Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Berthold Lausecker"'
Autor:
Gérard Hopfgartner, Manfred Zell, Christophe Husser, Annemarie Maschka-Selig, Berthold Lausecker
Publikováno v:
CHIMIA, Vol 53, Iss 10 (1999)
HPLC coupled to atmospheric pressure ionisation mass spectrometry has almost replaced HPLC assays with UV, fluorescence, or electrochemical detection, due to its enhanced speed, sensitivity, and selectivity, especially when tandem-MS is used. To incr
Externí odkaz:
https://doaj.org/article/4a31b567ca5e43a8b570edf2c62c88aa
Publikováno v:
Clinical Pharmacokinetics. 52:463-473
Human mass balance studies and the assessment of absolute oral bioavailability (F) are usually assessed in separate studies. Intravenous microdose administration of an isotope tracer concomitant to an unlabeled oral dose is an emerging technique to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51604af1eee84143189d21fbd6bd1bce
https://doi.org/10.1007/s40262-013-0051-z
https://doi.org/10.1007/s40262-013-0051-z
Autor:
Philip Timmerman, Marianne Scheel-Fjording, Bruno Le Bras, Alberto Guenzi, Stephen White, Daniel Neddermann, Berthold Lausecker, Susanne Globig, Marcel de Zwart
Publikováno v:
Bioanalysis. 8(19)
Interference testing of co-medication in bioanalytical method validation has become an area of debate in view of the increased specificity offered by current state-of-the-art technology in both LC–MS/MS and ligand-binding assay platforms. In view o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d63f0137ad7400754c091bf0ac7ca0
https://pubmed.ncbi.nlm.nih.gov/27416776
https://pubmed.ncbi.nlm.nih.gov/27416776
Autor:
Begona Barosso, Dijksman Jessica A R, Peter van Amsterdam, Silke Luedtke, Berthold Lausecker, Philip Timmerman
Publikováno v:
Bioanalysis. 4:627-631
This conference report provides an overview of the discussions at the 2nd European Bioanalysis Forum (EBF) Focus Meeting ‘Large Meets Small’ held on 20 and 21 June 2011 in Brussels. The meeting discussed scientific progress in the bioanalysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d34f66185c888c933d3bd6280cf2cfc
https://doi.org/10.4155/bio.12.37
https://doi.org/10.4155/bio.12.37
Autor:
Peter van Amsterdam, John Smeraglia, Berthold Lausecker, Susanne Globig, Fernando Romero, Michaela Golob, Christian Herling, Ben Gordon, Philip Timmerman, Magnus Knutsson, Eva Vieser, Margarete Brudny-Kloeppel, Richard Abbott
Publikováno v:
Bioanalysis. 3:833-838
The European Bioanalysis Forum is a bioanalytical nonprofit organization comprised of European pharmaceutical companies (27 members to date) and currently expanding to include CROs as well. The European Bioanalysis Forum provides a broad European bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b64563985e57d5fd6e9d89bfae32af
https://doi.org/10.4155/bio.11.52
https://doi.org/10.4155/bio.11.52
Autor:
Carl Johan Sennbro, Sirpa Laakso, Dietmar Schmidt, Josep Maria Jansat, Achim Freisleben, Hans Mulder, Marcel de Zwart, Pierre Boulanger, Michael P. Andersen, Elizabeth Thomas, Stephanie Fischmann, Nathalie Mokrzycki-Issartel, Dirk Kasel, Morten A. Kall, Philip Timmerman, Richard Hucker, Fernando Romero, Stephen White, Berthold Lausecker, Susanne Globig, Silke Luedtke, Ben Gordon, Norbert Knebel, Peter van Amsterdam, Magnus Knutsson, Richard Abbott, Margarete Brudny-Kloeppel
Publikováno v:
Bioanalysis. 1:1049-1056
Following intensive discussions, review, alignment of procedures and multiple surveys among their member companies, the European Bioanalysis Forum (EBF) is providing a recommendation on how to integrate incurred sample reproducibility (ISR) in the bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa4ffdcc3f974793c4b309ee40e420d
https://doi.org/10.4155/bio.09.108
https://doi.org/10.4155/bio.09.108
Autor:
Fabrice Salavert, Jeff Long, Timothy Sangster, Neil Adcock, Walid Elbast, Stuart McDougall, Stephen White, Peter van Amsterdam, Berthold Lausecker, Magnus Knutsson, Jim Hiller, Tom Verhaeghe
Publikováno v:
Bioanalysis. 6(20)
Adequate monitoring of internal standard (IS) response across an analytical run and identification of anomalies is now a common expectation. However, the means to conduct this assessment in an appropriate manner is unclear and differs widely between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3593804dab1752504107bac1a9f97318
https://pubmed.ncbi.nlm.nih.gov/25413707
https://pubmed.ncbi.nlm.nih.gov/25413707
Autor:
Douglas M. Fast, Berthold Lausecker, Roger Hayes, Noriko Inoue, Maria Francesca Riccio, John A. Dunn, Junji Komaba, Barbara Duncan, Christopher L Holliman, Ben Gordon, Katja Heinig, Stuart McDougall, Richard LeLacheur, Hollie H. Barton, Raymond Farmen, Amy Flynn, Kazutaka Togashi, Eric Woolf, Abhishek Sharma, Maristela Andraus, Miguel Vago, Michael Blackburn, Matthew Barfield, Ravi Kumar Trivedi, David W. Hoffman, Elizabeth Thomas, Scott Reuschel, Stephen White, Ravisankar Santhanam, Gabriel Marcelin-Jimenez, Patrick Bennett
Publikováno v:
The AAPS journal. 16(5)
Consensus practices and regulatory guidance for liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) assays of small molecules are more aligned globally than for any of the other bioanalytical techniques addressed by the Global Bioana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0324973269ce84d0e912f269585cc34e
https://pubmed.ncbi.nlm.nih.gov/24961918
https://pubmed.ncbi.nlm.nih.gov/24961918
Autor:
Margarete Brudny-Kloeppel, Peter van Amsterdam, Silke Luedtke, Berthold Lausecker, Philip Timmerman
Publikováno v:
Bioanalysis. 2:689-691
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57f0ac8227dd518902c17cce5283481
https://doi.org/10.4155/bio.10.37
https://doi.org/10.4155/bio.10.37
Autor:
Samuel J. Machin, Herbert Birnböck, Bärbel Wittke, Jain Chung, Ian Mackie, Hilary Ensor, Sylvie I. Ertel, Berthold Lausecker
Publikováno v:
British Journal of Clinical Pharmacology. 49:231-239
Aims The purpose of this clinical study was to evaluate the effects of a ticlopidine/aspirin combination on the pharmacokinetics and pharmacodynamics of sibrafiban and the tolerability of the combination therapy Methods Thirty-eight healthy male volu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6605514dd1ade17a3bde70839940b7ec
https://doi.org/10.1046/j.1365-2125.2000.049003231.x
https://doi.org/10.1046/j.1365-2125.2000.049003231.x