Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bernhard Wilke"'
Autor:
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel, Bernhard Wilke, Stephan Awe, Andrea Nist, Thorsten Stiewe, Oliver Stehling, Sven-Andreas Freibert, Till Adhikary, Ho-Ryun Chung
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
It has remained yet unclear which soluble factors regulate the anti-inflammatory macrophage phenotype observed in both homeostasis and tumourigenesis. We show here that haptoglobin, a major serum protein with elusive immunoregulatory properties, bind
Externí odkaz:
https://doaj.org/article/507e4731fed9448d9eeb658de17cc758
Autor:
Laura Zein, Josina Grossmann, Helena Swoboda, Christina Borgel, Bernhard Wilke, Stephan Awe, Andrea Nist, Thorsten Stiewe, Oliver Stehling, Sven-Andreas Freibert, Till Adhikary, Ho-Ryun Chung
Haptoglobin is the major detoxifier of hemoglobin. Moreover, haptoglobin modulates the inflammatory responseviaNFκB. In some studies haptoglobin represses and in others it activates NFκB. We show here that these conflicting results are explainable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69dc39b05cc522ee670ea227f6a8cd4e
https://doi.org/10.1101/2022.11.22.516855
https://doi.org/10.1101/2022.11.22.516855
Autor:
Nathalie Legrand, Wibke E. Diederich, Clemens L. Bretscher, Svenja Zielke, Michael Daude, Till Adhikary, Barbara Fritz, Bernhard Wilke
Publikováno v:
Nucleic Acids Research
In the absence of ligands, the nuclear receptor PPARβ/δ recruits the NCOR and SMRT corepressors, which form complexes with HDAC3, to canonical target genes. Agonistic ligands cause dissociation of corepressors and enable enhanced transcription. Vic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2f6b45211467065d2f4f53873a764e
https://pubmed.ncbi.nlm.nih.gov/31428774
https://pubmed.ncbi.nlm.nih.gov/31428774
Autor:
Nathalie Legrand, Barbara Fritz, Clemens L. Bretscher, Svenja Zielke, Michael Daude, Bernhard Wilke, Till Adhikary, Wibke E. Diederich
Repression of transcription by nuclear receptors involves NCOR and SMRT corepressor complexes, which harbour the deacetylase HDAC3 as a subunit. Both deacetylase-dependent and -independent repression mechanisms have been reported for these complexes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af1ffe1b84e0dc67e8ca21c5eed9b2a
Autor:
Sabine Müller-Brüsselbach, Kerstin Kaddatz, Markus Rieck, Rolf Müller, Jürgen Adamkiewicz, Bernhard Wilke
Publikováno v:
Proteomics. 7(8)
The peroxisome proliferator activated receptor-beta (PPARbeta) plays an essential role in lipid metabolism, immune modulation, differentiation and cell proliferation. There is also strong evidence for a function in oncogenesis and tumor vascularizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3768b372aa42ab3b603f92edf1915507
https://pubmed.ncbi.nlm.nih.gov/17380536
https://pubmed.ncbi.nlm.nih.gov/17380536