Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum

Autor: Michel Rivoire, Fleur Chapus, Audrey Diederichs, Antoine Alam, Laurent Fraisse, Kara Carter, Barbara Testoni, Bernd Stadelmayer, Fabien Zoulim, Gregory Neveu

Publikováno v: Journal of Hepatology
Journal of Hepatology, Elsevier, 2020, 73, pp.40-51. ⟨10.1016/j.jhep.2020.01.028⟩

Background & Aims Covalently closed circular DNA (cccDNA) is the episomal form of the HBV genome that stably resides in the nucleus of infected hepatocytes. cccDNA is the template for the transcription of 6 major viral RNAs, i.e. preC, pg, preS1/2, S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40503f626b927b465b61404951e3619
https://hal.archives-ouvertes.fr/hal-03490308

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes

Autor: Monsef Benkirane, Slavik Koval, Gaël Micas, Nathalie Malirat, Raoul Raffel, Pascal G.P. Martin, Bernd Stadelmayer, Dany Severac, Hugues Parrinello, Bijan Sobhian, Olivier Cuvier, Adrien Gamot, Stéphanie Rialle

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5, pp.5531
Nature Communications, Nature Publishing Group, 2014, 5, pp.5531. ⟨10.1038/ncomms6531⟩
Nature Communications, 2014, 5, pp.5531. ⟨10.1038/ncomms6531⟩
Nature Communications (5), . (2014)

RNA polymerase II (RNAPII) pausing/termination shortly after initiation is a hallmark of gene regulation. Here, we show that negative elongation factor (NELF) interacts with Integrator complex subunits (INTScom), RNAPII and Spt5. The interaction betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a59385fb97d405061b155ff80c08a0
https://hal.archives-ouvertes.fr/hal-01101245

Rôle des hélicases à motif DEAD DDX5 et DDX17 dans la maturation des ARN du Virus de l'Hépatite B

Autor: Chapus, Fleur

Publikováno v: Virology. Université de Lyon, 2020. English. ⟨NNT : 2020LYSE1098⟩

Role of the DEAD-box helicases DDX5 and DDX17 in HBV transcriptional regulation and RNA processingChronicity of hepatitis B virus (HBV) infection hinges on the persistence of covalently-closed-circular DNA (cccDNA) in the nucleus of infected hepatocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2592::12e3bd680b8619cd58d9658b6c1ecad5
https://tel.archives-ouvertes.fr/tel-03168041

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes.

Autor: Stadelmayer, Bernd, Micas, Gaël, Gamot, Adrien, Martin, Pascal, Malirat, Nathalie, Koval, Slavik, Raffel, Raoul, Sobhian, Bijan, Severac, Dany, Rialle, Stéphanie, Parrinello, Hugues, Cuvier, Olivier, Benkirane, Monsef

Publikováno v: Nature Communications; Nov2014, Vol. 5 Issue 11, p5531, 1p