Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Berthold Hinzen"'
Autor:
Imran Malik, Helga Ruebsamen-Schaeff, Heike Brötz-Oesterhelt, Peter Sass, Berthold Hinzen, Marina Alber, Kirsten Famulla, Rainer Kalscheuer, Alfred L. Goldberg, Olga Kandror, Tatos Akopian
Publikováno v:
Molecular microbiology. 101(2)
The Clp protease complex in Mycobacterium tuberculosis is unusual in its composition, functional importance, and activation mechanism. While most bacterial species contain a single ClpP protein that is dispensable for normal growth, mycobacteria have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7623ecdbdb11a50e86e723ba6c273f63
https://pubmed.ncbi.nlm.nih.gov/27000447
https://pubmed.ncbi.nlm.nih.gov/27000447
Autor:
Berthold Hinzen, Jörg Keldenich, Mario Lobell, Alexander Hillisch, Heinrich Meier, Carsten Schmeck, Rudolf Schohe-Loop, Tobias Wunberg, Martin Hendrix
Publikováno v:
ChemMedChem. 1:1229-1236
The need for in silico characterization of HTS hit structures as part of a data-driven hit-selection process is demonstrated. A solution is described in the form of an in silico ADMET traffic light and PhysChem scoring system. This has been extensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e39e40e19cd15f12b698460890db57
https://doi.org/10.1002/cmdc.200600168
https://doi.org/10.1002/cmdc.200600168
Publikováno v:
Angewandte Chemie. 118:5194-5254
Zur Entwicklung von Medikamenten mussen die Strukturvorlagen aus der Natur oft durch Semisynthese oder Totalsynthese verbessert werden (chemische Post-Evolution). Der Weg vom Naturstoff zum Arzneimittel ist muhsam aber lohnenswert. Die grundlegenden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3869a01a285030585a6718d59d9fab1
https://doi.org/10.1002/ange.200600350
https://doi.org/10.1002/ange.200600350
Autor:
Harald Labischinski, Jordi Benet-Buchholz, Dieter Habich, Veronica Hellwig, Andreas Schumacher, Heike Brötz-Oesterhelt, Rainer Endermann, Berthold Hinzen, Thomas Lampe, Holger Paulsen, Siegfried Raddatz
Publikováno v:
ChemMedChem. 1:689-693
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca61327479c60f1995db1ffd4fd36e0c
https://doi.org/10.1002/cmdc.200600055
https://doi.org/10.1002/cmdc.200600055
Autor:
Michael G. Hahn, Berthold Hinzen
Publikováno v:
Combinatorial Chemistry: From Theory to Application, Volume 26, Second Revised Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468994af12857ec9b8331920bb768e98
https://doi.org/10.1002/3527607706.ch6
https://doi.org/10.1002/3527607706.ch6
Autor:
Berthold Hinzen
Publikováno v:
Combinatorial Chemistry: From Theory to Application, Volume 26, Second Revised Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459877b37cb904c9879e5572aa0ebee4
https://doi.org/10.1002/3527607706.ch7
https://doi.org/10.1002/3527607706.ch7
Autor:
Berthold Hinzen, Johannes Köbberling
Publikováno v:
Combinatorial Chemistry: From Theory to Application, Volume 26, Second Revised Edition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1b8749fb870383fc2f806d4ff0115f
https://doi.org/10.1002/3527607706.app1
https://doi.org/10.1002/3527607706.app1
Autor:
Luke G. Green, Berthold Hinzen, Daniel K. Baeschlin, Steven V. Ley, Michael G. Hahn, Stuart J. Ince
Publikováno v:
Tetrahedron: Asymmetry. 11:173-197
This paper describes the application of 1,2-diacetal protecting groups to control the reactivity tuning of glycosyl fluorides in oligosaccharide coupling reactions. The synthetic potential of this new methodology is demonstrated by the ‘one-pot’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c2c8271f3eaa981d88014766c51a612
https://doi.org/10.1016/s0957-4166(99)00519-4
https://doi.org/10.1016/s0957-4166(99)00519-4
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2239-2242
The automated sequential application of polymer supported perruthenate (PSP) and polymer supported cyanoborohydride (PSCBH) in an oxidation–reductive amination procedure allowed the efficient transformation of simple alcohols into more complex amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf2781172242c743b5df008b129f99ed
https://doi.org/10.1039/a803611j
https://doi.org/10.1039/a803611j
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2235-2238
Nafion-TMS mediated Mukaiyama aldol reaction of silyl enol ethers with aldehydes, obtained from mild oxidation of alcohols with polymer supported perruthenate (PSP), yielded α,β-unsaturated ketones, which upon treatment with hydrazines allowed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4679d9383a593b18539c4fd861860689
https://doi.org/10.1039/a803609h
https://doi.org/10.1039/a803609h