Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bertrand Montpellier"'
Autor:
Katrina Vanura, Bertrand Montpellier, Trang Le, Salvatore Spicuglia, Jean-Marc Navarro, Olivier Cabaud, Sandrine Roulland, Elodie Vachez, Immo Prinz, Pierre Ferrier, Rodrig Marculescu, Ulrich Jäger, Bertrand Nadel
Publikováno v:
PLoS Biology, Vol 5, Iss 3, p e43 (2007)
It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspect
Externí odkaz:
https://doaj.org/article/4d293e7183c54eb8b435bc0643a3316d
Autor:
Stephen Chang, Goce Bogdanoski, Amine Boudil, Irina Matei, Michael S. Krangel, Shaheena Bashir, Bertrand Montpellier, Julie S. Yuan, Han-Yu Shih, Veronique Voisin, Cynthia J. Guidos, Paul E. Kowalski, Gary D. Bader
Publikováno v:
Nature immunology
Signaling via the pre-T cell antigen receptor (pre-TCR) and the receptor Notch1 induces transient self-renewal (β-selection) of TCRβ(+) CD4(-)CD8(-) double-negative stage 3 (DN3) and DN4 progenitor cells that differentiate into CD4(+)CD8(+) double-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb1c51c9972f4fed96efeb24e465994
http://europepmc.org/articles/PMC4368453
http://europepmc.org/articles/PMC4368453
Autor:
Bertrand Montpellier, Christophe Picard, Jean Gabert, Marie Loosveld, Marie-Amélie Goujart, Lucie Hernandez, Lionel Chasson, Chantal Fossat, Jean-Marc Navarro, Stéphanie Gon, Bertrand Nadel, Mélanie Bonnet, Thomas Crouzet, Ester Morgado, Gérard Michel, Benoit Quilichini, Dominique Payet-Bornet
Publikováno v:
Genes, Chromosomes and Cancer. 53:52-66
MYC is a potent oncogene involved in ∼70% of human cancers, inducing tumorigenesis with high penetrance and short latency in experimental transgenic models. Accordingly, MYC is recognized as a major driver of T-cell acute lymphoblastic leukemia (T-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::294b6ec6afdd2c05b70dd24d3b3b401f
https://doi.org/10.1002/gcc.22117
https://doi.org/10.1002/gcc.22117
Autor:
Ashton Trotman-Grant, Juan Carlos Zúñiga-Pflücker, Cynthia J. Guidos, Tracy S. H. In, Michele K. Anderson, Kogulan Yoganathan, Amanda J. Moore, Bertrand Montpellier
Publikováno v:
Immunology and Cell Biology
Interleukin-7 receptor (IL-7R) signaling is critical for multiple stages of T-cell development, but a role in the establishment of the mature thymic architecture needed for T-cell development and thymocyte selection has not been established. Crosstal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6b76de231ebfb8b5b6d02de8ae2bb9
https://pubmed.ncbi.nlm.nih.gov/28890536
https://pubmed.ncbi.nlm.nih.gov/28890536
Autor:
Fraser McBlane, Bertrand Montpellier, Jean-Marc Navarro, Trang Le, Katrina Vanura, Bertrand Nadel, Rodrig Marculescu, Sandrine Roulland, Ulrich Jäger
Publikováno v:
DNA Repair
DNA Repair, 2006, 5 (9-10), pp.1246-58. ⟨10.1016/j.dnarep.2006.05.015⟩
DNA Repair, Elsevier, 2006, 5 (9-10), pp.1246-58. ⟨10.1016/j.dnarep.2006.05.015⟩
DNA Repair, 2006, 5 (9-10), pp.1246-58. ⟨10.1016/j.dnarep.2006.05.015⟩
DNA Repair, Elsevier, 2006, 5 (9-10), pp.1246-58. ⟨10.1016/j.dnarep.2006.05.015⟩
A large number of lymphoid malignancies is characterized by specific chromosomal translocations, which are closely linked to the initial steps of pathogenesis. The hallmark of these translocations is the ectopic activation of a silent proto-oncogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd7ac4b37b05df5edd6593e814ee935
https://doi.org/10.1016/j.dnarep.2006.05.015
https://doi.org/10.1016/j.dnarep.2006.05.015
Autor:
Claudine Schiff, Bertrand Montpellier, Julie Agopian, Bertrand Nadel, Michèle Milili, Sandrine Roulland, Pierre Grenot, Pascal Gauduchon, Jean Navarro, Pierre Lebailly
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, 2006, 203 (11), pp.2425-31. ⟨10.1084/jem.20061292⟩
Journal of Experimental Medicine, Rockefeller University Press, 2006, 203 (11), pp.2425-31. ⟨10.1084/jem.20061292⟩
Journal of Experimental Medicine
Journal of Experimental Medicine, 2006, 203 (11), pp.2425-31. ⟨10.1084/jem.20061292⟩
Journal of Experimental Medicine, Rockefeller University Press, 2006, 203 (11), pp.2425-31. ⟨10.1084/jem.20061292⟩
