Zobrazeno 1 - 10
of 320
pro vyhledávání: '"Bernhard Fleischer"'
Autor:
Michael Petermann, Zacharias Orfanos, Julie Sellau, Mohammad Gharaibeh, Hannelore Lotter, Bernhard Fleischer, Christian Keller
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Orientia (O.) tsutsugamushi, the causative agent of scrub typhus, is a neglected, obligate intracellular bacterium that has a prominent tropism for monocytes and macrophages. Complications often involve the lung, where interstitial pneumonia is a typ
Externí odkaz:
https://doaj.org/article/59fbde9e4dc844c5bb9d432f9f2b9940
Autor:
Jessica Rauch, Jessica Barton, Marcel Kwiatkowski, Malte Wunderlich, Pascal Steffen, Kristin Moderzynski, Stefanie Papp, Katharina Höhn, Hella Schwanke, Susanne Witt, Ulricke Richardt, Ute Mehlhoop, Hartmut Schlüter, Verena Pianka, Bernhard Fleischer, Dennis Tappe, Anke Osterloh
Publikováno v:
PLoS ONE, Vol 16, Iss 6 (2021)
Rickettsioses are neglected and emerging potentially fatal febrile diseases that are caused by obligate intracellular bacteria, rickettsiae. Rickettsia (R.) typhi and R. prowazekii constitute the typhus group (TG) of rickettsiae and are the causative
Externí odkaz:
https://doaj.org/article/6ec89ed4fdab4f60a4dd6fbb67fd2814
Autor:
Kristin Moderzynski, Liza Heine, Jessica Rauch, Stefanie Papp, Svenja Kuehl, Ulricke Richardt, Bernhard Fleischer, Anke Osterloh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 2, p e0005404 (2017)
Endemic typhus caused by Rickettsia (R.) typhi is an emerging febrile disease that can be fatal due to multiple organ pathology. Here we analyzed the requirements for protection against R. typhi by T cells in the CB17 SCID model of infection. BALB/c
Externí odkaz:
https://doaj.org/article/0dc5422810c3450481b545549d3dcca8
Autor:
Richard O. Phillips, Michael Frimpong, Fred S. Sarfo, Birte Kretschmer, Marcus Beissner, Alexander Debrah, Yaw Ampem-Amoako, Kabiru M. Abass, William Thompson, Mabel Sarpong Duah, Justice Abotsi, Ohene Adjei, Bernhard Fleischer, Gisela Bretzel, Mark Wansbrough-Jones, Marc Jacobsen
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 6, Pp 1000-1003 (2014)
During August 2010–December 2012, we conducted a study of patients in Ghana who had Buruli ulcer, caused by Mycobacterium ulcerans, and found that 23% were co-infected with Mansonella perstans nematodes; 13% of controls also had M. perstans infecti
Externí odkaz:
https://doaj.org/article/3c4aeeb603e44aa692f693539a171c36
Autor:
Kristin Moderzynski, Stefanie Papp, Jessica Rauch, Liza Heine, Svenja Kuehl, Ulricke Richardt, Bernhard Fleischer, Anke Osterloh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 11, p e0005089 (2016)
Rickettsia typhi is an intracellular bacterium that causes endemic typhus, a febrile disease that can be fatal due to complications including pneumonia, hepatitis and meningoencephalitis, the latter being a regular outcome in T and B cell-deficient C
Externí odkaz:
https://doaj.org/article/e737b8127ded441bb2417d3a44abe2a2
Autor:
Matthias Hauptmann, Julia Kolbaum, Stefanie Lilla, David Wozniak, Mohammad Gharaibeh, Bernhard Fleischer, Christian A Keller
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 9, p e0004991 (2016)
T cells are known to contribute to immune protection against scrub typhus, a potentially fatal infection caused by the obligate intracellular bacterium Orientia (O.) tsutsugamushi. However, the contribution of CD8+ T cells to protection and pathogene
Externí odkaz:
https://doaj.org/article/eb7d45588d714ab3ab8cc9d8e5bfa358
Autor:
Stefanie Papp, Kristin Moderzynski, Jessica Rauch, Liza Heine, Svenja Kuehl, Ulricke Richardt, Heidelinde Mueller, Bernhard Fleischer, Anke Osterloh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 8, p e0004935 (2016)
Rickettsia (R.) typhi is the causative agent of endemic typhus, an emerging febrile disease that is associated with complications such as pneumonia, encephalitis and liver dysfunction. To elucidate how innate immune mechanisms contribute to defense a
Externí odkaz:
https://doaj.org/article/4d62bb1a66aa45e6985f7acb4c1dca3e
Autor:
Richard Odame Phillips, Delphin Mavinga Phanzu, Marcus Beissner, Kossi Badziklou, Elysée Kalundieko Luzolo, Fred Stephen Sarfo, Wemboo Afiwa Halatoko, Yaw Amoako, Michael Frimpong, Abass Mohammed Kabiru, Ebekalisai Piten, Issaka Maman, Bawimodom Bidjada, Adjaho Koba, Koffi Somenou Awoussi, Basile Kobara, Jörg Nitschke, Franz Xaver Wiedemann, Abiba Banla Kere, Ohene Adjei, Thomas Löscher, Bernhard Fleischer, Gisela Bretzel, Karl-Heinz Herbinger
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 1, p e3457 (2015)
The only available vaccine that could be potentially beneficial against mycobacterial diseases contains live attenuated bovine tuberculosis bacillus (Mycobacterium bovis) also called Bacillus Calmette-Guérin (BCG). Even though the BCG vaccine is sti
Externí odkaz:
https://doaj.org/article/611e70905af648808a6a17f41ea4dba9
Autor:
Christian A Keller, Matthias Hauptmann, Julia Kolbaum, Mohammad Gharaibeh, Melanie Neumann, Markus Glatzel, Bernhard Fleischer
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 8, p e3064 (2014)
Central aspects in the pathogenesis of scrub typhus, an infection caused by Orientia (O.) tsutsugamushi, have remained obscure. Its organ and cellular tropism are poorly understood. The purpose of this study was to analyze the kinetics of bacterial d
Externí odkaz:
https://doaj.org/article/4105ce815bec4765a5dc0909e336f36b
Autor:
Maria del Rosario Espinoza Mora, Christiane Steeg, Susanne Tartz, Volker Heussler, Tim Sparwasser, Andreas Link, Bernhard Fleischer, Thomas Jacobs
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104627 (2014)
Regulatory T cells (T(reg)) have been shown to restrict vaccine-induced T cell responses in different experimental models. In these studies CD4(+)CD25(+) T(reg) were depleted using monoclonal antibodies against CD25, which might also interfere with C
Externí odkaz:
https://doaj.org/article/a926a14758a24321b0cc7091a0566c6f