Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Bertrand Crozatier"'
Autor:
Marianne Mazevet, Anissa Belhadef, Maxance Ribeiro, Delphine Dayde, Anna Llach, Marion Laudette, Tiphaine Belleville, Philippe Mateo, Mélanie Gressette, Florence Lefebvre, Ju Chen, Christilla Bachelot-Loza, Catherine Rucker-Martin, Frank Lezoualch, Bertrand Crozatier, Jean-Pierre Benitah, Marie-Catherine Vozenin, Rodolphe Fischmeister, Ana-Maria Gomez, Christophe Lemaire, Eric Morel
Publikováno v:
eLife, Vol 12 (2023)
Anthracyclines, such as doxorubicin (Dox), are widely used chemotherapeutic agents for the treatment of solid tumors and hematologic malignancies. However, they frequently induce cardiotoxicity leading to dilated cardiomyopathy and heart failure. Thi
Externí odkaz:
https://doaj.org/article/cdffeb33bb6c47cd87e41bc7a93230d4
Autor:
Christophe Lemaire, Bertrand Crozatier, Frank Lezoualc'h, M Ribeiro, Marianne Mazevet, A.M. Gomez, A Belhadef, M. Laudette, Jean-Pierre Benitah, Eric Morel
Publikováno v:
European Heart Journal. 40
Introduction Doxorubicin (Dox) is an anthracycline commonly used to treat many types of cancer; unfortunately this chemotherapeutic agent induces many side effects such as cardiotoxicity leading to dilated cardiomyopathy (DCM). The cardiotoxicity of
Autor:
Frank Lezoualc'h, Christophe Lemaire, Marianne Mazevet, Bertrand Crozatier, Maisa de Souza Ribeiro, A. Belhadef, A.M. Gomez, Jean-Pierre Benitah, Eric Morel
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 12:243-244
Introduction Anticancer treatments (chemo- and radiation therapies), such as Doxorubicin (Dox), used to treat many types of cancer are associated with many side effects such as cardiotoxicity mainly leading to a dilated cardiomyopathy (DCM) in chroni
Autor:
Frank Lezoualc'h, A.M. Gomez, Bertrand Crozatier, Christophe Lemaire, Marianne Mazevet, M. Laudette, A. Belhadef, Eric Morel, Maisa de Souza Ribeiro, Jean-Pierre Benitah
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 13:216
Introduction Doxorubicin (Dox) is an Anthracycline commonly used to treat many types of cancer; unfortunately this chemotherapeutic agent often induces side effects such as cardiotoxicity leading to cardiomyocyte death and dilated cardiomyopathy (DCM
Autor:
Bertrand Crozatier, Mathieu Couade, Wei-Ning Lee, Mathieu Pernot, Emmanuel Messas, Mickael Tanter, Philippe Mateo, Alain Bel
Publikováno v:
JACC: Cardiovascular Imaging. 9:1023-1030
Objectives The aim of this study was to investigate the potential of shear wave imaging (SWI), a novel ultrasound-based technique, to noninvasively quantify passive diastolic myocardial stiffness in an ovine model of ischemic cardiomyopathy. Backgrou
Autor:
Maxance Ribeiro, Jean-Pierre Benitah, Audrey Ridoux, Rodolphe Fischmeister, Philippe Mateo, Ana Maria Gomez, Eric Morel, Marianne Mazevet, Anna Llach, Catherine Rucker-Martin, Olivier Villejouvert, Bertrand Crozatier
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, Elsevier, In press, ⟨10.1016/j.yjmcc.2018.11.019⟩
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Journal of Molecular and Cellular Cardiology, Elsevier, In press, ⟨10.1016/j.yjmcc.2018.11.019⟩
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
International audience; Cardiac failure is a common complication in cancer survivors treated with anthracyclines. Here we followed up cardiac function and excitation-contraction (EC) coupling in an in vivo doxorubicin (Dox) treated mice model (iv, to
Autor:
Eric Morel, Bertrand Crozatier, Anne-Coline Laurent, Isabelle Hmitou, Mélanie Métrich, Nicolas Duquesnes, Magali Breckler, Delphine Courillau, Jean-Paul Blondeau, Frank Lezoualc'h
Publikováno v:
Cellular Signalling. 22:1459-1468
Epac (Exchange protein directly activated by cAMP) is a sensor for cAMP and represents a novel mechanism for governing cAMP signalling. Epac is a guanine nucleotide exchange factor (GEF) for the Ras family of small GTPases, Rap. Previous studies demo
Autor:
Frank Lezoualc'h, Eric Morel, Ana María Gómez, Bertrand Crozatier, Magali Berthouze, Mélanie Métrich
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 459:535-546
Exchange proteins directly activated by cyclic AMP (Epac) were discovered 10 years ago as new sensors for the second messenger cyclic AMP (cAMP). Epac family, including Epac1 and Epac2, are guanine nucleotide exchange factors for the Ras-like small G
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 41:1173-1181
Myocardial stretch is a major determinant of ventricular hypertrophy, a physiological adaptational process that can be detrimental, leading to heart failure. Therapies aimed to limit the development of cardiac hypertrophy are thus currently evaluated
Autor:
Mathieu, Pernot, Wei-Ning, Lee, Alain, Bel, Philippe, Mateo, Mathieu, Couade, Mickaël, Tanter, Bertrand, Crozatier, Emmanuel, Messas
Publikováno v:
JACC. Cardiovascular imaging. 9(9)
The aim of this study was to investigate the potential of shear wave imaging (SWI), a novel ultrasound-based technique, to noninvasively quantify passive diastolic myocardial stiffness in an ovine model of ischemic cardiomyopathy.Evaluation of diasto