Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Bertolt Kreft"'
Autor:
Rienk Offringa, Ralf Lesche, Iris Oezen, Michael Platten, Daniel Baumann, Christiane A Opitz, Ahmed Sadik, Catherine Olesch, Frederik Cichon, Norbert Schmees, Ulrike Roehn, Florian Prinz, Detlef Stoeckigt, Katharina Sahm, Nirmeen Elmadany, Christina Kober, Julian Roewe, Lars Roese, Benjamin Bader, Mátyás Gorjánácz, Helge Gottfried Roider, Gabriele Leder, Horst Irlbacher, Julien Lefranc, Mine Oezcan-Wahlbrink, Ankita Sati Batra, Rafael Carretero, Hilmar Weinmann, Ingo V Hartung, Bertolt Kreft, Ilona Gutcher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background The metabolism of tryptophan to kynurenines (KYN) by indoleamine-2,3-dioxygenase or tryptophan-2,3-dioxygenase is a key pathway of constitutive and adaptive tumor immune resistance. The immunosuppressive effects of KYN in the tumor microen
Externí odkaz:
https://doaj.org/article/bc1e59d7b2b148a6869f255df5b9d454
Autor:
Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge, Eva Maria Gutierrez, Rafael Carretero, Christoph Freiberg, Uwe Gritzan, Merlin Luetke-Eversloh, Sven Golfier, Oliver Von Ahsen, Valentina Volpin, Antonio Sorrentino, Anchana Rathinasamy, Maria Xydia, Robert Lohmayer, Julian Sax, Ayse Nur-Menevse, Abir Hussein, Slava Stamova, Georg Beckmann, Julian Marius Glueck, Dorian Schoenfeld, Joerg Weiske, Dieter Zopf, Rienk Offringa, Bertolt Kreft, Philipp Beckhove, Joerg Willuda
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), a cell surface receptor, is expressed on normal epithelial tissue and highly expressed in cancers of high unmet medical need, such as non-small cell lung, pancreatic, and colorectal
Externí odkaz:
https://doaj.org/article/b51b522082204e19b3b78844000d71d5
Autor:
Lars Roese, Bertolt Kreft, Ilan Vaknin, Gady Cojocaru, Inbal Barbiro, Meir Azulay, Ofer Levy, Zurit Levine, Andrew Drake, Andrew Pow, John Hunter, Anna-Lena Frisk, Helge G. Roider, Sven Golfier, Merlin V. Luetke-Eversloh, Wolf-Dietrich Doecke, Ilona Gutcher, Uwe Gritzan, Julia Huetter
The immunoglobulin-like domain containing receptor 2 (ILDR2), a type I transmembrane protein belonging to the B7 family of immunomodulatory receptors, has been described to induce an immunosuppressive effect on T-cell responses. Besides its expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2144ef0b970d839bedb826181349a4
https://doi.org/10.1158/2326-6066.c.6550420
https://doi.org/10.1158/2326-6066.c.6550420
Autor:
Lars Roese, Bertolt Kreft, Ilan Vaknin, Gady Cojocaru, Inbal Barbiro, Meir Azulay, Ofer Levy, Zurit Levine, Andrew Drake, Andrew Pow, John Hunter, Anna-Lena Frisk, Helge G. Roider, Sven Golfier, Merlin V. Luetke-Eversloh, Wolf-Dietrich Doecke, Ilona Gutcher, Uwe Gritzan, Julia Huetter
Histopathological findings in 8 weeks and 12 months old wild-type and ILDR2-deficient C57BL/6mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31629b8fe14b92073615c99892180cf9
https://doi.org/10.1158/2326-6066.22543822
https://doi.org/10.1158/2326-6066.22543822
Autor:
Lars Roese, Bertolt Kreft, Ilan Vaknin, Gady Cojocaru, Inbal Barbiro, Meir Azulay, Ofer Levy, Zurit Levine, Andrew Drake, Andrew Pow, John Hunter, Anna-Lena Frisk, Helge G. Roider, Sven Golfier, Merlin V. Luetke-Eversloh, Wolf-Dietrich Doecke, Ilona Gutcher, Uwe Gritzan, Julia Huetter
Supplementary information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fe2a0db33965d3dfc6aa1526012afa
https://doi.org/10.1158/2326-6066.22543837.v1
https://doi.org/10.1158/2326-6066.22543837.v1
Autor:
Lars Roese, Bertolt Kreft, Ilan Vaknin, Gady Cojocaru, Inbal Barbiro, Meir Azulay, Ofer Levy, Zurit Levine, Andrew Drake, Andrew Pow, John Hunter, Anna-Lena Frisk, Helge G. Roider, Sven Golfier, Merlin V. Luetke-Eversloh, Wolf-Dietrich Doecke, Ilona Gutcher, Uwe Gritzan, Julia Huetter
Supplementary figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f95813e0e502ffeed2631cf6adb8dc7
https://doi.org/10.1158/2326-6066.22543840.v1
https://doi.org/10.1158/2326-6066.22543840.v1
Autor:
Bertolt Kreft, Karl Ziegelbauer, Rolf Jautelat, Heiner Apeler, Gabriele Leder, Jan Tebbe, Sherif El Sheikh, Rudolf Beier, Frank Dittmer, Jörg Müller, Oliver von Ahsen, Joachim Schuhmacher, Kirk Mclean, Patricia E. Carrigan, Christoph Kneip, Sven Golfier, Claudia Lange, Carol Pena, Beatrix Stelte-Ludwig, Charlotte Kopitz, Hans-Georg Lerchen, Lars Linden, Jörg Willuda
Synthesis of C4.4A-ADC (A), Active metabolites resulting from intracellular degradation of C4.4A-ADC (B), Activity of the C4.4A-ADC metabolites (C), Range of drug-to-antibody ratio (D), and Purity and aggregate content of the ADC (E).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a489a13efac39deb0ca0eac729ae7941
https://doi.org/10.1158/1535-7163.22503556
https://doi.org/10.1158/1535-7163.22503556
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
PDF - 118K, Supplementary Table S1. Mesothelin staining intensity in FFPE tissues of human primary ovarian cancer, pancreatic cancer and mesothelioma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3851a39590f944f943652dd8cf92bb67
https://doi.org/10.1158/1535-7163.22499859
https://doi.org/10.1158/1535-7163.22499859
Autor:
Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner
Effect of BAY 1217389 in monotherapy and combination therapy with paclitaxel on total KNL1 in A2780Cis tumors in nude mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0b68fc1d8f214b0b3e08ca88297410
https://doi.org/10.1158/1535-7163.22508437.v1
https://doi.org/10.1158/1535-7163.22508437.v1
Autor:
Karl Ziegelbauer, Bertolt Kreft, Beate Müller-Tiemann, Frank-Detlef Scholle, Peter Hauff, Axel Harrenga, Lars Linden, Sandra Bruder, Kerstin Unterschemmann, Anke Mayer-Bartschmid, Beatrix Stelte-Ludwig, Christoph A. Schatz, Iring Heisler, Antje Kahnert, Charlotte Kopitz, Sven Golfier
Mesothelin is a tumor differentiation antigen frequently overexpressed in tumors such as mesothelioma, ovarian, pancreatic, and lung adenocarcinomas while showing limited expression in nonmalignant tissues. Mesothelin is therefore an attractive targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95b089c26fcbc4b0cf108dc63a5d571f
https://doi.org/10.1158/1535-7163.c.6536289
https://doi.org/10.1158/1535-7163.c.6536289