Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Bertrand J Jean-Claude"'
Autor:
Suman Rao, Anne-Laure Larroque-Lombard, Lisa Peyrard, Cédric Thauvin, Zakaria Rachid, Christopher Williams, Bertrand J Jean-Claude
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117215 (2015)
Cancer cells are characterized by a complex network of interrelated and compensatory signaling driven by multiple kinases that reduce their sensitivity to targeted therapy. Therefore, strategies directed at inhibiting two or more kinases are required
Externí odkaz:
https://doaj.org/article/9e5c8bb4c3fe43b5b27a4d8dbfdc2d3a
Autor:
Casey G. Cohen, Yael Levy, Diana Toscano-Rivero, Ekaterina Manasherova, Nancy Agmon-Levin, Ron S. Kenett, Bertrand J. Jean-Claude, Bruce D. Mazer, Ran Hovav, Mona I. Kidon
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
IntroductionPeanut allergy (PA) in children is a major concern. There is a need for better biological material for both diagnosis and oral immunotherapy (OIT) treatments. The unique state of seeds at early reproductive stages may affect the allergeni
Externí odkaz:
https://doaj.org/article/c7bd1b1e2e2142e1a05276823ea318e5
Publikováno v:
Molecules, Vol 29, Iss 1, p 162 (2023)
Higher rates of peanut allergy have been observed in countries that commonly roast peanuts prior to consumption. Despite the importance of understanding the role of thermal processing in allergy and on peanut composition, studies toward generating si
Externí odkaz:
https://doaj.org/article/9e0d75f198984cd78e7ff269501577f8
Autor:
Caterina Facchin, Ana B. Fraga-Timiraos, Julie Schmitt, Nadia Babaa, Naveet Pannu, Antonio Aliaga, Anne-Laure Larroque, Bertrand J. Jean-Claude
Publikováno v:
Cells, Vol 12, Iss 6, p 914 (2023)
Background: ZR2002 is a dual EGFR-DNA-targeting combi-molecule that carries a chloroethyl group at the six-position of the quinazoline ring designed to alkylate DNA. Despite its good pharmacokinetics, ZR2002 is metabolized in vivo into dechlorinated
Externí odkaz:
https://doaj.org/article/bab38f54266047238e6fe55c77e6e168
Autor:
Bertrand J. Jean-Claude, You-Qiang Fang, Sabine Dauphin-Pierre, Anne-Laure Larroque, Margarita I. Todorova
Supplementary Figure 1 from Subcellular Distribution of a Fluorescence-Labeled Combi-Molecule Designed to Block Epidermal Growth Factor Receptor Tyrosine Kinase and Damage DNA with a Green Fluorescent Species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261eb06ad88f710d8f1447c4fa011de7
https://doi.org/10.1158/1535-7163.22484657.v1
https://doi.org/10.1158/1535-7163.22484657.v1
Autor:
Bertrand J. Jean-Claude, You-Qiang Fang, Sabine Dauphin-Pierre, Anne-Laure Larroque, Margarita I. Todorova
To monitor the subcellular distribution of mixed epidermal growth factor (EGF) receptor (EGFR)–DNA targeting drugs termed combi-molecules, we designed AL237, a fluorescent prototype, to degrade into a green fluorescent DNA damaging species and FD10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0053f2b7c4b6977053a12d055fd35d38
https://doi.org/10.1158/1535-7163.c.6531515
https://doi.org/10.1158/1535-7163.c.6531515
Autor:
Caterina Facchin, Ana Belen Fraga Timiraos, Brian Meehan, Nadia Babaa, Lata Adnani, Anne-Laure Larroque, Janusz Rak, Bertrand J Jean-Claude
Publikováno v:
Cancer Research. 83:1647-1647
Introduction. Glioblastoma multiforme (GBM) is the most aggressive form of primary brain tumours with an average survival rate of 12-18 months. The existing treatment (chemotherapy with temozolomide (TMZ)+radiotherapy) increases the median survival b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5c5fe22013c7ef276c5f21ee18fea24
https://doi.org/10.1158/1538-7445.am2023-1647
https://doi.org/10.1158/1538-7445.am2023-1647
Publikováno v:
Inorganic Chemistry Communications. 106:217-223
The preparation of new complexes containing 2-amino-4,6-mercaptotriazine (HAT) [Zn(AT)2(H2O)2], [Zn(bpy)(AT)Cl(H2O)], [Zn(PPh3)2(AT)Cl(H2O)] and cis-[Mo2O5(AT)2] is reported. The structures of these complexes are discussed using IR, NMR, UV–Vis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e2dfe4f8be5c00caad4dc3f054d0c1
https://doi.org/10.1016/j.inoche.2019.04.024
https://doi.org/10.1016/j.inoche.2019.04.024
Autor:
Bertrand J. Jean-Claude, Hatem M. Titi, Neveen A. Annan, Ian S. Butler, Yahia El-Lazeik, Sahar I. Mostafa
Publikováno v:
Inorganica Chimica Acta. 487:433-447
The syntheses of some new zinc(II), palladium(II), platinum(II), ruthenium(II), rhodium(III) and silver(I) complexes of kojic acid (Hka) in both the absence and the presence of N,N- (2,2′-bipyridyl) and P- (triphenylphosphine) ligands are reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76169fb6e0f982ef4969bb9da23b8b3a
https://doi.org/10.1016/j.ica.2018.12.031
https://doi.org/10.1016/j.ica.2018.12.031
Autor:
Suman Rao, Anne-Laure Larroque-Lombard, Cédric Thauvin, Lisa Peyrard, Bertrand J. Jean-Claude, Benoît Thibault, Martin Rupp
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9569, p 9569 (2021)
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9569, p 9569 (2021)
The median-effect principle proposed by Chou and Talalay is the most effective approach to parameterize interactions between several agents in combination. However, this method cannot be used to evaluate the effectiveness of equimolar drug combinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b9a72f70f285ab6f7ca2a738dc1f86
https://pubmed.ncbi.nlm.nih.gov/34502481
https://pubmed.ncbi.nlm.nih.gov/34502481