Zobrazeno 1 - 10 of 73 pro vyhledávání: '"Bertrand, Castaing"'
1
Akademický článek
Structure-dependent recruitment and diffusion of guest proteins in liquid droplets of FUS
Autor: Kiyoto Kamagata, Nanako Iwaki, Saori Kanbayashi, Trishit Banerjee, Rika Chiba, Virginie Gaudon, Bertrand Castaing, Seiji Sakomoto
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Liquid droplets of a host protein, formed by liquid–liquid phase separation, recruit guest proteins and provide functional fields. Recruitment into p53 droplets is similar between disordered and folded guest proteins, whereas the diffusion
Externí odkaz: https://doaj.org/article/9435b28d0f5b47c88c8acdb84b2f6b18
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2
Akademický článek
OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression
Autor: Xhaferr Tanushi, Guillaume Pinna, Marie Vandamme, Capucine Siberchicot, Ostiane D’Augustin, Anne-Marie Di Guilmi, J. Pablo Radicella, Bertrand Castaing, Rebecca Smith, Sebastien Huet, François Leteurtre, Anna Campalans
Publikováno v: Frontiers in Cell and Developmental Biology, Vol 11 (2023)
One of the most abundant DNA lesions induced by Reactive oxygen species (ROS) is 8-oxoG, a highly mutagenic lesion that compromises genetic instability when not efficiently repaired. 8-oxoG is specifically recognized by the DNA-glycosylase OGG1 that
Externí odkaz: https://doaj.org/article/fb33b2e5d9f54efa87ae4201e6d9c02a
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3
Akademický článek
Molecular principles of recruitment and dynamics of guest proteins in liquid droplets
Autor: Kiyoto Kamagata, Nanako Iwaki, Milan Kumar Hazra, Saori Kanbayashi, Trishit Banerjee, Rika Chiba, Seiji Sakomoto, Virginie Gaudon, Bertrand Castaing, Hiroto Takahashi, Michiko Kimura, Hiroyuki Oikawa, Satoshi Takahashi, Yaakov Levy
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Despite the continuous discovery of host and guest proteins in membraneless organelles, complex host–guest interactions hinder the understanding of the molecular grammar governing liquid–liquid phase separation. In this study, we charact
Externí odkaz: https://doaj.org/article/8076c09dbce8459386b631ea88ef4285
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4
Akademický článek
Three‐dimensional structures of avian beta‐microseminoproteins: insight from the chicken egg‐specific beta‐microseminoprotein 3 paralog
Autor: Franck Coste, Thierry Moreau, Valérie Labas, Magali Chessé, Mégane Bregeon, Hervé Meudal, Karine Loth, Bertrand Castaing, Nicolas Guyot, Sophie Réhault‐Godbert
Publikováno v: FEBS Open Bio, Vol 11, Iss 6, Pp 1739-1756 (2021)
Beta‐microseminoproteins (MSMBs) are small disulfide‐rich proteins that are conserved among vertebrates. These proteins exhibit diverse biological activities and were mainly reported to play a role in male fertility, immunity, and embryogenesis.
Externí odkaz: https://doaj.org/article/0a0f15331a8142c5909d5978e5540926
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5
Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells
Autor: Ostiane D’Augustin, Virginie Gaudon, Capucine Siberchicot, Rebecca Smith, Catherine Chapuis, Jordane Depagne, Xavier Veaute, Didier Busso, Anne-Marie Di Guilmi, Bertrand Castaing, J Pablo Radicella, Anna Campalans, Sébastien Huet
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2023, pp.gkad243. ⟨10.1093/nar/gkad243⟩
The DNA-glycosylase OGG1 oversees the detection and clearance of the 7,8-dihydro-8-oxoguanine (8-oxoG), which is the most frequent form of oxidized base in the genome. This lesion is deeply buried within the double-helix and its detection requires ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bf0b6e30b09be31624bfb9165408b5
https://doi.org/10.1093/nar/gkad243
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6
Akademický článek
Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1
Autor: Alan Wacquiez, Franck Coste, Emmanuel Kut, Virginie Gaudon, Sascha Trapp, Bertrand Castaing, Daniel Marc
Publikováno v: Viruses, Vol 12, Iss 9, p 947 (2020)
The non-structural protein NS1 of influenza A viruses is an RNA-binding protein of which its activities in the infected cell contribute to the success of the viral cycle, notably through interferon antagonism. We have previously shown that NS1 strong
Externí odkaz: https://doaj.org/article/3e53aa9508f14674a37d255a8f698c86
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8
Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing
Autor: Franck, Coste, Goffinont, Stéphane, Cros, Julien, Gaudon, Virginie, Martine, Guérin, Garnier, Norbert, Fabrice, Confalonieri, Flament, Didier, Suskiewicz, Marcin Jozef, Bertrand, Castaing
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac932⟩
International audience; Abstract 8-Oxoguanine (GO) is a major purine oxidation product in DNA. Because of its highly mutagenic properties, GO absolutely must be eliminated from DNA. To do this, aerobic and anaerobic organisms from the three kingdoms
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3515::8751cfc874e10ffe5bcc6cd6c1f5b462
https://hal.science/hal-03841526/file/2022_NAR_castaing.pdf
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9
Three‐dimensional structures of avian beta‐microseminoproteins: insight from the chicken egg‐specific beta‐microseminoprotein 3 paralog
Autor: Bertrand Castaing, Mégane Bregeon, Valérie Labas, Magali Chessé, Karine Loth, Nicolas Guyot, Hervé Meudal, Thierry Moreau, Sophie Réhault-Godbert, Franck Coste
Publikováno v: FEBS Open Bio, Vol 11, Iss 6, Pp 1739-1756 (2021)
FEBS Open Bio
FEBS Open Bio, Wiley Open Access/Elsevier, In press, 11 (6), pp.1739-1756. ⟨10.1002/2211-5463.13166⟩
'FEBS Open Bio ', vol: 11, pages: 1739-1756 (2021)
FEBS Open Bio, 2021, 11 (6), pp.1739-1756. ⟨10.1002/2211-5463.13166⟩
Beta‐microseminoproteins (MSMBs) are small disulfide‐rich proteins that are conserved among vertebrates. These proteins exhibit diverse biological activities and were mainly reported to play a role in male fertility, immunity, and embryogenesis.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4701e49cf3e05718a541c8eabe134dda
https://doaj.org/article/0a0f15331a8142c5909d5978e5540926
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10
Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic
Autor: Stéphane Goffinont, Franck Coste, Pierre Prieu-Serandon, Lucija Mance, Virginie Gaudon, Norbert Garnier, Bertrand Castaing, Marcin Józef Suskiewicz
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, In press, ⟨10.1016/j.jbc.2023.104870⟩
International audience; Protein SUMOylation is a ubiquitylation-like post-translational modification (PTM) that is synthesised through an enzymatic cascade involving an E1 (SAE1:SAE2), an E2 (UBC9), and various E3 enzymes. In the final step of this p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6356ecc12a3391008fd61fd536b05ba2
https://doi.org/10.1016/j.jbc.2023.104870
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