Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Bertrand Z, Yeung"'
Autor:
Sunny Z. Wu, Daniel L. Roden, Ghamdan Al-Eryani, Nenad Bartonicek, Kate Harvey, Aurélie S. Cazet, Chia-Ling Chan, Simon Junankar, Mun N. Hui, Ewan A. Millar, Julia Beretov, Lisa Horvath, Anthony M. Joshua, Phillip Stricker, James S. Wilmott, Camelia Quek, Georgina V. Long, Richard A. Scolyer, Bertrand Z. Yeung, Davendra Segara, Cindy Mak, Sanjay Warrier, Joseph E. Powell, Sandra O’Toole, Elgene Lim, Alexander Swarbrick
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background High throughput single-cell RNA sequencing (scRNA-Seq) has emerged as a powerful tool for exploring cellular heterogeneity among complex human cancers. scRNA-Seq studies using fresh human surgical tissue are logistically difficult
Externí odkaz:
https://doaj.org/article/a5ef0303cd954e8fa8a1cccb863078c6
Autor:
Marlon Stoeckius, Shiwei Zheng, Brian Houck-Loomis, Stephanie Hao, Bertrand Z. Yeung, William M. Mauck, Peter Smibert, Rahul Satija
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Despite rapid developments in single cell sequencing, sample-specific batch effects, detection of cell multiplets, and experimental costs remain outstanding challenges. Here, we introduce Cell Hashing, where oligo-tagged antibodies against u
Externí odkaz:
https://doaj.org/article/8f61de2b6f854615844e6e5b104c3bad
Autor:
Jin Wang, Bertrand Z. Yeung, M. Guillaume Wientjes, Minjian Cui, Cody J. Peer, Ze Lu, William D. Figg, Sukyung Woo, Jessie L.-S. Au
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 997 (2021)
Exosomes, naturally occurring vesicles secreted by cells, are undergoing development as drug carriers. We used experimental and computational studies to investigate the kinetics of intracellular exosome processing and exosome-mediated drug efflux and
Externí odkaz:
https://doaj.org/article/eafa1fff3c4641eaa643cb4240fc6d8c
Autor:
Mayu Hata, Tse Shun Huang, Leif S. Ludwig, Caleb A. Lareau, Wendy Luo, Aviv Regev, James B. Wing, Yusuke Takeshima, Shimon Sakaguchi, Efthymia Papalexi, Peter Smibert, Rahul Satija, Pratiksha I. Thakore, Yuhan Hao, Kristopher L. Nazor, Bertrand Z. Yeung, Kelvin Y. Chen, Vijay G. Sankaran, Andre Luiz Zorzetto-Fernandes, Tatsuya Kibayashi, Eleni P. Mimitou
Publikováno v:
Nature Biotechnology. 39:1246-1258
Recent technological advances have enabled massively parallel chromatin profiling with scATAC-seq (single-cell assay for transposase accessible chromatin by sequencing). Here we present ATAC with select antigen profiling by sequencing (ASAP-seq), a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd4ba0457c1490d3c5a98e889be2c43
https://doi.org/10.1038/s41587-021-00927-2
https://doi.org/10.1038/s41587-021-00927-2
Autor:
Rahul Satija, William M. Mauck, Bernadette Bracken, Andrew Butler, Efthymia Papalexi, Eleni P. Mimitou, Yuhan Hao, Hans-Hermann Wessels, Samantha D. Foster, Bertrand Z. Yeung, Peter Smibert
Publikováno v:
Nature genetics
The expression of inhibitory immune checkpoint molecules, such as programmed death-ligand (PD-L)1, is frequently observed in human cancers and can lead to the suppression of T cell-mediated immune responses. Here, we apply expanded CRISPR-compatible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302ec219a1bd39f2dc8c2191eb1ef9fb
https://doi.org/10.1038/s41588-021-00778-2
https://doi.org/10.1038/s41588-021-00778-2
Autor:
Ghamdan Al-Eryani, Nenad Bartonicek, Chia-Ling Chan, Alma Anderson, Kate Harvey, Sunny Z. Wu, Dan Roden, Taopeng Wang, John Reeves, Bertrand Z Yeung, Etienne Masle-Farquhar, Christopher C Goodnow, Cindy Ma, Tri G. Phan, Joakim Lundeberg, Simon Junankar, Alexander Swarbrick
