Silk nanoparticles for delivery of human BMP-2 in bone regenerative medicine applications

Autor: Bessa, Pc, Balmayor, Er, Cerqueira, Mt, Rada, T., Gomes, Me, Neves, Nm, Helena Azevedo, Casal, M., Reis, Rl

Publikováno v: CIÊNCIAVITAE
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[Excerpt] A tissue engineering approach combines the use of scaffold biomaterials, stem cells and growth factors. Bone morphogenetic proteins (BMPs) are growth factors that have sparked a great interest in tissue engineering due to their strong abili

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Silk fibroin microparticles as carriers for delivery of human recombinant bone morphogenetic protein-2: in vitro and in vivo bioactivity.

Autor: Bessa PC; 3B's Research Group-Biomaterials, Biodegradables, and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Guimarães, Portugal. paulo.bessa@dep.uminho.pt, Balmayor ER, Hartinger J, Zanoni G, Dopler D, Meinl A, Banerjee A, Casal M, Redl H, Reis RL, van Griensven M

Publikováno v: Tissue engineering. Part C, Methods [Tissue Eng Part C Methods] 2010 Oct; Vol. 16 (5), pp. 937-45.

Thermoresponsive self-assembled elastin-based nanoparticles for delivery of BMPs.

Autor: Bessa PC; 3B's Research Group, Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, 4806-909 Taipas, Guimarães, Portugal. paulo.bessa@dep.uminho.pt, Machado R, Nürnberger S, Dopler D, Banerjee A, Cunha AM, Rodríguez-Cabello JC, Redl H, van Griensven M, Reis RL, Casal M

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2010 Mar 19; Vol. 142 (3), pp. 312-8. Date of Electronic Publication: 2009 Nov 12.

Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery).

Autor: Bessa PC; 3Bs Research Group, Biomaterials, Biodegradables and Biomimetics, Department of Polymer Engineering, University of Minho, Campus de Gualtar, Braga, Portugal. paulo.bessa@dep.uminho.pt, Casal M, Reis RL

Publikováno v: Journal of tissue engineering and regenerative medicine [J Tissue Eng Regen Med] 2008 Mar-Apr; Vol. 2 (2-3), pp. 81-96.

Osteoinduction in human fat-derived stem cells by recombinant human bone morphogenetic protein-2 produced in Escherichia coli.

Autor: Bessa PC; 3B's Research Group - Biomaterials, Biodegradables and Biomimetics, Department of Polymer Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. paulo.bessa@dep.uminho.pt, Pedro AJ, Klösch B, Nobre A, van Griensven M, Reis RL, Casal M

Publikováno v: Biotechnology letters [Biotechnol Lett] 2008 Jan; Vol. 30 (1), pp. 15-21. Date of Electronic Publication: 2007 Aug 03.