Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells.

Autor: Lenoir WF; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Morgado M; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., DeWeirdt PC; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., McLaughlin M; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Griffith AL; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Sangree AK; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Feeley MN; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Esmaeili Anvar N; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kim E; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bertolet LL; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Colic M; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dede M; The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Doench JG; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hart T; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. traver@hart-lab.org.; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. traver@hart-lab.org.

Publikováno v: Nature communications [Nat Commun] 2021 Nov 11; Vol. 12 (1), pp. 6506. Date of Electronic Publication: 2021 Nov 11.

Global analysis of suppressor mutations that rescue human genetic defects.

Autor: Ünlü, Betül¹ (AUTHOR), Pons, Carles² (AUTHOR), Ho, Uyen Linh¹ (AUTHOR), Batté, Amandine¹ (AUTHOR), Aloy, Patrick^2,3 (AUTHOR), van Leeuwen, Jolanda¹ (AUTHOR) jolanda.vanleeuwen@unil.ch

Publikováno v: Genome Medicine. 10/12/2023, Vol. 15 Issue 1, p1-19. 19p.

Optimal construction of a functional interaction network from pooled library CRISPR fitness screens.

Autor: Gheorghe, Veronica^1,2 (AUTHOR), Hart, Traver^1,3 (AUTHOR) traver@hart-lab.org

Publikováno v: BMC Bioinformatics. 11/28/2022, Vol. 22 Issue 10, p1-15. 15p.

CRISPR/Cas9 application in cancer therapy: a pioneering genome editing tool.

Autor: Shojaei Baghini, Sadegh, Gardanova, Zhanna R., Abadi, Saeme Azizi Hassan, Zaman, Burhan Abdullah, İlhan, Ahmet, Shomali, Navid, Adili, Ali, Moghaddar, Roozbeh, Yaseri, Amirhossein Fakhre

Publikováno v: Cellular & Molecular Biology Letters; 5/4/2022, Vol. 27 Issue 1, p1-37, 37p