Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Berthe Fournier"'
Publikováno v:
Journal of Cardiovascular Pharmacology. 39:98-106
The aim of this study was to determine in spontaneously hypertensive rats (SHRs) whether a significant association may be observed between the low-frequency component of blood pressure variability (BPV) and arterial distensibility and to evaluate the
Autor:
Berthe Fournier, Stéphane Laurent, Michel E. Safar, Hubert Dabiré, Kamel Chaouche-Teyara, Patrick Lacolley, Pascal Challande
Publikováno v:
Journal of Cardiovascular Pharmacology. 30:241-244
Summary: The effects of two centrally acting antihypertensive agents, clonidine (0.1 mg/kg/day s.c.) and flesinoxan (1 mg/kg/day s.c.), on short-term blood pressure variability (BPV) were investigated in conscious spontaneously hypertensive rats (SHR
Publikováno v:
Clinical and Experimental Hypertension. 16:779-798
The present experiment was performed to investigate the haemodynamic effects of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and alpha-methyl-5-hydroxytryptamine (alpha-methyl-5-HT) in the anaesthetised normotensive rat. DOI (1-300 micrograms/
Publikováno v:
European Journal of Pharmacology. 250:67-75
In pithed rats, alpha-methyl-5-hydroxytryptamine (alpha-methyl-5-HT) increased blood pressure and heart rate, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) almost exclusively increased blood pressure and 1-(3-chlorophenyl)piperazine (mCPP), hea
Publikováno v:
Clinical and experimental pharmacologyphysiology. 27(9)
SUMMARY 1. Hypertensive conduit arteries are thicker and stiffer than those of normotensive controls. Whether they are specifically sensitive to central sympathoinhibition has never been investigated. 2. The effects of acute (24 h infusion) and chron
Publikováno v:
Fundamentalclinical pharmacology. 6(6)
A pharmacological analysis of the effects of 5-HT on heart rate has been performed in the pithed rat. 5-HT induced a dose-dependent increase in heart rate whereas 5-HT1 receptor agonists--8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), 5-methoxy-
Autor:
Bajjou R, Hubert Dabiré, De Nanteuil G, Michel Laubie, Berthe Fournier, Henri Schmitt, Michel E. Safar, Kamel Chaouche-Teyara
Publikováno v:
European Journal of Pharmacology. 203:323-324
Publikováno v:
European Journal of Pharmacology. 73:367-370
(Imidazolyl-2)-2-benzodioxane 1–4 (170 150) has been shown to possess α2-adrenoceptor blocking properties. The present investigation attempted to further characterize the α2-adrenoceptor blocking effect of 170 150. In pithed rats, 170 150 did not
Publikováno v:
European journal of pharmacology. 140(3)
The present experiments served to compare the effects of the 3 5-HT1 agonists, 8-OH-DPAT, 5-MeODMT and TFMPP on the blood pressure and heart rate of normotensive anaesthetized rats. All the agonists induced, after i.v. injection, a decrease in blood
Autor:
Hubert Dabiré, Cherqui C, Henri Schmitt, Michel Laubie, Kamel Chaouche-Teyara, Berthe Fournier
Publikováno v:
European journal of pharmacology. 168(3)
DOI (1–100 μg/kg i.v.) induced an increase in mean blood pressure in the anaesthetized rat. Similarly, in the pithed rat, DOI (1–100 μg/kg i.v.) induced a dose-dependent increase in mean blood pressure, as did 5-HT. However, in contrast to 5-HT