Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bernhard Sissolak"'
Autor:
Gabriele Recanati, Magdalena Pappenreiter, Christoph Gstoettner, Patrick Scheidl, Elena Domínguez Vega, Bernhard Sissolak, Alois Jungbauer
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 10, Pp n/a-n/a (2023)
Abstract Continuous precipitation coupled with continuous tangential flow filtration is a cost‐effective alternative for the capture of recombinant antibodies from crude cell culture supernatant. The removal of surge tanks between unit operations,
Externí odkaz:
https://doaj.org/article/eea721d339984f26a23f3ab7209c98dd
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Reliable process development is accompanied by intense experimental effort. The utilization of an intensified design of experiments (iDoE) (intra-experimental critical process parameter (CPP) shifts combined) with hybrid modeling potentially reduces
Externí odkaz:
https://doaj.org/article/815c05c62f06407ab14f2190e32c1bfb
Autor:
Gabriele Recanati, Rowena Coca-Whiteford, Patrick Scheidl, Bernhard Sissolak, Alois Jungbauer
Publikováno v:
Process Biochemistry. 118:145-153
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
In aerobic cell cultivation processes, dissolved oxygen is a key process parameter, and an optimal oxygen supply has to be ensured for proper process performance. To achieve optimal growth and/or product formation, the rate of oxygen transfer has to
Externí odkaz:
https://doaj.org/article/6d2365fb73db4d6aac62887b29a8e13f
Autor:
Magdalena Pappenreiter, Hubert Schwarz, Bernhard Sissolak, Alois Jungbauer, Véronique Chotteau
Publikováno v:
Journal of Chemical Technology & Biotechnology.
Autor:
Magdalena Pappenreiter, Benjamin Bayer, Marijan Logarušić, Bernhard Sissolak, Alois Jungbauer
Publikováno v:
Biochemical Engineering Journal. 193:108876
Autor:
Magdalena Pappenreiter, Sebastian Döbele, Gerald Striedner, Alois Jungbauer, Bernhard Sissolak
Publikováno v:
Bioprocess and biosystems engineering. 45(9)
Perfusion bioreactors are commonly used for the continuous production of monoclonal antibodies (mAb). One potential benefit of continuous bioprocessing is the ability to operate under steady-state conditions for an extended process time. However, the
Publikováno v:
Biotechnology progressREFERENCES. 38(5)
Glycation on lysine side chains of recombinant monoclonal antibodies (mAb) is a well-known phenomenon in manufacturing processes of biopharmaceuticals that potentially alter the efficacy of the therapeutic protein. In the present study, we report kin
Glycation on lysine side chains of recombinant monoclonal antibodies (mAb) is a well known phenomenon in manufacturing processes of biopharmaceuticals that potentially alter the efficacy of the therapeutic protein. Previously, we reported a method to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dd1b29af97feba666a2a59263435ff8
https://doi.org/10.22541/au.163506359.97922307/v1
https://doi.org/10.22541/au.163506359.97922307/v1