Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Bernhard J Woermann"'
Autor:
Hanna Janke, Friederike Pastore, Daniela Schumacher, Tobias Herold, Karl-Peter Hopfner, Stephanie Schneider, Wolfgang E Berdel, Thomas Büchner, Bernhard J Woermann, Marion Subklewe, Stefan K Bohlander, Wolfgang Hiddemann, Karsten Spiekermann, Harald Polzer
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89560 (2014)
About 30% of patients with acute myeloid leukemia (AML) harbour mutations of the receptor tyrosine kinase FLT3, mostly internal tandem duplications (ITD) and point mutations of the second tyrosine kinase domain (TKD). It was the aim of this study to
Externí odkaz:
https://doaj.org/article/b13bc09d27824706bc8cd843182112d3
Autor:
Christian Rausch, Maja Rothenberg-Thurley, Annika Dufour, Stephanie Schneider, Hanna Gittinger, Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Wolfgang Hiddemann, Jan Braess, Michael von Bergwelt-Baildon, Karsten Spiekermann, Tobias Herold, Klaus H. Metzeler
Publikováno v:
HemaSphere, Vol 7, p e6798588 (2023)
Externí odkaz:
https://doaj.org/article/aeabb7fd70fe4eb989ddd720b4227443
Autor:
Christian Rausch, Maja Rothenberg-Thurley, Annika Dufour, Stephanie Schneider, Hanna Gittinger, Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Wolfgang Hiddemann, Jan Braess, Michael von Bergwelt-Baildon, Karsten Spiekermann, Tobias Herold, Klaus H. Metzeler
Publikováno v:
Leukemia.
The revised 2022 European LeukemiaNet (ELN) AML risk stratification system requires validation in large, homogeneously treated cohorts. We studied 1118 newly diagnosed AML patients (median age, 58 years; range, 18–86 years) who received cytarabine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f213b3e459c329124d7c19aac7d3c5
https://doi.org/10.1038/s41375-023-01884-2
https://doi.org/10.1038/s41375-023-01884-2
Autor:
Aarif M. N. Batcha, Tobias Herold, Stefan K. Bohlander, Dennis Görlich, Bianka Ksienzyk, Wolfgang E. Berdel, Jan Braess, Wolfgang Hiddemann, Alexander Graf, Ulrich Mansmann, Stephanie Schneider, Maria Cristina Sauerland, Bernhard J. Woermann, Karsten Spiekermann, Stefan Krebs, Hanna Janke, Nikola P. Konstandin, Vindi Jurinovic, Julia Philippou-Massier, Klaus H. Metzeler, Stefan Canzar, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Helmut Blum
Publikováno v:
Leukemia 34, 2621–2634 (2020)
Previous studies have demonstrated that splicing factor mutations are recurrent events in hematopoietic malignancies. Their clinical characteristics and aberrant splicing patterns have been explored in myelodysplasia, however, their functional conseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b31530b59e4faf05a198628ca8ad1a
https://doi.org/10.1038/s41375-020-0839-4
https://doi.org/10.1038/s41375-020-0839-4
Autor:
Maja Rothenberg-Thurley, Jan-Niklas Eckardt, Richard Noppeney, Philipp A. Greif, Christoph Schliemann, Wolfgang E. Berdel, Norbert Frickhofen, Claudia D. Baldus, Gerhard Ehninger, Mathias Hänel, Christian Thiede, Dennis Görlich, Cristina Sauerland, Ralph Naumann, Martin Kaufmann, Christoph Röllig, Uwe Platzbecker, Utz Krug, Ulrich Kaiser, Hubert Serve, Alwin Kraemer, Markus Schaich, Friedrich Stölzel, Bernhard J. Woermann, Carsten Müller-Tidow, Tobias Herold, Andreas Neubauer, Andreas Burchert, Klaus H. Metzeler, Johannes Schetelig, Stefan W. Krause, Jan Moritz Middeke, Katja Sockel, Karsten Spiekermann, Kerstin Schaefer-Eckart, Sebastian Stasik, Wolfgang Hiddemann, Jan Braess, Andreas Hochhaus, Hermann Einsele, Tim H. Brümmendorf, Malte von Bonin, Michael Kramer, Martin Bornhäuser, Björn Steffen, Desiree Kunadt
Mutations of the isocitrate dehydrogenase-1 (IDH1) and IDH2 genes are among the most frequent alterations in acute myeloid leukemia (AML) and can be found in ∼20% of patients at diagnosis. Among 4930 patients (median age, 56 years; interquartile ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc862fde571105d6043fbbd83e873215
