Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bernd W Kalisch"'
Publikováno v:
Biopolymers. 72:490-499
The vibrational circular dichroism (VCD) and IR absorption spectra of a dodecamer d(CCTCTGGTCTCC)·d(GGAGACCAGAGG) coordinated with cisplatin are distinct compared to those of the dodecamer without cisplatin. Although the intensity of PO2/deoxyribose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c988940348b01eb1abb89603076e561
https://doi.org/10.1002/bip.10478
https://doi.org/10.1002/bip.10478
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:493-499
We employ NMR structure determination, thermodynamics, and enzymatics to uncover the structural, thermodynamic and enzymatic properties of alpha/beta-ODNs containing 3'-3' and 5'-5' linkages. RNase H studies show that alpha/beta-gapmers that are desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b60d0e3fb328cb7241cb81f5538de4c
https://doi.org/10.1081/ncn-100002324
https://doi.org/10.1081/ncn-100002324
Publikováno v:
FEBS Letters. 427:301-304
Alternating polypurine d(GA)n, sequences exhibit a considerable polymorphism. Here we report that alpha d(GA) x d(GA) sequences form an antiparallel stranded duplex DNA at neutral pH. The spectroscopic, electrophoretic and thermodynamic properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4617d00839bbd73751a12d6c2ba987c
https://doi.org/10.1016/s0014-5793(98)00453-0
https://doi.org/10.1016/s0014-5793(98)00453-0
Publikováno v:
Biochemistry and Cell Biology. 76:391-402
We have correlated the structural perturbations caused by DNA mismatches with the enzymatic data of the interaction of the restriction endonuclease EcoRI with DNA. Oligonucleotides d(CGAGAATTCTCA5GAXAATTCT) (X = G, A, T) and d(CGCGAATTYGCGT4CGCXAATTC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75518fb3d1834f33f9ec9ac388b145e7
https://doi.org/10.1139/o98-031
https://doi.org/10.1139/o98-031
Publikováno v:
Biochemistry and Cell Biology. 76:391-402
We have correlated the structural perturbations caused by DNA mismatches with the enzymatic data of the interaction of the restriction endonuclease EcoRI with DNA. Oligonucleotides d(CGAGAATTCTCA5GAXAATTCT) (X = G, A, T) and d(CGCGAATTYGCGT4CGCXAATTC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f8828f238508e64077491543fafab89
https://doi.org/10.1139/bcb-76-2-3-391
https://doi.org/10.1139/bcb-76-2-3-391
Autor:
Markus W. Gerrnann, Richard T. Pon, James M. Aramini, Johan H. van de Sande, Bernd W. Kalisch
Publikováno v:
Nucleosides and Nucleotides. 16:1481-1485
Oligodeoxynucleotides that possess alpha anomeric nucleotides and polarity reversals show promise for application in the area of antisense therapy. Here we provide a survey of the spectroscopic, thermodynamic, and enzymatic techniques used in our lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb15caf1da99ea1223d4e580e55c86b
https://doi.org/10.1080/07328319708006211
https://doi.org/10.1080/07328319708006211
Publikováno v:
Biochemistry. 37(37)
Alternating polypurine sequences exhibit remarkable polymorphism. In this study, we report that dGA.dGT sequences form parallel stranded duplex DNA at neutral pH. Using two model hairpins, 3'-d(GT)3-5'5'-T4(AG)3-3' (I) and 3'-d(GT)4-5'5'-T4(AG)4-3' (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03148adf1e46172dce76e353ec990c5
https://pubmed.ncbi.nlm.nih.gov/9737876
https://pubmed.ncbi.nlm.nih.gov/9737876
Publikováno v:
Antisensenucleic acid drug development. 8(2)
Human papillomavirus (HPV) type 16 E6 and E7 inactivate the tumor suppressors p53 and pRB, respectively. Both viral oncoproteins play important roles in maintaining the transformed phenotype of cells. In this study, we examine the effects of antisens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427effc4229e71e342e25cecd33a9569
https://pubmed.ncbi.nlm.nih.gov/9593047
https://pubmed.ncbi.nlm.nih.gov/9593047
Publikováno v:
Biochemistry. 29(40)
Parallel-stranded DNA can be formed from alternating AT segments and is not restricted exclusively to homooligomeric AT sequences. DNA oligonucleotides 3'-d(AT)nxC4(AT)n-3' (where x indicates the location of the 5'-5' phosphodiester linkage) form par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f3547134a0e164204ef05c4ab4f31c
https://pubmed.ncbi.nlm.nih.gov/2248956
https://pubmed.ncbi.nlm.nih.gov/2248956
Publikováno v:
Nucleic acids research. 18(6)
We have investigated loop-induced structural perturbation of the stem structure in hairpins d(GAATTCXnGAATTC) (X = A, T and n = 3, 4, 5 and 6) that contain an EcoRI restriction site in close proximity to the hairpin loop. Oligonucleotides containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f71999eb63458ea7a85f9e5f566dfa9
https://pubmed.ncbi.nlm.nih.gov/2326190
https://pubmed.ncbi.nlm.nih.gov/2326190