C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line

Autor: Zoch, Ansgar, Konieczny, Gabriela, Auchynnikava, Tania, Stallmeyer, Birgit, Rotte, Nadja, Heep, Madeleine, Berrens, Rebecca V., Schito, Martina, Kabayama, Yuka, Schöpp, Theresa, Kliesch, Sabine, Houston, Brendan, Nagirnaja, Liina, O’Bryan, Moira K., Aston, Kenneth I., Conrad, Donald F., Rappsilber, Juri, Allshire, Robin C., Cook, Atlanta G., Tüttelmann, Frank, O’Carroll, Dónal

Publikováno v: In Molecular Cell 21 March 2024 84(6):1021-1035

Role of small RNAs and chromatin in transposable element silencing during global demethylation

Autor: Berrens, Rebecca V.

DNA methylation entails the addition of a methyl group to the 5-carbon of the cytosine base of the DNA. This modification is important during many biological processes such as imprinting, X-chromosome inactivation, cell differentiation as well as sil

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.744435

Two-factor authentication underpins the precision of the piRNA pathway.

Autor: Dias Mirandela, Madeleine, Zoch, Ansgar, Leismann, Jessica, Webb, Shaun, Berrens, Rebecca V., Valsakumar, Devisree, Kabayama, Yuka, Auchynnikava, Tania, Schito, Martina, Chowdhury, Tamoghna, MacLeod, David, Xiang, Xinyu, Zou, Juan, Rappsilber, Juri, Allshire, Robin C., Voigt, Philipp, Cook, Atlanta G., Barau, Joan, O’Carroll, Dónal

Publikováno v: Nature; Oct2024, Vol. 634 Issue 8035, p979-985, 7p

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SPOCD1 is an essential executor of piRNA-directed 1 de novo DNA methylation

Autor: Zoch, Ansgar, Auchynnikava, Tania, Berrens, Rebecca V., Kabayama, Yuka, Schöpp, Theresa, Heep, Madeleine, Vasiliauskaitė, Lina, Pérez-Rico, Yuvia A, Cook, Atlanta G., Shkumatava, Alena, Rappsilber, Juri, Allshire, Robin C., O'Carroll, Donal

Publikováno v: Zoch, A, Auchynnikava, T, Berrens, R V, Kabayama, Y, Schöpp, T, Heep, M, Vasiliauskaitė, L, Pérez-Rico, Y A, Cook, A G, Shkumatava, A, Rappsilber, J, Allshire, R C & O'Carroll, D 2020, ' SPOCD1 is an essential executor of piRNA-directed 1 de novo DNA methylation ', Nature, vol. 584, no. 7822, pp. 635-639 . https://doi.org/10.1038/s41586-020-2557-5

In mammals, the acquisition of the germline from the soma provides the germline with an essential challenge, the necessity to erase and reset genomic methylation. In the malegermline RNA-directed DNA methylation silences young active transposable ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::add534c246aa6c66e423784761f1e911
https://hdl.handle.net/20.500.11820/4b4c7b36-91df-431f-8781-ec561331adc9