Výsledky vyhledávání - "Bernhard Schoenenberger"

Akademický článek

Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus

Autor: Sabine Krevet, Lu Shen, Timon Bohnen, Bernhard Schoenenberger, Roland Meier, Markus Obkircher, Klara Bangert, Rudolf Koehling, Eric Allenspach, Roland Wohlgemuth, Bettina Siebers, Christopher Bräsen

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

The availability of metabolic intermediates is a prerequisite in many fields ranging from basic research, to biotechnological and biomedical applications as well as diagnostics. 2-keto-3-deoxy-6-phosphogluconate (KDPG) is the key intermediate of the

Externí odkaz: https://doaj.org/article/9bd3b031054247f28cf5a6357485a248

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Efficient biocatalytic synthesis of D-tagatose 1,6-diphosphate by LacC-catalysed phosphorylation of D-tagatose 6-phosphate

Autor: Roland Wohlgemuth, Stefanie Kind, Bernhard Schoenenberger, Thorsten Eggert, Markus Obkircher, Roland Meier

Publikováno v: Biocatalysis and Biotransformation. 38:53-63

D-tagatose 1,6-diphosphate is an important metabolite which can be formed via the classical tagatose 6-phosphate pathway or via the tagatose 1-phosphate pathway discovered more recently. Th...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4b60c80defc52793fde18914cb79ef7
https://doi.org/10.1080/10242422.2019.1634694

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Biocatalytic asymmetric Michael addition reaction ofl-arginine to fumarate for the green synthesis of N-(([(4S)-4-amino-4-carboxy-butyl]amino)iminomethyl)-l-aspartic acid lithium salt (l-argininosuccinic acid lithium salt)

Autor: Roland Wohlgemuth, Roland Meier, H. Brundiek, Agata Wszolek, Bernhard Schoenenberger, Markus Obkircher

Publikováno v: RSC Adv.. 7:48952-48957

The basic natural amino acid L-argininosuccinate containing two chiral centers occurs in L-alanine, L-arginine, L-aspartate, L-glutamate and L-proline metabolic pathways and plays a role in the biosynthesis of secondary metabolites and other amino ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2da2b32e10420d9b13aeae175588c7a8
https://doi.org/10.1039/c7ra10236d

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Facile synthesis of D-xylulose-5-phosphate and L-xylulose-5-phosphate by xylulokinase-catalyzed phosphorylation

Autor: Bernhard Schoenenberger, Stefanie Kind, Markus Obkircher, Roland Wohlgemuth, Thorsten Eggert, Norman Hardt

The enantiomeric metabolites D-xylulose-5-phosphate and L-xylulose-5-phosphate are highly relevant in numerous important pathways from microbial to human metabolism. As these phosphorylated chiral metabolites are required for the analysis of enzyme a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71dbb2345636557d40f0bc80eceb9baf

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Recombinant AroL-Catalyzed Phosphorylation for the Efficient Synthesis of Shikimic Acid 3-Phosphate

Autor: Agata Wszolek, Henrike Brundiek, Roland Wohlgemuth, Markus Obkircher, Bernhard Schoenenberger, Roland Meier

Publikováno v: Biotechnology journal. 13(8)

Shikimic acid 3-phosphate, as a central metabolite of the shikimate pathway, is of high interest as enzyme substrate for 5-enolpyruvoyl-shikimate 3-phosphate synthase, a drug target in infectious diseases and a prime enzyme target for the herbicide g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4b0ea5fa224e05b789efac13696793
https://pubmed.ncbi.nlm.nih.gov/29697210

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Biocatalytic Asymmetric Phosphorylation Catalyzed by Recombinant Glycerate-2-Kinase

Autor: Markus Obkircher, Bernhard Schoenenberger, Birhanu M. Kinfu, Norman Hardt, Wolfgang R. Streit, Roland Wohlgemuth, Jennifer Chow

Publikováno v: Chembiochem : a European journal of chemical biology. 18(15)

The efficient synthesis of pure d-glycerate-2-phosphate is of great interest due to its importance as an enzyme substrate and metabolite. Therefore, we investigated a straightforward one-step biocatalytic phosphorylation of glyceric acid. Glycerate-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d159fd51f18bb96bb449fb5dad6d88
https://pubmed.ncbi.nlm.nih.gov/28421660

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Chemical and enzymatic methodologies for the synthesis of enantiomerically pure glyceraldehyde 3-phosphates

Autor: Bernhard Schoenenberger, Roland Wohlgemuth, Dominik Gauss

Publikováno v: Carbohydrate Research. 389:18-24

Glyceraldehyde 3-phosphates are important intermediates of many central metabolic pathways in a large number of living organisms. d-Glyceraldehyde 3-phosphate (d-GAP) is a key intermediate during glycolysis and can as well be found in a variety of ot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e344b53e84e4ca290b0c1a670e6265
https://doi.org/10.1016/j.carres.2013.12.023

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Biocatalytic asymmetric phosphorylation of mevalonate

Autor: Bernhard Schoenenberger, Rie Matsumi, J. van der Oost, Thomas Milesi, C. Hellriegel, Roland Wohlgemuth

Publikováno v: RSC Advances : An international journal to further the chemical sciences, 4(25), 12989-12994
RSC Advances : An international journal to further the chemical sciences 4 (2014) 25

The excellent selectivity of the mevalonate kinase-catalyzed phosphorylation of mevalonate simplifies lengthy multi-step routes to (R)-mevalonate-5-phosphate to a one-step biocatalytic reaction, because the phosphate group can be transferred directly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126de6d07dcab5697a1bb961f59d793c
https://doi.org/10.1039/c4ra01299b

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