Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bernice Woon Li Lee"'
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/e0617b1d20174c67b17340e2ad076255
Autor:
Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-13 (2024)
Abstract Epitranscriptomic RNA modifications are crucial for the maintenance of glioma stem cells (GSCs), the most malignant cells in glioblastoma (GBM). 3-methylcytosine (m3C) is a new epitranscriptomic mark on RNAs and METTL8 represents an m3C writ
Externí odkaz:
https://doaj.org/article/1d37dfa6251d462ab7c00e54f1198368
Publikováno v:
Redox Biology, Vol 25, Iss , Pp - (2019)
The failure in effective cancer treatment is thought to be attributed to a subpopulation of tumor cells with stem cell-like properties. These cancer stem cells (CSCs) are intimately linked to tumor initiation, heterogeneity, maintenance, recurrence a
Externí odkaz:
https://doaj.org/article/50a794fde6d7431d833e40e81bedc458
Autor:
Jeehyun Yoon, Oleg V. Grinchuk, Roberto Tirado-Magallanes, Zhen Kai Ngian, Emmy Xue Yun Tay, You Heng Chuah, Bernice Woon Li Lee, Jia Feng, Karen Carmelina Crasta, Chin Tong Ong, Touati Benoukraf, Derrick Sek Tong Ong
Publikováno v:
Cell Death & Differentiation. 29:1379-1394
The histone variant H2AZ is overexpressed in diverse cancer types where it facilitates the accessibility of transcriptional regulators to the promoters of cell cycle genes. However, the molecular basis for its dysregulation in cancer remains unknown.
Autor:
Tan Boon Toh, Jin Hui Hor, Roberto Tirado Magallanes, Xiaogang Liu, Oleg V. Grinchuk, Jianhong Ching, Shi-Yan Ng, Chandra S. Verma, Ming Joo Koh, Jeehyun Yoon, Jean-Paul Kovalik, Zhenglin Li, Jhin Jieh Lim, Edward Kai-Hua Chow, You Heng Chuah, Emmy Xue Yun Tay, Chen-Fei Liu, Touati Benoukraf, Melgious Jin Yan Ang, Derrick Sek Tong Ong, Srinivasaraghavan Kannan, Kimberly Chia, Haonan Zhao, Bernice Woon Li Lee, Ker Zhing Lok
Glioblastoma (GBM) is a uniformly lethal disease driven by glioma stem cells (GSCs). Here, we use a chemical biology approach to unveil previously unknown GBM dependencies. By studying sulconazole (SN) with anti-GSC properties, we find that SN disrup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d92600c8c4e652570ebb19708d2d14
https://hdl.handle.net/10356/154365
https://hdl.handle.net/10356/154365