Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bernhard F. Gillissen"'
Autor:
Sandra Weller, Astrid Toennießen, Benjamin Schaefer, Tobias Beigl, Alina Muenchow, Kathrin Böpple, Ute Hofmann, Bernhard F. Gillissen, Walter E. Aulitzky, Hans-Georg Kopp, Frank Essmann
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Enhanced expression of anti-apoptotic B-cell lymphoma 2 (BCL-2) protein is frequent in cancer. Targeting of BCL-2 with the specific inhibitor ABT-199 (Venetoclax) has significant clinical activity in malignant diseases such as chronic lympho
Externí odkaz:
https://doaj.org/article/25b403ed7a8d4d12935b61caf6d80df9
Autor:
Stephanie Einsele-Scholz, Silke Malmsheimer, Katrin Bertram, Daniel Stehle, Janina Johänning, Marianne Manz, Peter T. Daniel, Bernhard F. Gillissen, Klaus Schulze-Osthoff, Frank Essmann
Publikováno v:
Journal of cell science. 129(11)
The pro-apoptotic multidomain Bcl-2 proteins Bax and Bak (also known as BAK1) are considered the gatekeepers of the intrinsic pathway of apoptosis by triggering the mitochondrial release of cytochrome c The role of the third Bax- and Bak-homologous m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec9adeb9bbe6429c4c0c5223110c080
https://pubmed.ncbi.nlm.nih.gov/27505430
https://pubmed.ncbi.nlm.nih.gov/27505430