Follicular lymphoma (FL) is one of the most common B-cell lymphoma, and remains virtually incurable despite its relatively indolent nature. T(14;18)(q32;q21), the genetic hallmark and early initiating event of FL pathogenesis, is also present at low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271f5336f7db5bc723ce2a800c0e2979
http://europepmc.org/articles/PMC2118129
http://europepmc.org/articles/PMC2118129
Autor:
Rodney R. Miles, Lance Batchelor, Tatiana Perova, Radia M. Johnson, Elizabeth J. Manos, Bertrand Montpellier, Seth Welborn, Nikolaus S. Trede, Gerald J. Spangrude, David A. Jones, James E. Cox, William L. Heaton, Deepa Joshi, J. Kimble Frazer, Anna M. Eiring, Michael W. Deininger, Ali Sanati, Hossein Sofla, Archana M. Agarwal, Cynthia J. Guidos, Suzanne Ridges, Priya Choudhry, Markus Müschen, Henry Choi, Kaveri Balan, Matthew S. Sigman
To detect targeted antileukemia agents we have designed a novel, high-content in vivo screen using genetically engineered, T-cell reporting zebrafish. We exploited the developmental similarities between normal and malignant T lymphoblasts to screen a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a76656051d974a589e8e23aac0d403
https://resolver.caltech.edu/CaltechAUTHORS:20140416-132704999
https://resolver.caltech.edu/CaltechAUTHORS:20140416-132704999
Autor:
Emmanuelle Clappier, Olivier Delattre, Jean-Michel Cayuela, Bertrand Nadel, Alan M. Gewirtz, Alain Aurias, Hervé Dombret, Anna Kalota, Thierry Leblanc, André Baruchel, Willem A. Dik, Bertrand Montpellier, Jean Soulier, Pierre Walrafen, Wendy Cuccuini, Anton W. Langerak, François Sigaux, Antoine Crinquette
Publikováno v:
Blood, 110(4), 1251-1261. American Society of Hematology
Blood
Blood, 2007, Epub ahead of print. ⟨10.1182/blood-2006-12-064683⟩
Blood, American Society of Hematology, 2007, Epub ahead of print. ⟨10.1182/blood-2006-12-064683⟩
Blood
Blood, 2007, Epub ahead of print. ⟨10.1182/blood-2006-12-064683⟩
Blood, American Society of Hematology, 2007, Epub ahead of print. ⟨10.1182/blood-2006-12-064683⟩
The C-Myb transcription factor is essential for hematopoiesis, including in the T-cell lineage. The C-Myb locus is a common site of retroviral insertional mutagenesis, however no recurrent genomic involvement has been reported in human malignancies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c4f26855bf358cd283086492bc937f
https://pubmed.ncbi.nlm.nih.gov/17452517
https://pubmed.ncbi.nlm.nih.gov/17452517
Autor:
Bertrand Montpellier, Bertrand Nadel, Pierre Ferrier, Immo Prinz, Olivier Cabaud, Jean-Marc Navarro, Elodie Vachez, Katrina Vanura, Trang Le, Rodrig Marculescu, Sandrine Roulland, Ulrich Jäger, Salvatore Spicuglia
Publikováno v:
PLoS Biology
PLoS Biology, 2007, 5 (3), pp.e43. ⟨10.1371/journal.pbio.0050043⟩
PLoS Biology, Vol 5, Iss 3, p e43 (2007)
PLoS Biology, Public Library of Science, 2007, 5 (3), pp.e43. ⟨10.1371/journal.pbio.0050043⟩
PLoS Biology, 2007, 5 (3), pp.e43. ⟨10.1371/journal.pbio.0050043⟩
PLoS Biology, Vol 5, Iss 3, p e43 (2007)
PLoS Biology, Public Library of Science, 2007, 5 (3), pp.e43. ⟨10.1371/journal.pbio.0050043⟩
It has long been thought that signal joints, the byproducts of V(D)J recombination, are not involved in the dynamics of the rearrangement process. Evidence has now started to accumulate that this is not the case, and that signal joints play unsuspect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9709a9af42d56b3cafada6de55f55ccc
https://hal.science/hal-00165464
https://hal.science/hal-00165464
Autor:
Irina Matei, Bertrand Montpellier, Oliver Stueker, Stephen Chang, Queenie C. K. Cheung, Robin Haw, Peggy P.C. Wong, Vicki Ling, Gary D. Bader, Daniele Merico, Shaheena Bashir, Joseph Beyene, Jayne S. Danska, Cynthia J. Guidos
Publikováno v:
Blood. 120:3496-3496
Abstract 3496 Notch1 signaling is required at multiple stages of normal T-lymphocyte development. Notch1 is a transmembrane receptor that is physiologically activated when Notch ligands induce conformational changes that allow Notch1 cleavage by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72652f4ac6923879514bc189261977d4
https://doi.org/10.1182/blood.v120.21.3496.3496
https://doi.org/10.1182/blood.v120.21.3496.3496