Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Bert F. M. Van Zutphen"'
Publikováno v:
Journal of Applied Animal Welfare Science. 8:279-283
The concept of refinement is an important issue in the field of laboratory animal science. Refinement-based research aims to improve animal welfare, to increase the reliability of experimental outcome, and to diminish variation. In search of refineme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ced82c9d68a74335d4e21c7b1e348d
https://doi.org/10.1207/s15327604jaws0804_4
https://doi.org/10.1207/s15327604jaws0804_4
Publikováno v:
Alternatives to Laboratory Animals. 32:1-4
One of the articles contained within European Council Directive 86/609/EEC states that “Persons who carry out experiments or take part in them, and persons who take care of animals used for experiments, including duties of a supervisory nature, sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3fc90cf3125b636e9ce9aa6bb516f7
https://doi.org/10.1177/026119290403202s02
https://doi.org/10.1177/026119290403202s02
Autor:
Klaas Kramer, R. Remie, Caroline van Heijningen, Vera Baumans, Hans-Peter Voss, Anne Mulder, Bert F. M. Van Zutphen, Heleen A. van de Weerd
Publikováno v:
Alternatives to Laboratory Animals. 32:177-181
To assess the effect of procedures on animal welfare, various physiological parameters, such as body weight, hormone levels in plasma and/or urine, heart rate (HR), blood pressure and body temperature (BT), can be used. When measuring physiological p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbe35e1ad96987c5a06436c755a6266
https://doi.org/10.1177/026119290403201s29
https://doi.org/10.1177/026119290403201s29
Publikováno v:
Alternatives to Laboratory Animals. 32:13-19
The Third World Congress (1999, Bologna) celebrated the fortieth anniversary of the publication of Russell & Burch's The Principles of Humane Experimental Technique. There was the general notion that the Three Rs offer a unifying concept that contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e396b74e6bada08f449c02bfc6b25e
https://doi.org/10.1177/026119290403201s06
https://doi.org/10.1177/026119290403201s06
Autor:
G. F. Gillissen, Michal Pravenec, Thomas Kreitler, Hein A. van Lith, Anita Bonne, Claudia Gosele, Vladimir Kren, Maria den Bieman, Bert F. M. Van Zutphen
Publikováno v:
Molecular Biology Reports. 30:173-176
The fatty acid binding protein 6 gene (Fabp6) codes for ileal lipid binding protein. After sequencing of rat Fabp6, the gene was localized in a radiation hybrid (RH) map on chromosome 10. An intronless Fabp6 segment was found in four related rat inbr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::439eba067265427619c6f4bf1aae0b30
https://doi.org/10.1023/a:1024968606162
https://doi.org/10.1023/a:1024968606162
Autor:
Æ Lankhorst, Bert F. M. Van Zutphen, Ingeborg D de Wolf, X.M. Fielmich-Bouman, Hein A. van Lith, Vladimír Křen, Anton C. Beynen, Michal Pravenec, Bernard A. van Oost
Publikováno v:
Journal of Trace Elements in Medicine and Biology. 17:177-182
The question addressed is whether cholesterol intake reduces the hepatic copper content in rats. For this purpose we have compared the hepatic copper content of two selected rat inbred strains after feeding the animals a control or a high fat, high c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9675044bc7c55541e2b3f15bcc42b022
https://doi.org/10.1016/s0946-672x(03)80023-8
https://doi.org/10.1016/s0946-672x(03)80023-8
Autor:
Vaclav Zidek, V. Bila, Hein A. van Lith, Bert F. M. Van Zutphen, Vlastimil Kostka, Michal Pravenec, Anita Bonne, Alena Musilova, Drahomira Krenova, Maria den Bieman, Vladimir Kren, G. F. Gillissen
Publikováno v:
Biochemical Genetics. 41:77-89
The amplified fragment length polymorphism (AFLP) technique has been used to enhance marker density in a large set of recombinant inbred strains (H x B and B x H) derived from a spontaneously hypertensive rat (SHR/OlaIpcv) and a Brown-Norway (BN.lx/C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::974dc31c36fe87f86d7d8388851799c2
https://doi.org/10.1023/a:1022069816135
https://doi.org/10.1023/a:1022069816135
Publikováno v:
Journal of Applied Animal Welfare Science. 4:91-103
In the laboratory, individual housing of male mice who otherwise show aggression is common practice. Because mice are a social species, the question arises whether this procedure is right from the animals' point of view. This study tested the prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bb560d0043c287d092d6ada503220b5
https://doi.org/10.1207/s15327604jaws0402_1
https://doi.org/10.1207/s15327604jaws0402_1
Publikováno v:
Physiology and Behavior, 72(5), 675-683. PERGAMON-ELSEVIER SCIENCE LTD
Aggression in group-housed male mice is known to be influenced by both cage size and group size. However, the interdependency of these two parameters has not been studied yet. In this study, the level of aggression in groups of three, five, or eight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d8c450f90bdb56aba0157b40ccfa70
https://doi.org/10.1016/s0031-9384(01)00425-5
https://doi.org/10.1016/s0031-9384(01)00425-5
Autor:
Marie Jáchymová, Vladimir Kren, Hein A. van Lith, M Pravenec, Bert F. M. Van Zutphen, Drahomira Krenova, Milada Sladká, Blanka Míková, Yun-Fai Chris Lau, N. Qi, Vaclav Zidek, Anita Bonne, Elizabeth St. Lezin, Karel Horky
Publikováno v:
Hypertension. 37:1147-1152
Abstract —Previous studies with chromosome-Y consomic strains of spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats suggest that a quantitative trait locus for blood pressure regulation exists on chromosome Y. To test this hypothesis in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b98faf0e12ae0b62a8426962d83851b
https://doi.org/10.1161/01.hyp.37.4.1147
https://doi.org/10.1161/01.hyp.37.4.1147