Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Berthony Deslouches"'
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/6b2c20580bd9441eadc57f2d2e1b2e83
Autor:
Saheli Mitra, Mark Coopershlyak, Yunshu Li, Bhairavi Chandersekhar, Rachel Koenig, Mei-Tung Chen, Brandt Evans, Frank Heinrich, Berthony Deslouches, Stephanie Tristram-Nagle
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 5, Pp n/a-n/a (2023)
Antibiotics are losing effectiveness as bacteria become resistant to conventional drugs. To find new alternatives, antimicrobial peptides (AMPs) are rationally designed with different lengths, charges, hydrophobicities (H), and hydrophobic moments (
Externí odkaz:
https://doaj.org/article/485b5f3976dc40a7954cfa1c7e3f2dcb
Autor:
Rushikesh Deshpande, Wangyang Li, Tiao Li, Kristen V. Fanning, Zachary Clemens, Toru Nyunoya, Lianghui Zhang, Berthony Deslouches, Aaron Barchowsky, Sally Wenzel, John F. McDyer, Chunbin Zou
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1157 (2024)
The pandemic of coronavirus disease 2019 (COVID-19) has been the foremost modern global public health challenge. The airway is the primary target in severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) infection, with substantial cel
Externí odkaz:
https://doaj.org/article/5ceec47442a84996a8335b9b8b92f88a
Autor:
Wenyu Xiang, Patrice Clemenza, Jessie Klousnitzer, Jespar Chen, Weiheng Qin, Stephanie Tristram-Nagle, Yohei Doi, Y. Peter Di, Berthony Deslouches
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The threat of antibiotic resistance warrants the discovery of agents with novel antimicrobial mechanisms. Antimicrobial peptides (AMPs) directly disrupting bacterial membranes may overcome resistance to traditional antibiotics. AMP development for cl
Externí odkaz:
https://doaj.org/article/609951ce00f9461daa7345404a47a07c
Autor:
Jonathan B. Mandell, Berthony Deslouches, Ronald C. Montelaro, Robert M. Q. Shanks, Yohei Doi, Kenneth L. Urish
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Antibiotics are unable to remove biofilms from surgical implants. This high antibiotic tolerance is related to bacterial persisters, a sub-population of bacteria phenotypically tolerant to antibiotics secondary to a reduced metabolic state.
Externí odkaz:
https://doaj.org/article/cb3d0718c264403fae93484e9e97d3c0
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Multidrug resistance (MDR) by bacterial pathogens constitutes a global health crisis, and resistance to treatment displayed by biofilm-associated infections (e.g., cystic fibrosis, surgical sites, and medical implants) only exacerbates a pro
Externí odkaz:
https://doaj.org/article/98859e73258d4f9b92d5c797ed1383d8
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 501 (2020)
The increasing rate of antibiotic resistance constitutes a global health crisis. Antimicrobial peptides (AMPs) have the property to selectively kill bacteria regardless of resistance to traditional antibiotics. However, several challenges (e.g., redu
Externí odkaz:
https://doaj.org/article/22c468f2a1e74d199282d4c5b4fa6739
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203621 (2018)
SPLUNC1 is a multifunctional protein of the airway with antimicrobial properties. We previously reported that it displayed antibiofilm activities against P. aeruginosa. The goal of this study was to determine whether (1) the antibiofilm property is b
Externí odkaz:
https://doaj.org/article/30238aa73dd645489098a86c20b01ddb
Autor:
Jeffrey A. Melvin, Lauren P. Lashua, Megan R. Kiedrowski, Guanyi Yang, Berthony Deslouches, Ronald C. Montelaro, Jennifer M. Bomberger
Publikováno v:
mSphere, Vol 1, Iss 3 (2016)
ABSTRACT Antimicrobial-resistant infections are an urgent public health threat, and development of novel antimicrobial therapies has been painstakingly slow. Polymicrobial infections are increasingly recognized as a significant source of severe disea
Externí odkaz:
https://doaj.org/article/60146e0eeb594e39abdaf580efee2efc
Publikováno v:
Current Microbiology. 80