Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bernhard H. Meurers"'
Autor:
Bernhard H. Meurers, Gustavo Dziewczapolski, Anton Bittner, Tao Shi, Fredrik Kamme, Clifford W. Shults
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 1, Pp 178-188 (2009)
Motor symptoms in Parkinson's disease (PD) are associated with complex changes of firing properties in basal ganglia output neurons (BGON). The abnormalities are generally attributed to altered synaptic input and potential post-synaptic mechanisms ar
Externí odkaz:
https://doaj.org/article/1e3e08a8d54d4a689944637062354247
Autor:
Clifford W. Shults, Fredrik Kamme, Anton Bittner, Tao Shi, Gustavo Dziewczapolski, Bernhard H. Meurers
Publikováno v:
Neurobiology of Disease, Vol 34, Iss 1, Pp 178-188 (2009)
Motor symptoms in Parkinson's disease (PD) are associated with complex changes of firing properties in basal ganglia output neurons (BGON). The abnormalities are generally attributed to altered synaptic input and potential post-synaptic mechanisms ar
Autor:
Bernhard H. Meurers, Xiao-Hong Lu, Farzad Mortazavi, X. William Yang, Victor Lo, Larry C. Ackerson, Nigel T. Maidment, Marie-Françoise Chesselet, Sheila M. Fleming, George R. Jackson, David Sulzer, Daniela Hernandez
Publikováno v:
The Journal of Neuroscience. 29:1962-1976
Recessive mutations in parkin are the most common cause of familial early-onset Parkinson's disease (PD). Recent studies suggest that certain parkin mutants may exert dominant toxic effects to cultured cells and such dominant toxicity can lead to pro
Autor:
C.D. DiCarlo, Sheila M. Fleming, Franziska Richter, Marie-Françoise Chesselet, Ronald L. Seaman, David Elashoff, Chunni Zhu, M. Oh, Pierre-Olivier Fernagut, Yen C. Hsia, Bernhard H. Meurers
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 2, Pp 182-192 (2009)
Mitochondrial complex I inhibition has been implicated in the degeneration of midbrain dopaminergic (DA) neurons in Parkinson's disease. However, the mechanisms and pathways that determine the cellular fate of DA neurons downstream of the mitochondri
Autor:
Mark G. Erlander, Xuejun Liu, Barbara Roland, Fredrik Kamme, Margot H. Bakker, Mirek Jurzak, Xiao Jun Ma, Bernhard H. Meurers, Josée E. Leysen, Ranelle C. Salunga, Hongqing Guo, Bin Tian, Anton Bittner, Pascal Bonaventure
Publikováno v:
Brain Research. 943:38-47
Information on the neuroanatomical expression of a given gene is critical to understanding its function in the central nervous system. The integration of laser capture microdissection (LCM), T7-based RNA amplification and cDNA microarrays allows for
Autor:
Anton Bittner, Giles E. Duffield, Jonathan D. Best, Jay C. Dunlap, Bernhard H. Meurers, Jennifer J. Loros
Publikováno v:
Current Biology. 12:551-557
Many aspects of physiology and behavior are temporally organized into daily 24 hr rhythms, driven by an endogenous circadian clock. Studies in eukaryotes have identified a network of interacting genes forming interlocked autoregulatory feedback loops
Autor:
Vera Medvedeva, Chunni Zhu, Bernhard H. Meurers, Marie-Françoise Chesselet, Franziska Richter
Publikováno v:
The Journal of comparative neurology. 515(5)
Hemoglobin is the oxygen carrier in vertebrate blood erythrocytes. Here we report that hemoglobin chains are expressed in mammalian brain neurons and are regulated by a mitochondrial toxin. Transcriptome analyses of laser-capture microdissected nigra
Autor:
Anton Bittner, Fredrik Kamme, Clifford W. Shults, Tao Shi, Gustavo Dziewczapolski, Bernhard H. Meurers
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(21)
Functional alterations in striatal projection neurons play a critical role in the development of motor symptoms in Parkinson's disease (PD), but their molecular adaptation to dopamine depletion remains poorly understood. In particular, type and exten