Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Bertil Hille"'
Autor:
Alexander M Walter, Rainer Müller, Bassam Tawfik, Keimpe DB Wierda, Paulo S Pinheiro, André Nadler, Anthony W McCarthy, Iwona Ziomkiewicz, Martin Kruse, Gregor Reither, Jens Rettig, Martin Lehmann, Volker Haucke, Bertil Hille, Carsten Schultz, Jakob Balslev Sørensen
Publikováno v:
eLife, Vol 6 (2017)
Phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2] is essential for exocytosis. Classical ways of manipulating PI(4,5)P2 levels are slower than its metabolism, making it difficult to distinguish effects of PI(4,5)P2 from those of its metabolites. We d
Externí odkaz:
https://doaj.org/article/aabde6eab85749a18c97c983d851505d
Publikováno v:
eLife, Vol 6 (2017)
CaV-channel dependent activation of BK channels is critical for feedback control of both calcium influx and cell excitability. Here we addressed the functional and spatial interaction between BK and CaV1.3 channels, unique CaV1 channels that activate
Externí odkaz:
https://doaj.org/article/1c0ed96f9e2e4db5ac7c0ced337cab1a
Autor:
Anne E Carlson, Lindsey A Burnett, Donato del Camino, Timothy A Quill, Bertil Hille, Jayhong A Chong, Magdalene M Moran, Donner F Babcock
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6844 (2009)
The four sperm-specific CatSper ion channel proteins are required for hyperactivated motility and male fertility, and for Ca(2+) entry evoked by alkaline depolarization. In the absence of external Ca(2+), Na(+) carries current through CatSper channel
Externí odkaz:
https://doaj.org/article/4d77f98575ee40048360ad16a3b899d8
Autor:
Bertil Hille
Publikováno v:
Prog Biophys Mol Biol
This retrospective traces the hypothesis of ion channels from an early statement in a 1970 essay in this journal (Hille, B., 1970, Prog. Biophys. Mol. Biol. 21, 1–32) to its realization today in biophysical, molecular, biochemical, and structural t
Autor:
Jill B. Jensen, Bjoern H. Falkenburger, Eamonn J. Dickson, Lizbeth de la Cruz, Gucan Dai, Jongyun Myeong, Seung-Ryoung Jung, Martin Kruse, Oscar Vivas, Byung-Chang Suh, Bertil Hille
Publikováno v:
The Journal of general physiology. 154(6)
Phosphoinositide membrane lipids are ubiquitous low-abundance signaling molecules. They direct many physiological processes that involve ion channels, membrane identification, fusion of membrane vesicles, and vesicular endocytosis. Pools of these lip
Autor:
Seung-Ryoung Jung, Kwon-Woo Kim, Byung-Chang Suh, Bertil Hille, Joo Hyun Nam, Woori Ko, Jun-Hee Yeon, Cheon-Gyu Park
Publikováno v:
Proceedings of the National Academy of Sciences. 117:30787-30798
Transmembrane 16A (TMEM16A, anoctamin1), 1 of 10 TMEM16 family proteins, is a Cl- channel activated by intracellular Ca2+ and membrane voltage. This channel is also regulated by the membrane phospholipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)
Autor:
Bertil Hille
Publikováno v:
Annual review of biophysics. 51
Biophysics is a way of approaching biological problems through numbers, physical laws, models, and quantitative logic. In a long scientific career, I have seen the formation and fruition of the ion channel concept through biophysical study. Marvelous
Publikováno v:
Proc Natl Acad Sci U S A
The pineal gland secretes melatonin principally at night. Regulated by norepinephrine released from sympathetic nerve terminals, adrenergic receptors on pinealocytes activate aralkylamine N-acetyltransferase that converts 5-hydroxytryptamine (5-HT, s
Publikováno v:
Proc Natl Acad Sci U S A
β-arrestins regulate many cellular functions including intracellular signaling and desensitization of G protein–coupled receptors (GPCRs). Previous studies show that β-arrestin signaling and receptor endocytosis are modulated by the plasma membra
Publikováno v:
Proceedings of the National Academy of Sciences. 118
β-arrestins regulate many cellular functions including intracellular signaling and desensitization of G protein-coupled receptors (GPCRs). Previous studies show that β-arrestin signaling and receptor endocytosis are modulated by the plasma membrane