Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Bernt Hjertner"'
Autor:
Stina Hellman, Frida Martin, Eva Tydén, Mikael E. Sellin, Albin Norman, Bernt Hjertner, Pia Svedberg, Caroline Fossum
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-15 (2024)
Abstract Stem cell-derived organoid cultures have emerged as attractive experimental models for infection biology research regarding various types of gastro-intestinal pathogens and host species. However, the large size of infectious nematode larvae
Externí odkaz:
https://doaj.org/article/53640d19141e48ddb8fb6e9eb7bd6b39
Autor:
Bernt Hjertner, Claudia Lützelschwab, Elise Schieck, Benjamin Nzau, Sonal Henson, Marie Sjölund, Caroline Fossum, Ulf Magnusson
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256106 (2021)
Indiscriminate use of antibiotics to treat infections that are of viral origin contributes to unnecessary use which potentially may induce resistance in commensal bacteria. To counteract this a number of host gene transcriptional studies have been co
Externí odkaz:
https://doaj.org/article/eb21e05bd30b446e9646f9e0a73431ad
Publikováno v:
Veterinary Research, Vol 49, Iss 1, Pp 1-11 (2018)
Abstract The immunomodulatory effect of a new particulate adjuvant, G3, alone or in combination with agonists to TLR2/1 or TLR5 was evaluated in cultures of equine PBMC. Exposure to the G3 adjuvant up-regulated genes encoding IFN-γ, IL-1β, IL-6, IL
Externí odkaz:
https://doaj.org/article/7e15da9574b742b092f5b246b02a04e4
Autor:
Viktor Ahlberg, Bernt Hjertner, Per Wallgren, Stina Hellman, Karin Lövgren Bengtsson, Caroline Fossum
Publikováno v:
Veterinary Research, Vol 48, Iss 1, Pp 1-14 (2017)
Abstract Saponin-based adjuvants have been widely used to enhance humoral and cellular immune responses in many species, but their mode of action is not fully understood. A characterization of the porcine transcriptional response to Matrix-M was perf
Externí odkaz:
https://doaj.org/article/664cbe99510b4794b2d847c969fe8989
Autor:
Elise Schieck, Sonal P. Henson, Benjamin M. Nzau, Caroline Fossum, Claudia María Lützelschwab, Ulf Magnusson, Marie Sjölund, Bernt Hjertner
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 9, p e0256106 (2021)
PLoS ONE, Vol 16, Iss 9, p e0256106 (2021)
Indiscriminate use of antibiotics to treat infections that are of viral origin contributes to unnecessary use which potentially may induce resistance in commensal bacteria. To counteract this a number of host gene transcriptional studies have been co
Autor:
Eva Tydén, Stina Hellman, Bernt Hjertner, Bror Morein, Caroline Fossum, Kefei Hu, Frida Nilsfors
Publikováno v:
Parasite Immunology
Aims To generate different larval stages of Strongylus vulgaris and to study cytokine responses in cultures of eqPBMC exposed to defined larval stages of S. vulgaris and cyathostomins with the aim to understand the early immune reaction to these para
Publikováno v:
The Veterinary Journal. 206:97-104
Inflammatory bowel disease (IBD) in horses is an idiopathic disorder, encompassing different types of chronic intestinal inflammation. The pathogenesis of the disease remains to be established, but it has been suggested that an imbalance between regu
Publikováno v:
Vaccine. 36(23)
A preferred adjuvant should promote both Th1 and Th2 responses. However, most adjuvants in common use are biased towards a Th2-driven response. Therefore, the ability of a novel saponin-based adjuvant G3 to inducing balanced Th1 and Th2 responses in
Autor:
Karin Lövgren Bengtsson, Navisraj Balagunaseelan, Lisbeth Fuxler, Wasin Charerntantanakul, Bernt Hjertner, Viktor Ahlberg, Kathy Mcintosh, Caroline Fossum, Per Wallgren
Publikováno v:
Veterinary Immunology and Immunopathology. 158:53-61
The early inflammatory response to Matrix-M was evaluated in pigs. Adverse reactions measured as body temperature, appetite, activity level and reaction at the site of injection were not observed after s.c. injection with three doses of the adjuvant
Publikováno v:
The Veterinary Journal. 197:817-823
There is accumulating evidence for the involvement of pro-inflammatory cytokines associated with a T helper 17 response in intestinal disorders such as inflammatory bowel disease (IBD) in humans. The involvement of interleukin (IL)-17 or IL-23 in equ