Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bernhard Pilz"'
Autor:
Damian Counsell, Dieter O. Fürst, Bernhard Pilz, Eberhard von Hodenberg, Karl Josef Osterziel, Andreas Perrot, Cemil Özcelik, Arnold Vornwald, Priska Binner, Rainer Dietz, Yvonne Martiniak, Peter F.M. van der Ven, Katrin Hoffmann, Christian Geier, Katja Gehmlich, Thomas Scheffold, Peter Nürnberg
Background— Muscle LIM protein (MLP) is an essential nuclear regulator of myogenic differentiation. Additionally, it may act as an integrator of protein assembly of the actin-based cytoskeleton. MLP-knockout mice develop a marked cardiac hypertroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099ffd6c85a6e829273fe713cba0c6aa
https://doi.org/10.1161/01.cir.0000056522.82563.5f
https://doi.org/10.1161/01.cir.0000056522.82563.5f
Autor:
Martin W. Bergmann, F. von Knobelsdorff-Brenkenhoff, T. Polch, C.M. Gross, Bernhard Pilz, Steffen Bohl, J. Schulz-Menger
Publikováno v:
Der Kardiologe. 1:190-196
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6220e2e6683c2d7fd8e2b0b48376575
https://doi.org/10.1007/s12181-007-0014-4
https://doi.org/10.1007/s12181-007-0014-4
Autor:
David Louis Feldman, Wolfgang Derer, Silke Meiners, Bernhard Pilz, Ralf Dechend, Anette Fiebeler, Erdenechimeg Shagdarsuren, Petra Gratze, Dominik N. Müller, Randy L. Webb
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System, Vol 8 (2007)
We studied the effects of extremely low-dose human renin inhibition (aliskiren) with low angiotensin II receptor blockade (losartan) in a novel double-transgenic rat model harbouring both human renin and angiotensinogen genes. We found that low-dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::547c3ba9ba1b6d81c0f1ad8915051b01
https://doi.org/10.3317/jraas.2007.008
https://doi.org/10.3317/jraas.2007.008
Autor:
Volkmar Günzler, Carola Schubert, Vera Regitz-Zagrosek, Lars Roman Herda, Jens Fielitz, Evelyn Schuch, Sebastian Philipp, Bernhard Pilz, Roland Willenbrock
Publikováno v:
European Journal of Heart Failure. 9:336-342
Background: Pressure overload leads to myocardial remodelling with collagen accumulation, left ventricular hypertrophy (LVH), neurohormonal activation and myocardial dysfunction. Prolyl 4-hydroxylases (P4H) are involved in collagen maturation. Inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1e35b7b55fef946e92499cc81085de
https://doi.org/10.1016/j.ejheart.2006.10.006
https://doi.org/10.1016/j.ejheart.2006.10.006
Autor:
Michael Bader, Vera Saul, João Bosco Pesquero, Vanessa F. Merino, Volkmar Gross, Guixuan Chai, Cécile Cayla, Ovidiu Baltatu, Radu Iliescu, Mihail Todiras, Bernhard Pilz
Publikováno v:
The FASEB Journal. 21:1689-1698
Kinins play a central role in the modulation of cardiovascular function and in the pathophysiology of inflammation. These peptides mediate their effects by binding to two specific G-protein coupled receptors named B1 and B2. To evaluate the full func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b206031f2c1b3b3e0f0b3b5015b3aeb
https://doi.org/10.1096/fj.06-7175com
https://doi.org/10.1096/fj.06-7175com
Autor:
Rainer Dietz, Hassan Abdel-Aty, Jeanette Schulz-Menger, Ralf Wassmuth, Andreas Busjahn, Bernhard Pilz, Matthias G. Friedrich
Publikováno v:
Journal of Cardiovascular Magnetic Resonance. 8:741-746
The relation to the pressure gradient as assessed by echocardiography and the CMR-derived planimetry of the LVOT is not known, no values for the differentiation of obstruction exist. We studied 37 patients with hypertrophic cardiomyopathy and 14 heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4a9e231bb54f46c0aac20ac6239e83
https://doi.org/10.1080/10976640600737383
https://doi.org/10.1080/10976640600737383
Autor:
Wanja M. Bernhardt, Astrid Schiche, Sebastian Philipp, Rainer Dietz, Kai-Uwe Eckardt, Bernhard Pilz, Jens Fielitz, Vera Regitz-Zagrosek, Roland Willenbrock, Alexander Weidemann, Jan Steffen Jürgensen
Publikováno v:
European Journal of Heart Failure. 8:347-354
Prolyl hydroxylase domain-containing enzymes (PHD) hydroxylate a proline residue that controls the degradation of hypoxia induciblefactor (HIF). Hypoxia inhibits this hydroxylation thus increasing HIF levels. HIF is upregulated in ischemic tissues, g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f7f9011e547b88bd450e1a7b0ed71b
https://doi.org/10.1016/j.ejheart.2005.10.009
https://doi.org/10.1016/j.ejheart.2005.10.009
Autor:
Friedrich C. Luft, Anette Fiebeler, Dominik N. Müller, Hermann Haller, Erdenechimeg Shagdarsuren, Bernhard Pilz, Istvan Mazak, Christiane Viedt, Ralf Dechend, Carsten Lindschau, Joon-Keun Park
Publikováno v:
Circulation. 109:2792-2800
Background— In a double-transgenic human renin and human angiotensinogen rat model, we found that mineralocorticoid receptor (MR) blockade ameliorated angiotensin II (Ang II)–induced renal and cardiac damage. How Ang II and aldosterone (Ald) migh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6508be43e9844cdd25ae3725d98bd07
https://doi.org/10.1161/01.cir.0000131860.80444.ab
https://doi.org/10.1161/01.cir.0000131860.80444.ab
Publikováno v:
Hypertension. 43:911-917
Congestive heart failure (CHF) is the inability of the heart to deliver a sufficient oxygen supply to meet the metabolic demands of the tissues at normal filling pressures, both at rest and during exercise. CHF may arise from reduced inotropy, volume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432dbf74030eaaf00322253131f88f84
https://doi.org/10.1161/01.hyp.0000126439.64838.b9
https://doi.org/10.1161/01.hyp.0000126439.64838.b9
Autor:
Stefan Britsch, Kenneth R. Chien, Norbert Hubner, Carmen Birchmeier, Alistair N. Garratt, Nina Wettschureck, Bernhard Pilz, Bettina Erdmann, Cemil Özcelik
Publikováno v:
Proceedings of the National Academy of Sciences. 99:8880-8885
The ErbB2 ( Her2 ) proto-oncogene encodes a receptor tyrosine kinase, which is frequently amplified and overexpressed in human tumors. ErbB2 provides the target for a novel and effective antibody-based therapy (Trastuzumab/Herceptin) used for the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc79d305cd8093171ccdf4f1d130d23f
https://doi.org/10.1073/pnas.122249299
https://doi.org/10.1073/pnas.122249299