Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Bessi Qorri"'
Autor:
Moses Cook, Bessi Qorri, Amruth Baskar, Jalal Ziauddin, Luca Pani, Shashibushan Yenkanchi, Joseph Geraci
Publikováno v:
Exploration of Medicine, Vol 4, Iss 4, Pp 428-440 (2023)
Aim: Many small datasets of significant value exist in the medical space that are being underutilized. Due to the heterogeneity of complex disorders found in oncology, systems capable of discovering patient subpopulations while elucidating etiologies
Externí odkaz:
https://doaj.org/article/dce635580c684506a07fbd6b5964fc05
Autor:
Joseph Geraci, Ravi Bhargava, Bessi Qorri, Paul Leonchyk, Douglas Cook, Moses Cook, Fanny Sie, Luca Pani
Publikováno v:
Frontiers in Computational Neuroscience, Vol 17 (2024)
IntroductionAdvances in machine learning (ML) methodologies, combined with multidisciplinary collaborations across biological and physical sciences, has the potential to propel drug discovery and development. Open Science fosters this collaboration b
Externí odkaz:
https://doaj.org/article/494d06c148a14fa2b70791f1ffcf836a
Publikováno v:
Cells, Vol 12, Iss 9, p 1332 (2023)
We discovered a novel therapeutic target critical for SARS-CoV-2, cellular infectivity and the induction of the cytokine release syndrome. Here, we show that the mammalian enzyme neuraminidase-1 (Neu-1) is part of a highly conserved signaling platfor
Externí odkaz:
https://doaj.org/article/ec6a093080f4491495b262426dc6a870
Publikováno v:
Exploration of Medicine, Vol 1, Iss 6, Pp 377-395 (2020)
Aim: Research suggests that Alzheimer’s disease (AD) is heterogeneous with numerous subtypes. Through a proprietary interactive ML system, several underlying biological mechanisms associated with AD pathology were uncovered. This paper is an introd
Externí odkaz:
https://doaj.org/article/4d862ac3f15f4b30aacced54c6ff7bf5
Publikováno v:
Nutrients, Vol 11, Iss 3, p 644 (2019)
Individuals widely use non-nutritive sweeteners (NNS) in attempts to lower their overall daily caloric intake, lose weight, and sustain a healthy diet. There are insufficient scientific data that support the safety of consuming NNS. However, recent s
Externí odkaz:
https://doaj.org/article/8a66f86d1ecb434caca3d9ed0dc05680
Autor:
Bessi Qorri, Regina-Veronicka Kalaydina, Aleksandra Velickovic, Yekatrina Kaplya, Alexandria Decarlo, Myron R. Szewczuk
Publikováno v:
Cells, Vol 7, Iss 9, p 117 (2018)
The extracellular matrix (ECM) is a highly dynamic noncellular structure that is crucial for maintaining tissue architecture and homeostasis. The dynamic nature of the ECM undergoes constant remodeling in response to stressors, tissue needs, and bioc
Externí odkaz:
https://doaj.org/article/60b5fdfb326541daab7f790035532aef
Autor:
Iryna Liauchonak, Fady Dawoud, Yatin Riat, Bessi Qorri, Manpreet Sambi, Justin Jain, Regina-Veronicka Kalaydina, Nicole Mendonza, Komal Bajwa, Myron R. Szewczuk
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 575 (2018)
Insulin signaling, as mediated through the insulin receptor (IR), plays a critical role in metabolism. Aberrations in this signaling cascade lead to several pathologies, the majority of which are classified under the umbrella term “metabolic syndro
Externí odkaz:
https://doaj.org/article/943b251104fe43b3831965edba72559f
Publikováno v:
Cancers; Volume 14; Issue 6; Pages: 1374
Resistance to chemotherapeutics and high metastatic rates contribute to the abysmal survival rate in patients with pancreatic cancer. An alternate approach for treating human pancreatic cancer involves repurposing the anti-inflammatory drug, aspirin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41eba1d181398598253cad043f19f11b
Autor:
Bessi Qorri, Vanessa Samuel, Manpreet Sambi, Myron R. Szewczuk, William Harless, Elena Markvicheva, Sergey V. Burov, Sabah Haq
Publikováno v:
Drug Design, Development and Therapy
Manpreet Sambi,1 Vanessa Samuel,1,2 Bessi Qorri,1 Sabah Haq,1,3 Sergey V Burov,4 Elena Markvicheva,5 William Harless,6 Myron R Szewczuk1 1Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, ON, Canada; 2Faculty of Medicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63fdd009e98c995863a0c3b9de55050
https://doi.org/10.2147/dddt.s242514
https://doi.org/10.2147/dddt.s242514
Autor:
Hai-Ling Margaret Cheng, Herman Yeger, Manpreet Sambi, Bikul Das, Sushil Kumar, Myron R. Szewczuk, Reza Bayat Mokhtari, Bessi Qorri, Neda Ashayeri, Narges Baluch
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3596, p 3596 (2021)
Cancers, Vol 13, Iss 3596, p 3596 (2021)
Simple Summary Drug development and therapeutic approaches for treating cancer have shifted towards incorporating more multimodality approaches that harness the immune system. Despite innovative and notable advances in immunotherapy, challenges assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d72dbf3f3917fbdd885b040b6daa167
https://pubmed.ncbi.nlm.nih.gov/34298809
https://pubmed.ncbi.nlm.nih.gov/34298809