Effect of High-Titer Convalescent Plasma on Progression to Severe Respiratory Failure or Death in Hospitalized Patients with COVID-19 Pneumonia: A Randomized Clinical Trial

Autor: Menichetti, F., Popoli, P., Puopolo, M., Alegiani, S. S., Tiseo, G., Bartoloni, A., De Socio, G., Luchi, S., Blanc, P., Puoti, M., Toschi, E., Massari, M., Palmisano, L., Marano, G., Chiamenti, M., Martinelli, L., Franchi, S., Pallotto, C., Suardi, L. R., Pasqua, B. L., Merli, M., Fabiani, P., Bertolucci, L., Borchi, B., Modica, S., Moneta, S., Marchetti, G., d'Arminio Monforte, A., Stoppini, L., Ferracchiato, N., Piconi, S., Fabbri, C., Beccastrini, E., Saccardi, R., Giacometti, A., Esperti, S., Pierotti, P., Bernini, L., Bianco, C., Benedetti, S., Lanzi, A., Bonfanti, P., Sani, S., Saracino, A., Castagna, A., Trabace, L., Lanza, M., Focosi, D., Mazzoni, A., Pistello, M., Falcone, M., Locatelli, F., Ippolito, G., Magrini, N., Bernardini, R., Brusaferro, S., De Angelis, V., Perotti, C., Remuzzi, G., De Silvestro, G., Costantini, M., Bocchino, M., De Donno, G., Francisci, D.

Importance: Convalescent plasma (CP) has been generally unsuccessful in preventing worsening of respiratory failure or death in hospitalized patients with COVID-19 pneumonia. Objective: To evaluate the efficacy of CP plus standard therapy (ST) vs ST

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Effect of High-Titer Convalescent Plasma on Progression to Severe Respiratory Failure or Death in Hospitalized Patients With COVID-19 Pneumonia: A Randomized Clinical Trial.

