Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

Autor: Anas Allam, Laure Maigre, Julia Vergalli, Estelle Dumont, Bertrand Cinquin, Rodolphe Alves de Sousa, Jelena Pajovic, Elizabeth Pinet, Nikaia Smith, Jean-Philippe Herbeuval, Matthieu Réfrégiers, Isabelle Artaud, Jean-Marie Pagès

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibi

Externí odkaz: https://doaj.org/article/ca80691df79d435fac589a85f21b0920

Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells

Autor: Fernando Ugarte, Rebekah Sousae, Bertrand Cinquin, Eric W. Martin, Jana Krietsch, Gabriela Sanchez, Margaux Inman, Herman Tsang, Matthew Warr, Emmanuelle Passegué, Carolyn A. Larabell, E. Camilla Forsberg

Publikováno v: Stem Cell Reports, Vol 5, Iss 5, Pp 728-740 (2015)

Epigenetic regulation serves as the basis for stem cell differentiation into distinct cell types, but it is unclear how global epigenetic changes are regulated during this process. Here, we tested the hypothesis that global chromatin organization aff

Externí odkaz: https://doaj.org/article/bb95f6cead0a4c0faa419918bd8984f2

Birbeck granule-like 'organized smooth endoplasmic reticulum' resulting from the expression of a cytoplasmic YFP-tagged langerin.

Autor: Cédric Lenormand, Coralie Spiegelhalter, Bertrand Cinquin, Sabine Bardin, Huguette Bausinger, Catherine Angénieux, Anita Eckly, Fabienne Proamer, David Wall, Ben Lich, Sylvie Tourne, Daniel Hanau, Yannick Schwab, Jean Salamero, Henri de la Salle

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60813 (2013)

Langerin is required for the biogenesis of Birbeck granules (BGs), the characteristic organelles of Langerhans cells. We previously used a Langerin-YFP fusion protein having a C-terminal luminal YFP tag to dynamically decipher the molecular and cellu

Externí odkaz: https://doaj.org/article/0a595cfae4a24f29811a0ecae94d54dd

i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster

Autor: Bertrand Cinquin, Joyce Y. Kao, Mark L. Siegal

Publikováno v: Bioimage Data Analysis Workflows ‒ Advanced Components and Methods ISBN: 9783030763930

Many of the methods developed for the analysis of bioimages focus on microscopy images on the cellular level. However, bioimages can also be used by biologists to assess non-cellular level morphological phenotypes. Collecting non-cellular images and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6627862a1259355e82e8fceec4ab578
https://doi.org/10.1007/978-3-030-76394-7_7

Interplay between Cellular Uptake, Intracellular Localization and the Cell Death Mechanism in Triphenylamine-Mediated Photoinduced Cell Death

Autor: Houcine Bougherara, Florence Mahuteau-Betzer, Françoise Simon, Marie-Paule Teulade-Fichou, Delphine Naud-Martin, Albert Moussaron, Rahima Chennoufi, Guillaume Bordeau, Céline Frochot, Patrick Tauc, Eric Deprez, Ngoc-Duong Trinh, Bertrand Cinquin, Béatrice Rambaud

Publikováno v: Scientific Reports
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-63991-9⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-63991-9⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Triphenylamines (TPAs) were previously shown to trigger cell death under prolonged one- or two-photon illumination. Their initial subcellular localization, before prolonged illumination, is exclusively cytoplasmic and they translocate to the nucleus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53551e295a8f1102a6a2d8a48f3d9e
https://hal.science/hal-02614144/file/s41598-020-63991-9.pdf