SummaryImmune cells are critical determinants of solid tumour aetiology, but the diverse phenotypes of intra-tumoural immune cells remain incompletely characterised. We applied integrated single cell RNA sequencing (scRNA-Seq) and highly multiplexed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5027321c40e6f4306bcb9221555593d0
https://doi.org/10.1101/2022.05.31.494081
https://doi.org/10.1101/2022.05.31.494081
Autor:
Traci Legere, Pradeep B. J. Reddy, Korey A. Walter, Bali Pulendran, Prabhu S. Arunachalam, Shankar Subramaniam, Florian Wimmers, Madeleine K D Scott, Celia C. LaBranche, Bertrand Z. Yeung, John P. Vasilakos, Venkata S. Bollimpelli, Samantha L. Burton, Sailaja Gangadhara, Sudhir Pai Kasturi, Shakti Gupta, Cynthia A. Derdeyn, Caroline Petitdemange, Pamela A. Kozlowski, David C. Montefiori, Tiffany M. Styles, Thomas J. Ketas, John P. Moore, Chil Yong Kang, Rama Rao Amara, Eric Hunter, George M. Shaw, Purvesh Khatri, Mark A. Tomai, Anthony Tsai, David Masopust, Vineet Joag, Clare F. Quarnstrom, Tysheena P. Charles
Publikováno v:
Nature Medicine
Recent efforts toward an HIV vaccine focus on inducing broadly neutralizing antibodies, but eliciting both neutralizing antibodies (nAbs) and cellular responses may be superior. Here, we immunized macaques with an HIV envelope trimer, either alone to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ad3f6afa379c5c408d930aefb7aaee
https://doi.org/10.1038/s41591-020-0858-8
https://doi.org/10.1038/s41591-020-0858-8
Autor:
Bertrand Z. Yeung, Matthew H. Spitzer, Aidan F. Winters, Whitney Tamaki, Yun S. Song, Byungjin Hwang, Yang Sun, Anton Ogorodnikov, Chun Jimmie Ye, David Lee, Kristopher L. Nazor, Eric D. Chow, George C. Hartoularos
Publikováno v:
Nature methods, vol 18, iss 8
Nat Methods
Nat Methods
The development of DNA-barcoded antibodies to tag cell surface molecules has enabled the use of droplet-based single-cell sequencing (dsc-seq) to profile protein abundances from thousands of cells simultaneously. As compared to flow and mass cytometr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00be87dc685c92548a45dedb906c7f9
https://escholarship.org/uc/item/4h28g221
https://escholarship.org/uc/item/4h28g221
Autor:
William D. Figg, Bertrand Z. Yeung, M. Guillaume Wientjes, Minjian Cui, Jin Wang, Ze Lu, Jessie L.-S. Au, Sukyung Woo, Cody J. Peer
Publikováno v:
Pharmaceutics
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 997, p 997 (2021)
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 997, p 997 (2021)
Exosomes, naturally occurring vesicles secreted by cells, are undergoing development as drug carriers. We used experimental and computational studies to investigate the kinetics of intracellular exosome processing and exosome-mediated drug efflux and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039e433e927480cbbd00d81c9d503479
Autor:
Shiwei Zheng, Rahul Satija, Stephanie Hao, Bertrand Z. Yeung, Peter Smibert, Marlon Stoeckius, Brian Houck-Loomis, William M. Mauck
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-12 (2018)
Genome Biology
Genome Biology
Despite rapid developments in single cell sequencing, sample-specific batch effects, detection of cell multiplets, and experimental costs remain outstanding challenges. Here, we introduce Cell Hashing, where oligo-tagged antibodies against ubiquitous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e625617217c5f7286c2ec07eac1ff210
http://link.springer.com/article/10.1186/s13059-018-1603-1
http://link.springer.com/article/10.1186/s13059-018-1603-1