Autor: Menichetti F; Infectious Disease Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Pisa, Italy., Popoli P; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy., Puopolo M; Department of Neuroscience, Istituto Superiore di Sanità, Rome, Italy., Spila Alegiani S; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy., Tiseo G; Infectious Disease Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Pisa, Italy., Bartoloni A; Infectious and Tropical Diseases Unit, Florence Department of Medicine, Careggi University Hospital, Florence, Italy., De Socio GV; Clinic of Infectious Diseases, 'Santa Maria della Misericordia' Hospital, University of Perugia, Perugia, Italy., Luchi S; Infectious Disease Unit, Hospital of Lucca, Lucca, Italy., Blanc P; Infectious Diseases, Ospedale S. Maria Annunziata, Firenze, Italy., Puoti M; University of Milano-Bicocca School of Medicine, Milan, Italy.; Azienda socio sanitaria territorial (ASST) Grande Ospedale Metropolitano Niguarda, Milan, Italy., Toschi E; Research Coordination and Support Service (CoRi), Istituto Superiore di Sanità, Rome, Italy., Massari M; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy., Palmisano L; National Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy., Marano G; Italian National Blood Centre, Rome, Italy., Chiamenti M; Unit of Infectious Diseases, Carlo Poma Hospital, Mantova, Italy., Martinelli L; Internal Medicine, Unità Sanitaria Locale (USL)-Umbria 1, Ospedale Città di Castello, Città di Castello, Italy., Franchi S; Internal Medicine, Unità Sanitaria Locale (USL)-Umbria 1, Ospedale Città di Castello, Città di Castello, Italy., Pallotto C; Infectious Diseases Unit, San Giuseppe Hospital, Azienda USL Toscana Centro, Empoli, Italy., Suardi LR; Infectious Disease Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Pisa, Italy.; Infectious Diseases Unit, San Giuseppe Hospital, Azienda USL Toscana Centro, Empoli, Italy., Luciani Pasqua B; Centro Regionale Sangue, Servizio Immunotrasfusionale, Azienda Ospedaliera di Perugia, Perugia, Italy., Merli M; Azienda socio sanitaria territorial (ASST) Grande Ospedale Metropolitano Niguarda, Milan, Italy., Fabiani P; Internal Medicine, Ospedale Unico della Versilia, Lido di Camaiore, Italy., Bertolucci L; Internal Medicine, Ospedale Unico della Versilia, Lido di Camaiore, Italy., Borchi B; Infectious and Tropical Diseases Unit, Florence Department of Medicine, Careggi University Hospital, Florence, Italy., Modica S; Infectious and Tropical Diseases Unit, Florence Department of Medicine, Careggi University Hospital, Florence, Italy., Moneta S; Infectious Disease Unit, Hospital of Lucca, Lucca, Italy., Marchetti G; Infectious Diseases Unit, Department of Health Sciences, ASST Santi Paolo e Carlo University Hospital, Milan, Italy., d'Arminio Monforte A; Infectious Diseases Unit, Department of Health Sciences, ASST Santi Paolo e Carlo University Hospital, Milan, Italy., Stoppini L; Internal Medicine, Ospedale di Foligno, Foligno, Italy., Ferracchiato N; Internal Medicine, Ospedale di Foligno, Foligno, Italy., Piconi S; Infectious Diseases, Azienda Ospedaliera di Lecco, Lecco, Italy., Fabbri C; Infectious Diseases, Ospedale San Jacopo, Pistoia, Italy., Beccastrini E; Cell Therapy and Transfusion Medicine, Careggi University Hospital, Florence, Italy., Saccardi R; Cell Therapy and Transfusion Medicine, Careggi University Hospital, Florence, Italy., Giacometti A; Azienda Ospedaliera Universitaria, Ospedali Riuniti di Ancona, Ancona, Italy., Esperti S; Infectious Diseases, Ospedale S. Maria Annunziata, Firenze, Italy., Pierotti P; Infectious Diseases, Ospedale S. Maria Annunziata, Firenze, Italy., Bernini L; Division of Infectious Diseases, Arezzo Hospital, Arezzo, Italy., Bianco C; Division of Infectious Diseases, Arezzo Hospital, Arezzo, Italy., Benedetti S; Clinic of Infectious Diseases, 'Santa Maria della Misericordia' Hospital, University of Perugia, Perugia, Italy., Lanzi A; Clinic of Infectious Diseases, 'Santa Maria della Misericordia' Hospital, University of Perugia, Perugia, Italy., Bonfanti P; Department of Infectious Diseases, ASST Monza, University of Milano-Bicocca, Milan, Italy., Massari M; Infectious Disease Unit, Azienda USL-Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) di Reggio Emilia, Reggio Emilia, Italy., Sani S; Infectious Diseases, Livorno Hospital, Livorno, Italy., Saracino A; Division of Infectious Diseases, Bari University Hospital, Bari, Italy., Castagna A; Infectious Diseases, IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy., Trabace L; Department of Experimental and Clinical Medicine, University of Foggia, Foggia, Italy., Lanza M; North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy., Focosi D; North-Western Tuscany Blood Bank, Pisa University Hospital, Pisa, Italy., Mazzoni A; Division of Transfusion Medicine and Transplant Biology, Pisa University Hospital, Pisa, Italy., Pistello M; Division of Virology, University Hospital of Pisa, Retrovirus Center, Department of Translational Research, University of Pisa, Pisa, Italy., Falcone M; Infectious Disease Unit, Department of Clinical and Experimental Medicine, Azienda Ospedaliera Universitaria Pisana, University of Pisa, Pisa, Italy.

Publikováno v: JAMA network open [JAMA Netw Open] 2021 Nov 01; Vol. 4 (11), pp. e2136246. Date of Electronic Publication: 2021 Nov 01.

Clinical comparative study of microcurrent electrical stimulation to mid-laser and placebo treatment in degenerative joint disease of the temporomandibular joint.

Autor: Bertolucci LE; Bertolucci Physical Therapy, Citrus Heights, California 95621, USA., Grey T

Publikováno v: Cranio : the journal of craniomandibular practice [Cranio] 1995 Apr; Vol. 13 (2), pp. 116-20.

Suppression of pregnancy-induced nausea and vomiting with sensory afferent stimulation.

Autor: Evans AT; Department of Obstetrics and Gynecology, University of California, Davis., Samuels SN, Marshall C, Bertolucci LE

Publikováno v: The Journal of reproductive medicine [J Reprod Med] 1993 Aug; Vol. 38 (8), pp. 603-6.