Maternal Western-style high fat diet induces sex-specific physiological and molecular changes in two-week-old mouse offspring.

Autor: Mona Mischke, Maurien G M Pruis, Mark V Boekschoten, Albert K Groen, Aditia R Fitri, Bert J M van de Heijning, Henkjan J Verkade, Michael Müller, Torsten Plösch, Wilma T Steegenga

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e78623 (2013)

Maternal diet is associated with the development of metabolism-related and other non-communicable diseases in offspring. Underlying mechanisms, functional profiles, and molecular markers are only starting to be revealed. Here, we explored the physiol

Externí odkaz: https://doaj.org/article/490d0971714a4afa9eccaa23026f1a5a

Long-term effects of a modified, low-protein infant formula on growth and body composition

Autor: Martijn J J Finken, Eline M. van der Beek, Stefanie M.P. Kouwenhoven, Bert J. M. van de Heijning, Berthold Koletzko, Jos W. R. Twisk, Marieke Abrahamse-Berkeveld, Nadja Antl, Johannes B. van Goudoever

Publikováno v: Clinical Nutrition, 40(6), 3914-3921. Churchill Livingstone
Kouwenhoven, S M P, Antl, N, Finken, M J J, Twisk, J W R, van der Beek, E M, Abrahamse-Berkeveld, M, van de Heijning, B J M, van Goudoever, J B & Koletzko, B V 2021, ' Long-term effects of a modified, low-protein infant formula on growth and body composition: Follow-up of a randomized, double-blind, equivalence trial ', Clinical Nutrition, vol. 40, no. 6, pp. 3914-3921 . https://doi.org/10.1016/j.clnu.2021.04.034

Background & aim: High protein intake in early life is associated with an increased risk of childhood obesity. Feeding a modified lower-protein (mLP) infant formula (1.7 g protein/100 kcal) until the age of 6 months is safe and supports adequate grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a241b015f6fdab903afc61db4de41e
https://research.rug.nl/en/publications/d44f8757-9eb0-4e82-9e14-109bc7c4919a

Rapid and selective manipulation of milk fatty acid composition in mice through the maternal diet during lactation

Autor: Annemarie Oosting, Henkjan J. Verkade, Diane Kegler, Bert J. M. van de Heijning, Eline M. van der Beek

Publikováno v: Journal of Nutritional Science, Vol 4 (2015)

Dietary fatty acid (FA) composition in early postnatal life can modulate growth and development and later metabolic health. Investigating programming effects of early dietary FA manipulations in rodents may be stressful and complicated due to the nee

Externí odkaz: https://doaj.org/article/b20861295c334df7acae05de66203c65

Early-Life Metabolic and Hormonal Markers in Blood and Growth until Age 2 Years: Results from a Randomized Controlled Trial in Healthy Infants Fed a Modified Low-Protein Infant Formula

Autor: Bert J. M. van de Heijning, Berthold Koletzko, Jos W. R. Twisk, Manja Fleddermann, Dewi van Harskamp, Marieke Abrahamse-Berkeveld, Johannes B. van Goudoever, Martijn J J Finken, Eline M. van der Beek, Stefanie M.P. Kouwenhoven

Publikováno v: Nutrients, 13(4):1159. MDPI AG
Kouwenhoven, S M P, Fleddermann, M, Finken, M J J, Twisk, J W R, van der Beek, E M, Abrahamse-Berkeveld, M, van de Heijning, B J M, van Harskamp, D, van Goudoever, J B & Koletzko, B V 2021, ' Early-life metabolic and hormonal markers in blood and growth until age 2 years: Results from a randomized controlled trial in healthy infants fed a modified low-protein infant formula ', Nutrients, vol. 13, no. 4, 1159 . https://doi.org/10.3390/nu13041159
Nutrients, Vol 13, Iss 1159, p 1159 (2021)
Nutrients
Volume 13
Issue 4
Nutrients, 13(4):1159. Multidisciplinary Digital Publishing Institute (MDPI)

Background: High protein intake in early life is associated with an increased risk of childhood obesity. Dietary protein intake may be a key mechanistic modulator through alterations in endocrine and metabolic responses. Objective: We aimed to determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3f8310427aebcd1dfc175a057a0fc9
https://research.rug.nl/en/publications/22135425-db95-4076-95fe-a59a3d945654

Effects of an early life diet containing large phospholipid-coated lipid globules on hepatic lipid metabolism in mice

Autor: Onne A H O, Ronda, Bert J M, van de Heijning, Ingrid, Martini, Albert, Gerding, Justina C, Wolters, Ydwine T, van der Veen, Martijn, Koehorst, Angelika, Jurdzinski, Rick, Havinga, Eline M, van der Beek, Folkert, Kuipers, Henkjan J, Verkade

Publikováno v: Scientific reports. 10(1)

We recently reported that feeding mice in their early life a diet containing a lipid structure more similar to human milk (eIMF, Nuturis) results in lower body weights and fat mass gain upon high fat feeding in later life, compared to control (cIMF).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b0bb96de08e2befb546f49a151048abb
https://pubmed.ncbi.nlm.nih.gov/32999305