Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Bertrand Daignan‐Fornier"'
Autor:
Maëlle Duperray, Fanny Hardet, Elodie Henriet, Christelle Saint-Marc, Eric Boué-Grabot, Bertrand Daignan-Fornier, Karine Massé, Benoît Pinson
Publikováno v:
Cells, Vol 12, Iss 19, p 2379 (2023)
Purines are required for fundamental biological processes and alterations in their metabolism lead to severe genetic diseases associated with developmental defects whose etiology remains unclear. Here, we studied the developmental requirements for pu
Externí odkaz:
https://doaj.org/article/f76fcca561704dcd84739d4684061716
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Being able to reproduce and survive is fundamental to all forms of life. In primitive unicellular organisms, the emergence of quiescence as a reversible proliferation arrest has most likely improved cell survival under unfavorable environmental condi
Externí odkaz:
https://doaj.org/article/980346167115441783f7951ba5eec5ac
Autor:
Chloé Philippe, Benoît Pinson, Jim Dompierre, Véronique Pantesco, Benoît Viollet, Bertrand Daignan-Fornier, Michel Moenner
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 6, Pp 555-562 (2018)
AICAR (Acadesine) is a pharmacological precursor of purine nucleotide biosynthesis with anti-tumoral properties. Although recognized as an AMP mimetic activator of the protein kinase AMPK, the AICAR monophosphate derivative ZMP was also shown to medi
Externí odkaz:
https://doaj.org/article/f8b13ada0770436c8378f60106b2ad78
Publikováno v:
eLife, Vol 8 (2019)
Metabolism is a highly integrated process resulting in energy and biomass production. While individual metabolic routes are well characterized, the mechanisms ensuring crosstalk between pathways are poorly described, although they are crucial for hom
Externí odkaz:
https://doaj.org/article/e5cdb278106e458e886146dad1811a14
Publikováno v:
Cells, Vol 8, Iss 1, p 67 (2019)
Purine nucleotides are involved in a multitude of cellular processes, and the dysfunction of purine metabolism has drastic physiological and pathological consequences. Accordingly, several genetic disorders associated with defective purine metabolism
Externí odkaz:
https://doaj.org/article/529854af60c7490894345444efcb549e
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-12 (2013)
Abstract Cell size is a complex quantitative trait resulting from interactions between intricate genetic networks and environmental conditions. Here, taking advantage of previous studies that uncovered hundreds of genes affecting budding yeast cell s
Externí odkaz:
https://doaj.org/article/84ff35a65c024ead961319be39f62f27
Publikováno v:
Metabolites, Vol 2, Iss 2, Pp 292-302 (2012)
AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate) is a natural metabolic intermediate of purine biosynthesis that is present in all organisms. In yeast, AICAR plays important regulatory roles under physiological condition
Externí odkaz:
https://doaj.org/article/3653f323b2af4d9baf098623b37054e0
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2556 (2008)
Polarity establishment and maintenance are crucial for morphogenesis and development. In budding yeast, these two intricate processes involve the superposition of regulatory loops between polarity landmarks, RHO GTPases, actin-mediated vesicles trans
Externí odkaz:
https://doaj.org/article/a12359447d0c45f5bb1d7257387ef7d7
Autor:
Thomas Pradeu, Bertrand Daignan‐Fornier, Andrew Ewald, Pierre‐Luc Germain, Samir Okasha, Anya Plutynski, Sébastien Benzekry, Marta Bertolaso, Mina Bissell, Joel S. Brown, Benjamin Chin‐Yee, Ian Chin‐Yee, Hans Clevers, Laurent Cognet, Marie Darrason, Emmanuel Farge, Jean Feunteun, Jérôme Galon, Elodie Giroux, Sara Green, Fridolin Gross, Fanny Jaulin, Rob Knight, Ezio Laconi, Nicolas Larmonier, Carlo Maley, Alberto Mantovani, Violaine Moreau, Pierre Nassoy, Elena Rondeau, David Santamaria, Catherine M. Sawai, Andrei Seluanov, Gregory D. Sepich‐Poore, Vanja Sisirak, Eric Solary, Sarah Yvonnet, Lucie Laplane
Publikováno v:
Biological Reviews.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0722a56f58c156ce7b7020f01c8a84d2
https://doi.org/10.1111/brv.12971
https://doi.org/10.1111/brv.12971
Autor:
Bertrand Daignan-Fornier, Johanna Ceschin, Claire Almyre, Benoît Pinson, Christelle Saint-Marc
Publikováno v:
Current Genetics
Current Genetics, Springer Verlag, 2020, 66 (6), pp.1163-1177. ⟨10.1007/s00294-020-01101-y⟩
Current Genetics, Springer Verlag, 2020, 66 (6), pp.1163-1177. ⟨10.1007/s00294-020-01101-y⟩
International audience; Because metabolism is a complex balanced process involving multiple enzymes, understanding how organisms compensate for transient or permanent metabolic imbalance is a challenging task that can be more easily achieved in simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033a65b24f7e562c2e7ad0f2618a2875
https://hal.archives-ouvertes.fr/hal-02992968
https://hal.archives-ouvertes.fr/hal-02992968
