Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bertram, Jacobs"'
Autor:
Liqiang Zhang, Yize Henry Li, Karen Kibler, Simona Kraberger, Arvind Varsani, Julie Turk, Nora Elmadbouly, Emily Aliskevich, Laurel Spaccarelli, Bereket Estifanos, Junior Enow, Isabela Rivabem Zanetti, Nicholas Saldevar, Efrem Lim, Jessika Schlievert, Kyle Browder, Anjali Wilson, Fernando Arcos Juan, Aubrey Pinteric, Aman Garg, Henna Monder, Rohan Saju, Savanah Gisriel, Bertram Jacobs, Timothy L Karr, Esther Borges Florsheim, Vivek Kumar, John Wallen, Masmudur Rahman, Grant McFadden, Brenda G Hogue, Alexandra R Lucas
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp 1-19 (2023)
Abstract SARS‐CoV‐2 acute respiratory distress syndrome (ARDS) induces uncontrolled lung inflammation and coagulopathy with high mortality. Anti‐viral drugs and monoclonal antibodies reduce early COVID‐19 severity, but treatments for late‐s
Externí odkaz:
https://doaj.org/article/173774a4d3874632894de3a50c2ec7e5
Autor:
Chelsae R. Watters, Oumar Barro, Natalie M. Elliott, Yumei Zhou, Musa Gabere, Elizabeth Raupach, Alexander T. Baker, Michael T. Barrett, Kenneth H. Buetow, Bertram Jacobs, Mahesh Seetharam, Mitesh J. Borad, Bolni Marius Nagalo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 4-14 (2023)
Vesiculoviruses are attractive oncolytic virus platforms due to their rapid replication, appreciable transgene capacity, broad tropism, limited preexisting immunity, and tumor selectivity through type I interferon response defects in malignant cells.
Externí odkaz:
https://doaj.org/article/0f9b4133faac47bdbaa01ba69e5b9a37
Autor:
Bolni Marius Nagalo, Yumei Zhou, Emilien J. Loeuillard, Chelsae Dumbauld, Oumar Barro, Natalie M. Elliott, Alexander T. Baker, Mansi Arora, James M. Bogenberger, Nathalie Meurice, Joachim Petit, Pedro Luiz Serrano Uson, Faaiq Aslam, Elizabeth Raupach, Musa Gabere, Alexei Basnakian, Camila C. Simoes, Martin J. Cannon, Steven R. Post, Kenneth Buetow, Jean Christopher Chamcheu, Michael T. Barrett, Dan G. Duda, Bertram Jacobs, Richard Vile, Michael A. Barry, Lewis R. Roberts, Sumera Ilyas, Mitesh J. Borad
Publikováno v:
Hepatology. 77:1943-1957
Morreton virus (MORV) is an oncolytic Vesiculovirus, genetically distinct from vesicular stomatitis virus (VSV).To report that MORV induced potent cytopathic effects (CPEs) in cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC) in vitro model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f63cf826059e949d0d3232e2f3cae4
https://doi.org/10.1002/hep.32769
https://doi.org/10.1002/hep.32769
Autor:
Masmudur M. Rahman, Bereket Estifanos, Honor L. Glenn, Karen Kibler, Yize Li, Bertram Jacobs, Grant McFadden, Brenda G. Hogue
Publikováno v:
bioRxiv
Nucleocytoplasmic transport of proteins using XPO1 (exportin 1) plays a vital role in cell proliferation and survival. Many viruses also exploit this pathway to promote infection and replication. Thus, inhibiting XPO1-mediated nuclear export with sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd40cb2e8b3072a95b862ef87748eb5d
https://europepmc.org/articles/PMC9948980/
https://europepmc.org/articles/PMC9948980/
Autor:
Liqiang Zhang, Yize (Henry) Li, Karen Kibler, Simona Kraberger, Arvind Varsani, Julie Turk, Nora Elmadbouly, Emily Aliskevich, Laurel Spaccarelli, Bereket Estifanos, Junior Enow, Isabela Rivabem Zanetti, Nicholas Saldevar, Efrem Lim, Kyle Browder, Anjali Wilson, Fernando Arcos Juan, Aubrey Pinteric, Aman Garg, Savanah Gisriel, Bertram Jacobs, Timothy L. Karr, Esther Borges Florsheim, Vivek Kumar, John Wallen, Masmudur Rahman, Grant McFadden, Brenda G. Hogue, Alexandra R. Lucas
