Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bert Oehlen"'
Autor:
Lee Arnold, Gregg G. Gundersen, Bert Oehlen, I. Bernard Weinstein, Atsuko Deguchi, Danhua Xiao
Publikováno v:
Molecular Cancer Therapeutics. 5:60-67
Exisulind (sulindac sulfone) and three highly potent derivatives, OSI-461 (CP461), OSIP486823 (CP248), and OSIP487703, inhibit growth and induce apoptosis in SW480 human colon cancer cells, with IC50s of 200, 2, 0.1, and 0.003 μmol/L, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895003b4336acc0b78f22107aec7253a
https://doi.org/10.1158/1535-7163.mct-05-0260
https://doi.org/10.1158/1535-7163.mct-05-0260
Publikováno v:
Journal of Biological Chemistry. 277:6881-6887
The ability of G protein-coupled receptors (GPCRs) to form homo- and heteromeric complexes has important implications for the regulation of cellular events. A notable example of heteromer formation is the interaction of the calcitonin receptor-like r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d318b2aaa59350a1b7cc90cf4236ab
https://doi.org/10.1074/jbc.m107384200
https://doi.org/10.1074/jbc.m107384200
Autor:
Bert Oehlen, Frederick R. Cross
Publikováno v:
Current Opinion in Cell Biology. 6:836-841
As a key part of the mechanism which controls growth and division, cells are able to respond to a variety of intracellular and extracellular stimuli. Significant progress has been made in the understanding of the biochemical mechanisms underlying mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9633840440ea7d68b5259f951836eaac
https://doi.org/10.1016/0955-0674(94)90053-1
https://doi.org/10.1016/0955-0674(94)90053-1
Autor:
Dong Sung Lim, Gaifeng Ma, Itzhak D. Goldberg, Jim Tarrant, Bijoy Panicker, Xiaokang Zhu, Siobhan McCormack, Bert Oehlen
Publikováno v:
Molecular Cancer Therapeutics. 12:B257-B257
Retinoids, such as the prototypical retinoid all trans retinoic acid (ATRA), have been used successfully in the treatment of acute promyelocytic leukemia (APL) patients. They have also been tested for efficacy in solid tumors, including breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63a56abcb4fd6b9ca9b6cd7912dc4e63
https://doi.org/10.1158/1535-7163.targ-13-b257
https://doi.org/10.1158/1535-7163.targ-13-b257
Autor:
Itzhak D. Goldberg, Bijoy Panicker, Gaifeng Ma, Siobhan McCormack, Bert Oehlen, Dong Sung Lim
Publikováno v:
Cancer Research. 73:5560-5560
Prostate cancer affects 1 in 6 men and is the second most common cause of cancer-related death. Since the majority of prostate cancers critically depend on androgens for growth, androgen deprivation therapy is a frontline treatment for advanced prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdd0a534db9524d579aae393af870da6
https://doi.org/10.1158/1538-7445.am2013-5560
https://doi.org/10.1158/1538-7445.am2013-5560