Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Bernhard Kluger"'
Autor:
Eva Hitzenhammer, Christoph Büschl, Michael Sulyok, Rainer Schuhmacher, Bernhard Kluger, Elisabeth Wischnitzki, Monika Schmoll
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background Filamentous fungi have evolved to succeed in nature by efficient growth and degradation of substrates, but also due to the production of secondary metabolites including mycotoxins. For Trichoderma reesei, as a biotechnological wor
Externí odkaz:
https://doaj.org/article/58bd0e65fbdf4e7da504838111b771a7
Autor:
Maria Doppler, Christoph Bueschl, Bernhard Kluger, Andrea Koutnik, Marc Lemmens, Hermann Buerstmayr, Justyna Rechthaler, Rudolf Krska, Gerhard Adam, Rainer Schuhmacher
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Untargeted approaches and thus biological interpretation of metabolomics results are still hampered by the reliable assignment of the global metabolome as well as classification and (putative) identification of metabolites. In this work we present an
Externí odkaz:
https://doaj.org/article/81687e14204249b8b3dadc0823df7501
Autor:
Maria Doppler, Bernhard Kluger, Christoph Bueschl, Barbara Steiner, Hermann Buerstmayr, Marc Lemmens, Rudolf Krska, Gerhard Adam, Rainer Schuhmacher
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
The major Fusarium mycotoxin deoxynivalenol (DON) is a virulence factor in wheat and has also been shown to induce defense responses in host plant tissue. In this study, global and tracer labeling with 13C were combined to annotate the overall metabo
Externí odkaz:
https://doaj.org/article/a256879a7b91424ea9cc29865bd29ea2
Autor:
Bernhard Kluger, Christoph Bueschl, Marc Lemmens, Herbert Michlmayr, Alexandra Malachova, Andrea Koutnik, Imer Maloku, Franz Berthiller, Gerhard Adam, Rudolf Krska, Rainer Schuhmacher
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119656 (2015)
In this study, a total of nine different biotransformation products of the Fusarium mycotoxin deoxynivalenol (DON) formed in wheat during detoxification of the toxin are characterized by liquid chromatography-high resolution mass spectrometry (LC-HRM
Externí odkaz:
https://doaj.org/article/d436f5ef383d4fc1ba651b39ac82493d
Autor:
Silvio Uhlig, Ana Stanic, Ingerd S. Hofgaard, Bernhard Kluger, Rainer Schuhmacher, Christopher O. Miles
Publikováno v:
Toxins, Vol 8, Iss 11, p 329 (2016)
A glutathione (GSH) adduct of the mycotoxin 4-deoxynivalenol (DON), together with a range of related conjugates, has recently been tentatively identified by LC-MS of DON-treated wheat spikelets. In this study, we prepared samples of DON conjugated at
Externí odkaz:
https://doaj.org/article/30c0de61426a4d30882ca10d8147f01f
Autor:
Maria Doppler, Bernhard Kluger, Christoph Bueschl, Christina Schneider, Rudolf Krska, Sylvie Delcambre, Karsten Hiller, Marc Lemmens, Rainer Schuhmacher
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 7, p 1017 (2016)
The evaluation of extraction protocols for untargeted metabolomics approaches is still difficult. We have applied a novel stable isotope-assisted workflow for untargeted LC-HRMS-based plant metabolomics , which allows for the first time every detecte
Externí odkaz:
https://doaj.org/article/1ae974281ff04bb3b0af1b87b1f67799
Autor:
Eliana Garcia Cossio, Bettina Nowotny, Wiebke Afhueppe, Bernhard Kluger, Berthold Hocher, Mira Pavkovic
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Diabetic kidney disease (DKD) remains the most common cause of the end-stage renal disease (ESRD) worldwide. Kidney fibrosis predicts functional decline and ESRD in many, but not all patients [1]. Autotaxin (ATX) is the enzyme con
Autor:
Maria Doppler, Christoph Bueschl, Gerhard G. Thallinger, Jacqueline Meng-Reiterer, Bernhard Kluger, Nora Katharina Nicole Neumann, Valentina Maschietto, Rudolf Krska, Rainer Schuhmacher
Publikováno v:
Analytical Chemistry
Stable isotope labeling (SIL) techniques have the potential to enhance different aspects of liquid chromatography-high-resolution mass spectrometry (LC-HRMS)-based untargeted metabolomics methods including metabolite detection, annotation of unknown
Autor:
Markus Bacher, Bernhard Kluger, Joseph Strauss, Roland Hellinger, Christoph Zutz, Kathrin Rychli, Yi-Ming Chiang, Martin Wagner, Bettina Faehnrich
Publikováno v:
Microbiological Research. 197:1-8
Butyrate, a small fatty acid, has an important role in the colon of ruminants and mammalians including the inhibition of inflammation and the regulation of cell proliferation. There is also growing evidence that butyrate is influencing the histone st
Autor:
Eva Hitzenhammer, Christoph Büschl, Michael Sulyok, Rainer Schuhmacher, Bernhard Kluger, Elisabeth Wischnitzki, Monika Schmoll
Publikováno v:
BMC Genomics
BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
Background Filamentous fungi have evolved to succeed in nature by efficient growth and degradation of substrates, but also due to the production of secondary metabolites including mycotoxins. For Trichoderma reesei, as a biotechnological workhorse fo