Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Besarte Vrellaku"'
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The ability§ of the heart to adapt to changes in the mechanical environment is critical for normal cardiac physiology. The role of nitric oxide is increasingly recognized as a mediator of mechanical signaling. Produced in the heart by nitric oxide s
Externí odkaz:
https://doaj.org/article/1ee53f0cc039419e8c4b7fb705e0d039
Autor:
Manuela Zaccolo, Nadiia Rawlings, Philip Eaton, Parag R Gajendragadkar, Raja Jayaram, Pawel Swietach, Stefania Monterisi, Besarte Vrellaku, Gerard A Marchal, Sandy Chu, Keith M. Channon, Jillian N. Simon, Barbara Casadei, Dominic Waithe, Rana Sayeed, Oliver Lomas
Reperfusion-induced calcium overload profoundly affects the extent of myocardial injury following ischemia, impacting long-term morbidity and mortality. Reactive oxygen species play a crucial role in shaping the amplitude and spatiotemporal patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32326fe61e30a13d36bbb896168cae28
https://ora.ox.ac.uk/objects/uuid:5af84c5a-7a56-4fc4-9c82-c01f6c5cc840
https://ora.ox.ac.uk/objects/uuid:5af84c5a-7a56-4fc4-9c82-c01f6c5cc840
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
The ability§ of the heart to adapt to changes in the mechanical environment is critical for normal cardiac physiology. The role of nitric oxide is increasingly recognized as a mediator of mechanical signaling. Produced in the heart by nitric oxide s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e746af81f78109a85518bd76857f1d5
https://doi.org/10.3389/fphys.2020.606740
https://doi.org/10.3389/fphys.2020.606740
Autor:
Gerard A Marchal, Keith M. Channon, Oliver Lomas, Raja Jayaram, Besarte Vrellaku, Parag R Gajendragadkar, Nadiia Rawlings, Barbara Casadei, Pawel Swietach, Jillian N. Simon, Larissa Fabritz, Philip Eaton, Dominic Waithe, Sandy Chu, Rana Sayeed, Stefania Monterisi, Fahima Syeda, Manuela Zaccolo
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: Kinase oxidation is a critical signaling mechanism through which changes in the intracellular redox state alter cardiac function. In the myocardium, PKARIα (type-1 protein kinas
Background: Kinase oxidation is a critical signaling mechanism through which changes in the intracellular redox state alter cardiac function. In the myocardium, PKARIα (type-1 protein kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f7540b3bf718697aae0ed5bff330e19
https://doi.org/10.1161/circulationaha.120.046761
https://doi.org/10.1161/circulationaha.120.046761
Autor:
Dominic Waithe, Raja Jayaram, Sandy Chu, Jillian N. Simon, Stefania Monterisi, Phil Eaton, Besarte Vrellaku, Barbara Casadei, Rana Sayeed, Pawel Swietach, Nadiia Rawlings, Manuela Zaccolo, Oliver Lomas, Gerard A Marchal, Keith M. Channon, Parag R Gajendragadkar
Publikováno v:
Circulation. 142
Introduction: Kinase oxidation is a critical signaling mechanism through which changes in the intracellular redox state alter cardiac function. In the myocardium, the regulatory Iα subunit of Protein Kinase A (PKARIα) can be reversibly oxidised, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::083ed4616409fc32b2205ccd72ed5c98
https://doi.org/10.1161/circ.142.suppl_3.14219
https://doi.org/10.1161/circ.142.suppl_3.14219
Autor:
Gerard A Marchal, Keith M. Channon, Philip Eaton, Raja Jayaram, Pawel Swietach, Oliver Lomas, Parag R Gajendragadkar, Barbara Casadei, Dominic Waithe, Jillian N. Simon, Nadiia Rawlings, Sandy Chu, Besarte Vrellaku, Stefania Monterisi, Manuela Zaccolo
Publikováno v:
European Heart Journal. 40
Background Kinase oxidation is a critical signalling mechanism through which changes in the intracellular redox state alter cardiac function. In the myocardium, type-1 protein kinase A (PKARIα) can be reversibly oxidised, forming interprotein disulp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86e9b85cb1322d77e64eb29253597792
https://doi.org/10.1093/eurheartj/ehz748.0091
https://doi.org/10.1093/eurheartj/ehz748.0091