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85126099057
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85126099057
Autor:
Philipp A. Greif, Nikola P. Konstandin, Klaus H. Metzeler, Tobias Herold, Zlatana Pasalic, Bianka Ksienzyk, Annika Dufour, Friederike Schneider, Stephanie Schneider, Purvi M. Kakadia, Jan Braess, Maria Cristina Sauerland, Wolfgang E. Berdel, Thomas Büchner, Bernhard J. Woermann, Wolfgang Hiddemann, Karsten Spiekermann, Stefan K. Bohlander
Publikováno v:
Haematologica, Vol 97, Iss 12 (2012)
Background The RUNX1 (AML1) gene is a frequent mutational target in myelodysplastic syndromes and acute myeloid leukemia. Previous studies suggested that RUNX1 mutations may have pathological and prognostic implications.Design and Methods We screened
Externí odkaz:
https://doaj.org/article/596e43be834a4c889afdc656b60a7c71
Autor:
Wolfgang Hiddemann, Christopher C. Oakes, Dennis Görlich, Aarif M. N. Batcha, Alice S. Mims, Shelley Orwick, Stephanie Schneider, Maria Cristina Sauerland, Christopher J. Walker, Karilyn Larkin, Richard Stone, Vindi Jurinovic, Maja Rothenberg-Thurley, Klaus H. Metzeler, Joseph O. Moore, William Blum, James S. Blachly, Andrew J. Carroll, Karsten Spiekermann, Bernhard J. Woermann, Utz Krug, John C. Byrd, Jessica Kohlschmidt, Jan Braess, Richard A. Larson, Deedra Nicolet, Robert J. Mayer, Wolfgang E. Berdel, Bayard L. Powell, Jonathan E. Kolitz, Ann-Kathrin Eisfeld, Monica Cusan, Krzysztof Mrózek, Tobias Herold
Publikováno v:
Blood. 138:685-685
Background: AML is a disease affecting predominantly older patients (pts), but does occur across the entire age spectrum; younger adults [age Methods: We analyzed the molecular profiles of 2,823 adult AML pts enrolled onto clinical frontline protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e45d5fbc4794889c392ad4aa1d0a682
https://doi.org/10.1182/blood-2021-153015
https://doi.org/10.1182/blood-2021-153015
Autor:
Cora Husemann, Markus Möbs, Timothy Looney, Michael Hummel, Christopher Allen, Bernhard J. Woermann, Karsten Kleo
Publikováno v:
Blood. 134:4664-4664
Introduction All mature T-cell-based lymphoid malignancies harbor identical (clonal) rearrangements of their T cell receptor (TCR) genes (van Dongen et al. Clinica Chimica Acta. 1991, 198, 1-92). The clonality assessment of the rearranged TCR gene is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b96382697d03f3c1b4b966f2ac300cb
https://doi.org/10.1182/blood-2019-129822
https://doi.org/10.1182/blood-2019-129822
Autor:
Tobias Herold, Maja Rothenberg-Thurley, Ulrich Mansmann, Aarif M. N. Batcha, Wolfgang E. Berdel, Maria Cristina Sauerland, Wolfgang Hiddemann, Stephanie Schneider, Stefan K. Bohlander, Hanna Janke, Jan Braess, Stefan Krebs, Helmut Blum, Julia Philippou-Massier, Bianka Ksienzyk, Stefanos A. Bamopoulos, Dennis Görlich, Karsten Spiekermann, Bernhard J. Woermann, Klaus H. Metzeler, Nikola P. Konstandin, Vindi Jurinovic
Publikováno v:
HemaSphere. 3:57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4109ba6b56fc03bc351d39e333d2cbc
https://doi.org/10.1097/01.hs9.0000559056.92553.26
https://doi.org/10.1097/01.hs9.0000559056.92553.26
Autor:
Wolfgang Hiddemann, Bernhard J. Woermann, Eva Hoster, Christian Buske, Tobias Benthaus, Stephanie Schneider, Karsten Spiekermann, Thomas Buechner, Achim Heinecke, Maria Cristina Sauerland, Friederike Schneider, Michaela Feuring-Buske, Stefan K. Bohlander, Wolfgang E. Berdel, Susanne Fritsch, Jan Braess, Evelin Zellmeier, Gudrun Mellert, Michael Unterhalt, Annika Dufour
Publikováno v:
Blood. 113:5250-5253
Mutations in the NPM1 gene represent the most frequent genetic alterations in patients with acute myeloid leukemia (AML) and are associated with a favorable outcome. In 690 normal karyotype (NK) AML patients the complete remission rates (CRs) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6c9405379e4bff9a64c979ecae1bba
https://doi.org/10.1182/blood-2008-09-172668
https://doi.org/10.1182/blood-2008-09-172668