Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Bernhard Rupp"'
Autor:
Laura Krismer, Helge Schöppe, Stefanie Rauch, David Bante, Bernhard Sprenger, Andreas Naschberger, Francesco Costacurta, Anna Fürst, Anna Sauerwein, Bernhard Rupp, Teresa Kaserer, Dorothee von Laer, Emmanuel Heilmann
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-20 (2024)
Abstract The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an epidemic, zoonotically emerging pathogen initially reported in Saudi Arabia in 2012. MERS-CoV has the potential to mutate or recombine with other coronaviruses, thus acquiring
Externí odkaz:
https://doaj.org/article/1322a7caaeab4ab2b156087e0d939fa6
Autor:
Jesse Hudspeth, Kai Rogge, Sebastian Dörner, Maximilian Müll, Dirk Hoffmeister, Bernhard Rupp, Sebastiaan Werten
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Psilocybin, the natural hallucinogen produced by Psilocybe (“magic”) mushrooms, holds great promise for the treatment of depression and several other mental health conditions. The final step in the psilocybin biosynthetic pathway, dimeth
Externí odkaz:
https://doaj.org/article/92466dacb5884849b963b2cbf8c9de09
Autor:
Emmanuel Heilmann, Francesco Costacurta, Stephan Geley, Seyad Arad Mogadashi, Andre Volland, Bernhard Rupp, Reuben Stewart Harris, Dorothee von Laer
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
A vesicular stomatitis virus (VSV)-based assay enables high-throughput screening for small molecular protease inhibitors that can block viral proteases, like the Mpro/3CLpro/Nsp5 in SARS-CoV-2.
Externí odkaz:
https://doaj.org/article/ca9da23218ea4e68b17aa315026f2d0f
Autor:
Marek Grabowski, Joanna M. Macnar, Marcin Cymborowski, David R. Cooper, Ivan G. Shabalin, Miroslaw Gilski, Dariusz Brzezinski, Marcin Kowiel, Zbigniew Dauter, Bernhard Rupp, Alexander Wlodawer, Mariusz Jaskolski, Wladek Minor
Publikováno v:
IUCrJ, Vol 8, Iss 3, Pp 395-407 (2021)
As part of the global mobilization to combat the present pandemic, almost 100 000 COVID-19-related papers have been published and nearly a thousand models of macromolecules encoded by SARS-CoV-2 have been deposited in the Protein Data Bank within les
Externí odkaz:
https://doaj.org/article/e19ec1f7d95c4318919a6c73913467c7
Autor:
Mariusz Jaskolski, Zbigniew Dauter, Ivan G. Shabalin, Miroslaw Gilski, Dariusz Brzezinski, Marcin Kowiel, Bernhard Rupp, Alexander Wlodawer
Publikováno v:
IUCrJ, Vol 8, Iss 2, Pp 238-256 (2021)
The appearance at the end of 2019 of the new SARS-CoV-2 coronavirus led to an unprecedented response by the structural biology community, resulting in the rapid determination of many hundreds of structures of proteins encoded by the virus. As part of
Externí odkaz:
https://doaj.org/article/47485dd18ab647e7b2029b71252f82f0
Autor:
Bernd Schöpf, Hansi Weissensteiner, Georg Schäfer, Federica Fazzini, Pornpimol Charoentong, Andreas Naschberger, Bernhard Rupp, Liane Fendt, Valesca Bukur, Irina Giese, Patrick Sorn, Ana Carolina Sant’Anna-Silva, Javier Iglesias-Gonzalez, Ugur Sahin, Florian Kronenberg, Erich Gnaiger, Helmut Klocker
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The re-wiring of the metabolic machinery is a common feature in cancer. Here, the authors show, using paired normal and prostate cancer samples that the cancer samples exhibit a shift to succinate respiration, which is associated with elevated levels
Externí odkaz:
https://doaj.org/article/5f0501c636064d6cb8123ea16319c072
Autor:
Marcus Borrmann, Sonja Lindner, Kathrin Hofer-Fischanger, Robert Rehb, Katrin Pechstädt, Roswitha Wiedenhofer, Gabriele Schwarze, Eva-Maria Adamer-König, Robert Mischak, Karl P. Pfeiffer, Johann Harer, Katharina Weinzerl, Christian Hartmann, Bernhard Rupp, Regina E. Roller-Wirnsberger
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
In 2013, the European Commission founded the platform European Innovation Partnership on Active and Healthy Aging as a communication and innovation network in this domain. The goal of the current study was the development of an integrated regional ec
Externí odkaz:
https://doaj.org/article/4731330edf084d319b057f35abb89487
Publikováno v:
IUCrJ, Vol 1, Iss 3, Pp 179-193 (2014)
Whereas the vast majority of the more than 85 000 crystal structures of macromolecules currently deposited in the Protein Data Bank are of high quality, some suffer from a variety of imperfections. Although this fact has been pointed out in the past,
Externí odkaz:
https://doaj.org/article/cb74cb9d414941098e8ef5d8ea6bef35
Autor:
Can Gollmann-Tepeköylü, Michael Graber, Jakob Hirsch, Sophia Mair, Andreas Naschberger, Leo Pölzl, Felix Nägele, Elke Kirchmair, Gerald Degenhart, Egon Demetz, Richard Hilbe, Hao-Yu Chen, James C. Engert, Anna Böhm, Nadja Franz, Daniela Lobenwein, Daniela Lener, Christiane Fuchs, Anna Weihs, Sonja Töchterle, Georg F. Vogel, Victor Schweiger, Jonas Eder, Peter Pietschmann, Markus Seifert, Florian Kronenberg, Stefan Coassin, Michael Blumer, Hubert Hackl, Dirk Meyer, Gudrun Feuchtner, Rudolf Kirchmair, Jakob Troppmair, Markus Krane, Günther Weiss, Sotirios Tsimikas, George Thanassoulis, Michael Grimm, Bernhard Rupp, Lukas A. Huber, Shen-Ying Zhang, Jean-Laurent Casanova, Ivan Tancevski, Johannes Holfeld
Publikováno v:
Circulation. 147:1518-1533
Background: Calcific aortic valve disease (CAVD) is characterized by a phenotypic switch of valvular interstitial cells to bone-forming cells. Toll-like receptors (TLRs) are evolutionarily conserved pattern recognition receptors at the interface betw
Publikováno v:
memo - Magazine of European Medical Oncology. 16:79-90
SummaryChimeric antigen receptor (CAR) T cell therapies offer a promising new therapeutic option for treating B cell malignancies, for instance relapsed or refractory diffuse large B cell lymphoma (DLBCL). However, patient access to this type of cell