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Comparative analysis ofp53 gene mutations and protein accumulation in human non-small-cell lung cancer

Autor: Siegina G. Klaver, Lucie Boerrigter, Sjoerd Visser, Sjoerd Rodenhuis, Peter Wisman, Bert Top, Hans R. J. Elbers, Wolter J. Mooi

Publikováno v: International Journal of Cancer. 64:83-91

A series of 54 resected primary non-small-cell lung carcinomas was analyzed for p53 gene mutations and for p53 protein accumulation and the findings were correlated with clinical parameters. Mutations in exons 5 through 8 of the p53 gene were identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3605a046390bf9e42c60d58eb4902c6
https://doi.org/10.1002/ijc.2910640203

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Akademický článek

面向功能语义增强与标签关联的 Web 服务标签推荐.

Autor: 刘庆雪¹ huqiang200280@163.com, 王荔芳¹, 潘国庆^1,2, 胡强²

Publikováno v: Application Research of Computers / Jisuanji Yingyong Yanjiu. Sep2024, Vol. 41 Issue 9, p2678-2684. 7p.

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Poly[d(C-A)]�poly[d(G-T)] is highly transcribed in the testes of Drosophila hydei

Autor: Richard J. Sinke, Luc Beckers, Peter Huijser, Bert Top, Monique M.P. Hermans, Wolfgang Hennig

Publikováno v: Chromosoma, 100(1), 48-55

Microdissection of the lampbrush loops "threads" and "pseudonucleolus" of Y chromosomes from primary spermatocytes of Drosophila hydei and subsequent microcloning of the DNA yielded several recombinant DNA clones which cross-hybridized in screening t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdcee765a1903d220f9539fd09d31ea
https://doi.org/10.1007/bf00337602

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Evaluation of a new method for early detection of active cytomegalovirus infections. A study in kidney transplant recipients

Autor: M. H. L. Christiaans, Marinus J. Blok, Valère J. Goossens, J.P. van Hooff, Cathrien A. Bruggeman, Bert Top, Jaap M. Middeldorp

Publikováno v: Transplant International, 11 Suppl 1, S107-9. Wiley-Blackwell
Blok, M J, Christiaans, M H, Goossens, V J, van Hooff, J P, Top, B, Middeldorp, J M & Bruggeman, C A 1998, ' Evaluation of a new method for early detection of active cytomegalovirus infections. A study in kidney transplant recipients ', Transplant International, vol. 11 Suppl 1, pp. S107-9 .

Early detection of active cytomegalovirus (CMV) infection after organ transplantation is necessary to start effective antiviral treatment. In the present study, blood specimens of kidney transplant recipients (n = 38) were monitored for the expressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f771a88258ca9611f7b6d50434cf2c7
https://doi.org/10.1007/s001470050439

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Association of H-ras mutations with adenocarcinomas of the parotid gland

Autor: H.K. van Halteren, Wolter J. Mooi, Alfons J. M. Balm, Bert Top, Sjoerd Rodenhuis

Publikováno v: International journal of cancer. Journal international du cancer, 57(3), 362-364. Wiley-Liss Inc.

We have examined 17 adenocarcinomas and 2 mixed tumors of the salivary glands for mutational activation of the oncogenes H-ras, K-ras and N-ras. The presence of mutations was determined by in vitro amplification of gene fragments spanning codons 12,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e50a2c0869384fb80ef8176d72f53e8
https://doi.org/10.1002/ijc.2910570312

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Nucleic acid sequence-based amplification (NASBA) detection of medically important Candida species

Autor: Annemarie Borst, R Schukkink, Nicole M. M. Tacken, Adrienne T.A. Box, Ad C. Fluit, Bob van Gemen, Jan Verhoef, M. N. Widjojoatmodjo, Bert Top

Publikováno v: Journal of microbiological methods. 38(1-2)

Nucleic Acid Sequence Based Amplification (iNASBA), an isothermal amplification technique for nucleic acids, was evaluated for the identification of medically important Candida species using primers selected from 18S rRNA sequences conserved in fungi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba6ce1c4eacb0af8e6f6b0e41f95f8b
https://pubmed.ncbi.nlm.nih.gov/10520588

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Highly sensitive detection of gene expression of an intronless gene: amplification of mRNA, but not genomic DNA by nucleic acid sequence based amplification (NASBA)

Autor: Bert Top, Albert Heim, Stefanie Zeuke, Isabella M. Grumbach

Publikováno v: Nucleic acids research. 26(9)

NASBA is an isothermal nucleic acid amplification reaction that amplifies mRNA in a dsDNA background. Although similar to the sensitive reverse transcription/polymerase chain reaction (RT-PCR) in mRNA detection, NASBA is not prone to give false posit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0aa94712d35da68bfb572d4337b8ec
https://pubmed.ncbi.nlm.nih.gov/9547289

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Diagnostic value of monitoring human cytomegalovirus late pp67 mRNA expression in renal-allograft recipients by nucleic acid sequence-based amplification

Autor: Valère J. Goossens, Bert Top, Maarten H. L. Christiaans, Sabina J. V. Vanherle, Nicole M. M. Tacken, Cathrien A. Bruggeman, Jaap M. Middeldorp, Johannes P. van Hooff, Marinus J. Blok

Publikováno v: Journal of Clinical Microbiology, 36(5), 1341-6. American Society for Microbiology
Journal of Clinical Microbiology, 36(5), 1341-1346. American Society for Microbiology
Europe PubMed Central
Blok, M J, Goossens, V J, Vanherle, S J, Top, B, Tacken, N, Middeldorp, J M, Christiaans, M H, van Hooff, J P & Bruggeman, C A 1998, ' Diagnostic value of monitoring human cytomegalovirus late pp67 mRNA expression in renal-allograft recipients by nucleic acid sequence-based amplification ', Journal of Clinical Microbiology, vol. 36, no. 5, pp. 1341-6 .

Department of Medical Microbiology, University Hospital Maastricht, The Netherlands. mbl@lmib.azm.nlThe diagnostic value of monitoring human cytomegalovirus (HCMV) late pp67 mRNA expression by nucleic acid sequence-based amplification (NASBA) after r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337fe4055dda49241e2e94e9a26057c3
https://research.vumc.nl/en/publications/d92ac01c-5b6b-45f5-ac7c-d7edb169b939

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