Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bernhard M.K. Gmeiner"'
Autor:
Thomas Erker, Michael Hintersteininger, Bernhard M.K. Gmeiner, Hilde Laggner, Lilian Lohninger, Monika Praschberger, Lenka Tomasova
Publikováno v:
Biochimie. 112:187-195
The transcription factor HIF-1α regulates the adaptive response of cells to hypoxia and oxidative stress. In addition, an important regulatory role for HIF-1α in immune reactions and inflammation is suggested. The present study attempts to investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba55d33304fb6ebe6951b1515994e41
https://doi.org/10.1016/j.biochi.2015.03.009
https://doi.org/10.1016/j.biochi.2015.03.009
Autor:
Norbert Leitinger, Markus Exner, Stylianos Kapiotis, Christoph W. Kopp, Gregor Holzer, Oswald Wagner, Bernhard M.K. Gmeiner, Gerhard Krönke, Harald Esterbauer
Publikováno v:
Thrombosis Research. 120:71-79
Introduction Tissue factor (TF) plays a pivotal role in the generation of thrombin in atherothrombotic disease. The oxidized phospholipid 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC), an active compound of minimally oxidized low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1342598870497b6c7a1163ba8da662e
https://doi.org/10.1016/j.thromres.2006.07.007
https://doi.org/10.1016/j.thromres.2006.07.007
Autor:
Bernhard M.K. Gmeiner, Hilde Laggner
4-HNE (4-hydroxy-2-nonenal) is a highly reactive α,β-unsaturated aldehyde generated from oxidation of polyunsaturated fatty acids and has been suggested to play a role in the pathogenesis of several diseases. 4-HNE can bind to amino acids, proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b92d4e02acf696b0c776286d3ab913e
https://doi.org/10.1016/bs.mie.2014.11.018
https://doi.org/10.1016/bs.mie.2014.11.018
Publikováno v:
Biochimie. 88:473-483
Apolipoprotein E (apoE) has been genetically linked to late-onset Alzheimer's disease. From the three common alleles (epsilon2, epsilon3 and epsilon4), epsilon4 has been suggested to promote amyloid beta (Ass) plaque fibrillation, one hallmark of Alz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bfceec434997e83cab1f62a38e4da6
https://doi.org/10.1016/j.biochi.2005.10.007
https://doi.org/10.1016/j.biochi.2005.10.007
Autor:
Marcela Hermann, Stylianos Kapiotis, Beda Hartmann, Roland Hofbauer, Markus Exner, Bernhard M.K. Gmeiner
Publikováno v:
Free Radical Biology and Medicine. 37:146-155
There is evidence that LDL oxidation may render the lipoprotein atherogenic. The myeloperoxidase–hydrogen peroxide (MPO/H2O2) system of activated phagocytes may be involved in this process. Chloride is supposed to be the major substrate for MPO, ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30db78295e186601d118ebf91ea8fa20
https://doi.org/10.1016/j.freeradbiomed.2004.04.039
https://doi.org/10.1016/j.freeradbiomed.2004.04.039
Autor:
Bernhard M.K. Gmeiner, Hilde Laggner, Stylianos Kapiotis, Markus Exner, Leopold Jirovetz, Marcela Hermann, Marianne Hollaus, Sabine M. Schreier
Publikováno v:
Biochimie. 94(11)
N-carbamoylation is the non-enzymatic reaction of cyanate with amino groups. Due to urea-formed cyanate in uremic patients beside carbamoylated proteins also free amino acid carbamoylation has been detected, a modification which has been linked to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e32f0684fa4576d5ab63144c58c984
https://pubmed.ncbi.nlm.nih.gov/22776434
https://pubmed.ncbi.nlm.nih.gov/22776434
Autor:
Hans Goldenberg, Markus Exner, Stefan Kopp, Barbara Scheiber-Mojdehkar, Stylianos Kapiotis, Brigitte Sturm, Bernhard M.K. Gmeiner, Marcela Hermann, Peter Chiba
Publikováno v:
Free radical research. 39(11)
Al(3+) stimulates Fe(2+) induced lipid oxidation in liposomal and cellular systems. Low-density lipoprotein (LDL) oxidation may render the particle atherogenic. As elevated levels of Al(3+) and increased lipid oxidation of LDL are found in sera of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9bbd8a9309836d82db784ea8ba5e09
https://pubmed.ncbi.nlm.nih.gov/16298749
https://pubmed.ncbi.nlm.nih.gov/16298749
Publikováno v:
Free radical research. 39(11)
The oxidative modification of LDL may play an important role in the early events of atherogenesis. Thus the identification of antioxidative compounds may be of therapeutic and prophylactic importance regarding cardiovascular disease. Copper-chlorophy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02876bafa119e2e676b7618f67b2e3f
https://pubmed.ncbi.nlm.nih.gov/16298745
https://pubmed.ncbi.nlm.nih.gov/16298745
Autor:
Markus Exner, Leopold Jirovetz, Stylianos Kapiotis, Bernhard M.K. Gmeiner, Hildegard Laggner, Harald Esterbauer, Marcela Hermann
Publikováno v:
Biochimie. 88(7)
Hypochlorite (HOCl) attacks amino acid residues in LDL making the particle atherogenic. Tryptophan is prone to free radical reactions and modification by HOCl. We hypothesized, that free tryptophan may quench the HOCl attack therefore protecting LDL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77db3de2901692e3b9757ff9b1c9d6cb
https://pubmed.ncbi.nlm.nih.gov/16488068
https://pubmed.ncbi.nlm.nih.gov/16488068
Publikováno v:
Journal of the Neurological Sciences. 333:e71
FRDA is an autosomal recessive neurodegenerative disease characterized by multiple symptoms such as progressive spinocerebellar ataxia, sensory nerve affection,diabetesmellitus andlife-limitinghypertrophic cardiomyopathy. FRDA is caused by a GAA-trin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1935ed3c1c9e665ee3849328ed7e6303
https://doi.org/10.1016/j.jns.2013.07.524
https://doi.org/10.1016/j.jns.2013.07.524