Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques.

Autor: Nazanin Hakimzadeh, Victorine A Pinas, Ger Molenaar, Vivian de Waard, Esther Lutgens, Berthe L F van Eck-Smit, Kora de Bruin, Jan J Piek, Jos L H Eersels, Jan Booij, Hein J Verberne, Albert D Windhorst

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0187767 (2017)

Molecular imaging of matrix metalloproteinases (MMPs) may allow detection of atherosclerotic lesions vulnerable to rupture. In this study, we develop a novel radiolabelled compound that can target gelatinase MMP subtypes (MMP2/9) with high selectivit

Externí odkaz: https://doaj.org/article/7454f27022434d52ba4e7bbfe447ddc7

Monocyte scintigraphy in rheumatoid arthritis: the dynamics of monocyte migration in immune-mediated inflammatory disease.

Autor: Rogier M Thurlings, Carla A Wijbrandts, Roelof J Bennink, Serge E Dohmen, Carlijn Voermans, Diana Wouters, Elena S Izmailova, Danielle M Gerlag, Berthe L F van Eck-Smit, Paul P Tak

Publikováno v: PLoS ONE, Vol 4, Iss 11, p e7865 (2009)

BACKGROUND:Macrophages are principal drivers of synovial inflammation in rheumatoid arthritis (RA), a prototype immune-mediated inflammatory disease. Conceivably, synovial macrophages are continuously replaced by circulating monocytes in RA. Animal s

Externí odkaz: https://doaj.org/article/108998e3fb694a348817b308776b4d26

[18F]FDG-PET or PET/CT in the evaluation of pelvic and para-aortic lymph nodes in patients with locally advanced cervical cancer: A systematic review of the literature

Autor: Judit A. Adam, Berthe L. F. van Eck-Smit, Constantijne H. Mom, Jaap Stoker, Shandra Bipat, Pascal R. van Diepen

Publikováno v: Adam, J A, van Diepen, P R, Mom, C H, Stoker, J, van Eck-Smit, B L F & Bipat, S 2020, ' [ 18 F]FDG-PET or PET/CT in the evaluation of pelvic and para-aortic lymph nodes in patients with locally advanced cervical cancer: A systematic review of the literature ', Gynecologic Oncology, vol. 159, no. 2, pp. 588-596 . https://doi.org/10.1016/j.ygyno.2020.08.021
Gynecologic oncology, 159(2), 588-596. Academic Press Inc.

Purpose: Imaging is essential in detecting lymph node metastases for radiotherapy treatment planning in locally advanced cervical cancer (LACC). There are not many data on the performance of [ 18F]FDG-PET(CT) in showing lymph node metastases in LACC.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd065fddc6e9e486c79d5f4b373a9faf
http://www.scopus.com/inward/record.url?scp=85090580331&partnerID=8YFLogxK

18F-FDG-PET/CT guided external beam radiotherapy volumes in inoperable uterine cervical cancer

Autor: Jan H van Waesberghe, Constantijne H. Mom, Rob M. van Os, Hester Arkies, Karel Hinnen, Jaap Stoker, Berthe L. F. van Eck-Smit, J.J. Laan, Judit A. Adam, Lukas J.A. Stalpers

Publikováno v: The Quarterly Journal of Nuclear Medicine and Molecular Imaging, 62(4), 420-428. Edizioni Minerva Medica S.p.A.
quarterly journal of nuclear medicine and molecular imaging, 62(4), 420-428. Edizioni Minerva Medica S.p.A.
Adam, J A, Arkies, H, Hinnen, K, Stalpers, L J, van Waesberghe, J H, Stoker, J, van Os, R, Laan, J J, Mom, C H & van Eck-Smit, B L 2018, ' 18F-FDG-PET/CT guided external beam radiotherapy volumes in inoperable uterine cervical cancer ', The Quarterly Journal of Nuclear Medicine and Molecular Imaging, vol. 62, no. 4, pp. 420-428 . https://doi.org/10.23736/S1824-4785.18.03083-2

BACKGROUND: In patients with advanced stage cancer of the uterine cervix who undergo irradiation with curative intent, there is the necessity to treat all suspicious nodes on imaging. Our hypothesis was that adding fluorodeoxyglucose positron emissio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e041f070cf48db44183a9c23f080764
https://research.vumc.nl/en/publications/781698cb-e96e-4a7f-af00-0258cb0ddb8b

Assessment of 123I-mIBG and 99mTc-tetrofosmin single-photon emission computed tomographic images for the prediction of arrhythmic events in patients with ischemic heart failure: Intermediate severity innervation defects are associated with higher arrhythmic risk

Autor: Mark I. Travin, Diwakar Jain, Russell D. Folks, Arnold F. Jacobson, Ernest V. Garcia, Berthe L. F. van Eck-Smit, Hein J. Verberne, Milena J. Henzlova, Ignasi Carrió

Publikováno v: Journal of Nuclear Cardiology. 24:377-391

123I-mIBG planar image heart-to-mediastinum ratios effectively risk-stratify heart failure (HF) patients. The value of single-photon emission computed tomographic (SPECT) imaging for identifying increased risk of ventricular arrhythmias is less clear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd4ac7461a89bc8a9b0e4ff05ff78b09
https://doi.org/10.1007/s12350-015-0336-8