Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Bernd W, Spur"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
In severe bacterial infections, there is a pro-inflammatory response to promote bacterial clearance but this response can cause tissue injury. Later, the immune system becomes dysregulated and the host is unable to clear a secondary or a pre-existing
Externí odkaz:
https://doaj.org/article/25bcdb6a15df4fd89a3dc424a21c8b88
Autor:
Kimberly Pistorius, Lucy Ly, Patricia R. Souza, Esteban A. Gomez, Duco S. Koenis, Ana R. Rodriguez, Julie Foster, Jane Sosabowski, Mark Hopkinson, Vinothini Rajeeve, Bernd W. Spur, Andrew Pitsillides, Costantino Pitzalis, Jesmond Dalli
Publikováno v:
EBioMedicine, Vol 79, Iss , Pp 103974- (2022)
Summary: Background: Rheumatoid arthritis (RA) is a progressive degenerative disorder that leads to joint destruction. Available treatments only target the inflammatory component with minimal impact on joint repair. We recently uncovered a previously
Externí odkaz:
https://doaj.org/article/b2ce0d97eb95459798637594025cd17b
Autor:
Robert Nshimiyimana, Stephania Libreros, Mélissa Simard, Nan Chiang, Ana R. Rodriguez, Bernd W. Spur, Jesper Z. Haeggström, Charles N. Serhan
Publikováno v:
American Journal of Hematology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb996c820b2e7f3a0bb7b379ca3a0d18
https://doi.org/10.1002/ajh.26932
https://doi.org/10.1002/ajh.26932
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149319 (2016)
Maresin conjugates in tissue regeneration (MCTR) are a new family of evolutionarily conserved chemical signals that orchestrate host responses to promote tissue regeneration and resolution of infections. Herein, we identified the novel MCTR3 and esta
Externí odkaz:
https://doaj.org/article/46d11f1daceb43d58b8c3811f820afd7
Publikováno v:
Blood
The newly identified 13-series (T-series) resolvins (RvTs) regulate phagocyte functions and accelerate resolution of infectious inflammation. Because severe acute respiratory syndrome coronavirus 2 elicits uncontrolled inflammation involving neutroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f703db4ccc03c2e7af9a6b741b8ee5
http://europepmc.org/articles/PMC8612755
http://europepmc.org/articles/PMC8612755
Autor:
Kimberly Pistorius, Lucy Ly, Patricia R. Souza, Esteban A. Gomez, Duco S. Koenis, Ana R. Rodriguez, Julie Foster, Jane Sosabowski, Mark Hopkinson, Vinothini Rajeeve, Bernd W. Spur, Andrew Pitsillides, Costantino Pitzalis, Jesmond Dalli
Publikováno v:
EBioMedicine. 79
Rheumatoid arthritis (RA) is a progressive degenerative disorder that leads to joint destruction. Available treatments only target the inflammatory component with minimal impact on joint repair. We recently uncovered a previously unappreciated family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2dd074049f24598e86012c8fb98c207
https://pubmed.ncbi.nlm.nih.gov/35430453
https://pubmed.ncbi.nlm.nih.gov/35430453
Autor:
Ana R. Rodriguez, P.Y. Kadiyam Sundarasivarao, Kingsley Yin, J.M. Thornton, Jean Walker, Bernd W. Spur
Publikováno v:
Prostaglandins Other Lipid Mediat
Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic bacterium commonly found in wound infections and airways of cystic fibrosis patients. P. aeruginosa readily forms biofilms which can reduce the efficacy of antibiotics used to eradicate the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4848b37ba39eb6b847a5430521809267
https://europepmc.org/articles/PMC7856039/
https://europepmc.org/articles/PMC7856039/
Autor:
Ana R, Rodriguez, Bernd W, Spur
Publikováno v:
Tetrahedron Lett
The first total synthesis of the pro-resolving lipid mediator 7(S),12(R),13(S)-Resolvin T2 [7(S), 12(R), 13(S)-RvT2] and its 13(R)-epimer, derived from n-3 docosapentaenoic acid (n-3 DPA), are described. 7(S), 12(R), 13(S)-RvT2 and its 13(R)-epimer w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53f42ec0472c051399f97e909faa6992
https://pubmed.ncbi.nlm.nih.gov/32863450
https://pubmed.ncbi.nlm.nih.gov/32863450
Autor:
Ana R. Rodriguez, Paul C. Norris, Bernd W. Spur, Xavier de la Rosa, Nan Chiang, Charles N. Serhan
Publikováno v:
The American Journal of Pathology. 188:950-966
Resolvin conjugates in tissue regeneration (RCTRs) are new chemical signals that accelerate resolution of inflammation, infection, and tissue regeneration. Herein, using liquid chromatography–tandem mass spectrometry–based metabololipidomics, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8666e06a48f743ed1fae630da6c4b295
https://doi.org/10.1016/j.ajpath.2018.01.004
https://doi.org/10.1016/j.ajpath.2018.01.004
Autor:
Bernd W. Spur, Ana R. Rodriguez
Publikováno v:
Tetrahedron Letters. 59:1143-1146
The first total synthesis of the anti-inflammatory and pro-resolving lipid mediator 16(R),17(S)-diHDHA, derived from docosahexaenoic acid (DHA), and its 16-epimer have been achieved. Two synthetic approaches are described for the synthesis of 16(R),1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ba1d6c90ef5593242dd604662f066d
https://doi.org/10.1016/j.tetlet.2018.02.029
https://doi.org/10.1016/j.tetlet.2018.02.029