Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making

Autor: Paini, A., Leonard, J. A., Joossens, E., Bessems, J. G.M., Desalegn, A., Dorne, J. L., Gosling, J. P., Heringa, M. B., Klaric, M., Kliment, T., Kramer, N. I., Loizou, G., Louisse, J., Lumen, A., Madden, J. C., Patterson, E. A., Proença, S., Punt, A., Setzer, R. W., Suciu, N., Troutman, J., Yoon, M., Worth, A., Tan, Y. M., Afd Pharmacoepi & Clinical Pharmacology, dIRAS RA-1, One Health Toxicologie, Dep IRAS

Publikováno v: Computational Toxicology
Computational Toxicology, 9, 61-72
Computational Toxicology, 9, 61. Elsevier BV
Computational Toxicology 9 (2019)

The fields of toxicology and chemical risk assessment seek to reduce, and eventually replace, the use of animals for the prediction of toxicity in humans. In this context, physiologically based kinetic (PBK) modelling based on in vitro and in silico

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194f1071d8713ee5cc0b2ef1b17494f3
https://doi.org/10.1016/j.comtox.2018.11.002