1.AbstractSevere acute respiratory distress syndrome (ARDS) during SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) infection, manifests as uncontrolled lung inflammation and systemic thrombosis with high mortality. Anti-viral drugs and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e56688a6aca270e1b1cde3d8bc2d850
https://doi.org/10.1101/2022.09.09.507363
https://doi.org/10.1101/2022.09.09.507363
Autor:
Bolni Marius Nagalo, Yumei Zhou, Emilien J. Loeuillard, Chelsae Dumbauld, Oumar Barro, Natalie M. Elliott, Alexander T. Baker, Mansi Arora, James M. Bogenberger, Nathalie Meurice, Joachim Petit, Pedro Luiz Serrano Uson Junior, Faaiq Aslam, Jean Christopher Chamcheu, Camila C. Simoes, Martin J. Cannon, Alexei Basnakian, Steven R. Post, Kenneth Buetow, Michael T. Barrett, Dan G. Duda, Bertram Jacobs, Richard Vile, Michael A. Barry, Lewis R. Roberts, Sumera Ilyas, Mitesh J. Borad
Morreton virus (MORV) is a novel oncolyticVesiculovirus, genetically distinct from vesicular stomatitis virus (VSV). we report that MORV induced potent cytopathic effects in a panel of cholangiocarcinoma (CCA) and hepatocellular carcinoma (HCC) cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::953e9d9541a8958883bda4c898b03feb
https://doi.org/10.1101/2022.03.10.483848
https://doi.org/10.1101/2022.03.10.483848
Autor:
Pedro Luiz Serrano, Uson Junior, Thomas T, DeLeon, James M, Bogenberger, Rish K, Pai, Heidi E, Kosiorek, Jun, Yin, Daniel H, Ahn, Mohammad Bassam, Sonbol, Tanios, Bekaii-Saab, Aaron S, Mansfield, Kenneth, Buetow, Gregory J, Gores, Rory, Smoot, George, Vasmatzis, Benjamin R, Kipp, Amit, Mahipal, Alexander T, Baker, Hani, Babiker, Oumar, Barro, Chelsae, Dumbauld, Yumei, Zhou, Faaiq N, Aslam, Michael, Barrett, Bertram, Jacobs, Nathalie, Meurice, Mansi, Arora, Joachim, Petit, Natalie, Elliott, Bolni, Nagalo, Marcela A, Salomao, Mitesh J, Borad
Publikováno v:
Digestive diseases and sciences. 67(8)
FGFR2 genomic alterations are observed in 10-20% of cholangiocarcinoma (CCA). Although FGFR2 fusions are an important actionable target, FGFR2 protein expression has not been thoroughly characterized.To evaluate FGFR2 protein expression in cholangioc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5cdaf11afb4139ec4edd0800e754cc26
https://pubmed.ncbi.nlm.nih.gov/34773565
https://pubmed.ncbi.nlm.nih.gov/34773565
Publikováno v:
Herbal Medicine: Open Access. 2
Herpes simplex virus 1, HSV1, is the primary cause of herpes labialis in humans. Drugs like acyclovir and its derivatives are available for treatment, but with increased use and the number of immune compromised patients, the development of resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff05b57b1cabca46e534b08eabef286f
https://doi.org/10.21767/2472-0151.100014
https://doi.org/10.21767/2472-0151.100014
Publikováno v:
Plant Physiology. 108:1259-1267
Plant virus or viroid infection stimulates the phosphorylation of a plant-encoded protein of M(r) 68,000 to 70,000 (now termed pPKR) that is associated with double-stranded RNA-stimulated protein kinase activity. Using various biochemical and immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04110d3e5fdaf203bf7566b07e96556e
https://doi.org/10.1104/pp.108.3.1259
https://doi.org/10.1104/pp.108.3.1259
Publikováno v:
Biochemistry. 38(19)
NFAT transcription factors play a central role in initiating T-cell activation through the induction of immediate-early T-cell specific genes including interleukin-2 (IL-2). NFAT transcription factors bind to a sequence in the IL-2 enhancer known as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eae109029d229809fcd5e5d5e8462c9
https://pubmed.ncbi.nlm.nih.gov/10320367
https://pubmed.ncbi.nlm.nih.gov/10320367