Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bernd Werle"'
Autor:
Tomaz Langerholc, Rastko Golouh, Vito Turk, Bernd Werle, Boris Turk, Matjaz Jeras, Urska Repnik, Valentina Zavasnik Bergant, Aleš Premzl, Janko Kos, Andreja Sekirnik
Publikováno v:
Experimental Cell Research. 306:103-113
Cathepsin X, a recently discovered lysosomal cysteine protease, shares common structural features and activity properties with cysteine protease cathepsin B. Based on its widespread mRNA distribution in primary tumors and tumor cell lines, a redundan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5d79a0f7d943b988917047e904c50e
https://doi.org/10.1016/j.yexcr.2004.12.006
https://doi.org/10.1016/j.yexcr.2004.12.006
Autor:
Vladimir A Bezmen, Alexander V. Timoshenko, Olga V. Maslakova, Viktor Ya Rebeko, Klaus Kayser, Bernd Werle
Publikováno v:
Cancer Letters. 182:93-99
To assess whether cancer-induced pleurisy is associated with an alteration of nitric oxide (NO)-synthase activity, the levels of nitrate/nitrite (NOx) were measured in blood serum (BS) and pleural effusion (PE) of 35 cancer patients (secondary pleura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528195a661472eedc53fef0147ea5601
https://doi.org/10.1016/s0304-3835(02)00063-0
https://doi.org/10.1016/s0304-3835(02)00063-0
Publikováno v:
British Journal of Cancer
In order to evaluate the role of cysteine peptidase cathepsin H (Cath H) in human lung cancer its protein levels were determined in 148 pairs of lung tumour tissue and adjacent non-tumourous lung parenchyma using the enzyme-linked immunosorbent assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a823b07c27ef94af6282824efe97b7
https://doi.org/10.1054/bjoc.1999.0999
https://doi.org/10.1054/bjoc.1999.0999
Autor:
Bernd Werle, T T Lah, H Lötterle, U Schanzenbächer, M Kras̆ovec, H Bülzebruck, J. Schirren, E Kalman, Janko Kos, Eberhard Spiess, Klaus Kayser
Publikováno v:
British Journal of Cancer
In order to evaluate the possible role of the proteolytic enzyme cathepsin B (cath B) in human non-small cell lung cancer (NSCLC) we examined cath B concentrations (cath Bc) and activities (cath BA) in homogenates of 127 pairs of lung tumour tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4558e5958e16e31e24e27a8091c9ba38
https://doi.org/10.1038/sj.bjc.6690723
https://doi.org/10.1038/sj.bjc.6690723
Publikováno v:
International journal of oncology. 5(1)
In the study of 69 matched pairs of lung tumors and normal lung parenchyma, the median activities of cathepsin B (CB) and cystein proteinase inhibitors (CPI's) in tumors were found to be increased 4.4-fold and twofold, respectively. The levels of CB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c77c862e874c242008d96d3c0ed1779
https://pubmed.ncbi.nlm.nih.gov/21559560
https://pubmed.ncbi.nlm.nih.gov/21559560
Autor:
Klaus Kayser, Eberhard Spiess, Britta Jülke, Bernd Werle, Eileen Ebert, Tamara T. Lah, Werner Ebert, Ulrike Schanzenbächer, Werner Fiehn, Janko Kos, Magnus Abrahamson
Publikováno v:
Oncology Reports.
Cystatins regulate tumour-associated cysteine proteases, however, their role in tumour progression is not clear yet. To assess their relevance in the progression of non-small cell lung cancer (NSCLC) the protein level, cysteine protease activity (CPI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4311796de89bb9bb1898e3640a1cf228
https://doi.org/10.3892/or.16.4.647
https://doi.org/10.3892/or.16.4.647
Publikováno v:
Anticancer research. 23(3C)
To immunohistochemically investigate the expression of cathepsin B and cathepsin L in various lung cancer cell types in association with the patients' prognosis.Histological slides obtained from formalin-fixed, paraffin-embedded tissue of 120 potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71828c1cc44f4eba723bcffaf5dd266d
https://pubmed.ncbi.nlm.nih.gov/12926111
https://pubmed.ncbi.nlm.nih.gov/12926111
Autor:
Kirsten Sauckel, Bernd Werle, Magnus Abrahamson, Maria Bjarnadottir, Werner Ebert, Carl-Michael Nathanson, Eberhard Spiess
Publikováno v:
Biological chemistry. 384(2)
Secretory type 2 cystatins, like cystatins C, E/M and F, are thought to be involved in many pathobiological processes, including vascular amyloidosis, rheumatoid arthritis, Alzheimers disease, osteoporosis, viral and bacterial infections, inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2983c84110bd95f9c006547535d4d818
https://pubmed.ncbi.nlm.nih.gov/12675521
https://pubmed.ncbi.nlm.nih.gov/12675521
Autor:
Irena Zore, Marta Krasovec, Nina Cimerman, Robert Kuhelj, Bernd Werle, Hans Jorgen Nielsen, Nils Brünner, Janko Kos
Publikováno v:
Biological chemistry. 382(5)
A sandwich-type ELISA has been developed for quantification of the complex between the cysteine proteinase cathepsin B (CB) and its reversible tight-binding inhibitor cystatin C (CC) in normal and pathological sera. The assay is based on a combinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93da8ad3fa22fa5b11981d103ff55746
https://pubmed.ncbi.nlm.nih.gov/11517934
https://pubmed.ncbi.nlm.nih.gov/11517934
Autor:
Clemens Kraft, Klaus Kayser, Bernd Werle, Werner Ebert, Ulrike Schanzenbächer, Janko Kos, Tamara T. Lah, Eberhard Spiess
Publikováno v:
Cancer. 89(11)
BACKGROUND Tumor cells require specific proteolytic enzymes for invasion and metastasis, including lysosomal peptidases—cathepsins. Cathepsin B is a lysosomal cysteine peptidase, which appears to play a major role in invasion and metastasis of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36bc8edb84c2c0f8e9b4c70b70fe9f7
https://pubmed.ncbi.nlm.nih.gov/11147599
https://pubmed.ncbi.nlm.nih.gov/11147599