding intracerebral haemorrhage, can assist with patient triage and expand patient access to chemical and mechanical revascularization. We sought to identify blood-based, e
Externí odkaz:
https://doaj.org/article/df28f35c2c89457d889a105785da6713
Autor:
Kathleen M. Lennon, Devin L. Wakefield, Adam L. Maddox, Matthew S. Brehove, Ari N. Willner, Krystine Garcia-Mansfield, Bessie Meechoovet, Rebecca Reiman, Elizabeth Hutchins, Marcia M. Miller, Ajay Goel, Patrick Pirrotte, Kendall Van Keuren-Jensen, Tijana Jovanovic-Talisman
Publikováno v:
Journal of Extracellular Vesicles, Vol 8, Iss 1 (2019)
Biofluid-accessible extracellular vesicles (EVs) may represent a new means to improve the sensitivity and specificity of detecting disease. However, current methods to isolate EVs encounter challenges when they are used to select specific populations
Externí odkaz:
https://doaj.org/article/364c6031b13846c3a8651fb570b8f5c3
Autor:
Adrienne Henderson-Smith, Donald Chow, Bessie Meechoovet, Meraj Aziz, Sandra A Jacobson, Holly A Shill, Marwan N Sabbagh, John N Caviness, Charles H Adler, Erika D Driver-Dunckley, Thomas G Beach, Hongwei Yin, Travis Dunckley
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77711 (2013)
Synucleinopathies are a broad class of neurodegenerative disorders characterized by the presence of intracellular protein aggregates containing α-synuclein protein. The aggregated α-synuclein protein is hyperphosphorylated on serine 129 (S129) comp
Externí odkaz:
https://doaj.org/article/0cbac269176e4118801e308c889d2f7d
Autor:
Danielle Frost, Bessie Meechoovet, Tong Wang, Stephen Gately, Marco Giorgetti, Irina Shcherbakova, Travis Dunckley
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19264 (2011)
Harmine, a β-carboline alkaloid, is a high affinity inhibitor of the dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) protein. The DYRK1A gene is located within the Down Syndrome Critical Region (DSCR) on chromosome 21. We and
Externí odkaz:
https://doaj.org/article/461050d70814499889e2fc7d3657b642
Autor:
Kaleen M. Lavin, Zachary A. Graham, Jeremy S. McAdam, Samia M. O’Bryan, Devin Drummer, Margaret B. Bell, Christian J. Kelley, Manoel E. Lixandrão, Brandon Peoples, S. Craig Tuggle, Regina S. Seay, Kendall Van Keuren-Jensen, Matthew J. Huentelman, Patrick Pirrotte, Rebecca Reiman, Eric Alsop, Elizabeth Hutchins, Jerry Antone, Anna Bonfitto, Bessie Meechoovet, Joanna Palade, Joshua S. Talboom, Amber Sullivan, Inmaculada Aban, Kalyani Peri, Timothy J. Broderick, Marcas M. Bamman
Publikováno v:
Physiological Genomics. 55:194-212
We examined small and long transcriptomics in skeletal muscle and serum-derived extracellular vesicles before and after a single exposure to traditional combined exercise (TRAD) and high-intensity tactical training (HITT). Across 40 young adults, we