A Multitubular Kidney-on-Chip to Decipher Pathophysiological Mechanisms in Renal Cystic Diseases

Autor: Sarah Myram, Bastien Venzac, Brice Lapin, Aude Battistella, Fanny Cayrac, Bertrand Cinquin, Charles Cavaniol, Giacomo Gropplero, Isabelle Bonnet, Sophie Demolombe, Stéphanie Descroix, Sylvie Coscoy

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a major renal pathology provoked by the deletion of PKD1 or PKD2 genes leading to local renal tubule dilation followed by the formation of numerous cysts, ending up with renal failure in adultho

Externí odkaz: https://doaj.org/article/228122e82c43454b8846384e590894c0

Rhodamine B Doped ZnO Monodisperse Microcapsules: Droplet-Based Synthesis, Dynamics and Self-Organization of ZnO Nanoparticles and Dye Molecules

Autor: Najla Ghifari, Bertrand Cinquin, Adil Chahboun, Abdel I. El Abed

Publikováno v: Nanomaterials, Vol 10, Iss 12, p 2351 (2020)

In the present work, droplet-based microfluidics and sol-gel techniques were combined to synthesize highly monodisperse zinc oxide (ZnO) microspheres, which can be doped easily and precisely with dyes, such as rhodamine B (RhB), and whose size can be

Externí odkaz: https://doaj.org/article/f88f3239fa98453d8833dd9f78b582d2

Homogenized Macroscale Model and Morphological Microscale Model to Understand the Varying Mechanical Properties of Scar Tissue of Hip Capsule Ligaments Grown Around Different Implant Materials

Autor: Samantha Sanders, Elisa Budyn, Angelina Avgeri, Laurent Sedel, Bertrand Cinquin, P. Bizot

Publikováno v: JOM. 73:2377-2389

In total hip arthroplasty, the hip joint is replaced by artificial materials. The fibrous tissue that re-forms around the hip joint after surgery plays an important role in joint stability. Here, the morphological and mechanical properties of the sca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::578a6983833513f2aea1e1ae2b7e4193
https://doi.org/10.1007/s11837-021-04737-4

i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster

Autor: Bertrand Cinquin, Joyce Y. Kao, Mark L. Siegal

Publikováno v: Bioimage Data Analysis Workflows ‒ Advanced Components and Methods ISBN: 9783030763930

Many of the methods developed for the analysis of bioimages focus on microscopy images on the cellular level. However, bioimages can also be used by biologists to assess non-cellular level morphological phenotypes. Collecting non-cellular images and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6627862a1259355e82e8fceec4ab578
https://doi.org/10.1007/978-3-030-76394-7_7

Interplay between Cellular Uptake, Intracellular Localization and the Cell Death Mechanism in Triphenylamine-Mediated Photoinduced Cell Death

Autor: Houcine Bougherara, Florence Mahuteau-Betzer, Françoise Simon, Marie-Paule Teulade-Fichou, Delphine Naud-Martin, Albert Moussaron, Rahima Chennoufi, Guillaume Bordeau, Céline Frochot, Patrick Tauc, Eric Deprez, Ngoc-Duong Trinh, Bertrand Cinquin, Béatrice Rambaud

Publikováno v: Scientific Reports
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-63991-9⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-63991-9⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

Triphenylamines (TPAs) were previously shown to trigger cell death under prolonged one- or two-photon illumination. Their initial subcellular localization, before prolonged illumination, is exclusively cytoplasmic and they translocate to the nucleus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53551e295a8f1102a6a2d8a48f3d9e
https://hal.science/hal-02614144/file/s41598-020-63991-9.pdf