Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Bertha K. Madras"'
Autor:
Marie-Eve Di Raddo, Marija Milenkovic, Meenalochani Sivasubramanian, Ahmed Hasbi, Jack Bergman, Sarah Withey, Bertha K. Madras, Susan R. George
Publikováno v:
Current Research in Neurobiology, Vol 5, Iss , Pp 100107- (2023)
Earlier age of cannabis usage poses higher risk of Cannabis Use Disorder and adverse consequences, such as addiction, anxiety, dysphoria, psychosis, largely attributed to its principal psychoactive component, Δ9-tetrahydrocannabinol (THC) and altere
Externí odkaz:
https://doaj.org/article/5183b3c0623a4efebc0e30d59c8a9535
Autor:
Ahmed Hasbi, Tuan Nguyen, Haneen Rahal, Joshua D. Manduca, Sharon Miksys, Rachel F. Tyndale, Bertha K. Madras, Melissa L. Perreault, Susan R. George
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Depression and anxiety are more common among females than males and represent a leading cause of disease-related disability in women. Since the dopamine D1-D2 heteromer is involved in depression- and anxiety-like behavior, the possibility th
Externí odkaz:
https://doaj.org/article/3298301a82ff4b089393019ba22e13bd
Publikováno v:
Brain Sciences, Vol 13, Iss 2, p 325 (2023)
Background: There is a growing liberalization of cannabis-based preparations for medical and recreational use. In multiple instances, anxiety and depression are cited as either a primary or a secondary reason for the use of cannabinoids. Aim: The pur
Externí odkaz:
https://doaj.org/article/3c0ad8e77b9d4c8b8e2ae52b677354b4
Autor:
Ahmed Hasbi, Meenalochani Sivasubramanian, Marija Milenkovic, Kristina Komarek, Bertha K. Madras, Susan R. George
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 105017- (2020)
Background: Dopamine receptors interact with other receptors to form heterooligomers. One such complex, the D1-D2 heteromer, demonstrated in cultured striatal neurons and rat striatum has been linked to drug addiction, Parkinson's disease, schizophre
Externí odkaz:
https://doaj.org/article/c5ad617b32544ea7850acd2b715b454f
Autor:
Ahmed Hasbi, Bertha K. Madras, Jack Bergman, Stephen Kohut, Zhicheng Lin, Sarah L. Withey, Susan R. George
Publikováno v:
iScience, Vol 23, Iss 1, Pp - (2020)
Summary: Long-term cannabis users manifest deficits in dopaminergic functions, reflecting Δ9-tetrahydrocannabinol (THC)-induced neuroadaptive dysfunctional dopamine signaling, similar to those observed upon dopamine D1-D2 heteromer activation. The m
Externí odkaz:
https://doaj.org/article/53afb47122854d4e99b4dfbe6d4c3e13
Autor:
James M. Schumacher, Philippe Hantraye, Anna-Lisa Brownell, Danielle Riche, Bertha K. Madras, Paula D. Davenport, Mariannick Maziere, David R. Elmaleh, Gordon L. Brownell, Ole Isacson
Publikováno v:
Cell Transplantation, Vol 1 (1992)
In this article, we show that 1) computed tomographic (CT)-guided stereotactic infusion of an excitotoxin into the striatum of a nonhuman primate provides a useful neuropathologic and behavioral model for Huntington's disease. 2) High-resolution posi
Externí odkaz:
https://doaj.org/article/51db233d8e6741e188574aef3dcc0027
Autor:
Bertha K. Madras
Publikováno v:
The New England journal of medicine. 387(18)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250446e7e097818daa378a964aa5d431
https://pubmed.ncbi.nlm.nih.gov/36322843
https://pubmed.ncbi.nlm.nih.gov/36322843
Publikováno v:
Biological Psychiatry Global Open Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beced646ea148fb47f7d9941f347f0da
https://doi.org/10.1016/j.bpsgos.2022.07.003
https://doi.org/10.1016/j.bpsgos.2022.07.003
Publikováno v:
Trends in Pharmacological Sciences. 39:995-998
The United States is experiencing an epidemic of opioid overdose deaths. Many of the recent fatalities are associated with illicitly manufactured fentanyl, which is being added to heroin and counterfeit pain pills. The crisis is further exacerbated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec86142f63d544567cd9375261918dcb
https://doi.org/10.1016/j.tips.2018.09.006
https://doi.org/10.1016/j.tips.2018.09.006
Autor:
Sarah L, Withey, Brian D, Kangas, Sophia, Charles, Andrew B, Gumbert, Jessica E, Eisold, Susan R, George, Jack, Bergman, Bertha K, Madras
Publikováno v:
Drug Alcohol Depend
BACKGROUND: Daily use of marijuana is rising in adolescents, along with consumption of high potency marijuana products (high % Δ−9-tetrahydrocannabinol or THC). These dual, related trends have opened gaps in understanding the long-term effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b84755bc15f7bafa680edad7163a28ac
https://pubmed.ncbi.nlm.nih.gov/33640678
https://pubmed.ncbi.nlm.nih.gov/33640678