Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Bernd Seilheimer"'
Autor:
Ludger Gerdesmeyer, Johannes Vester, Christian Schneider, Britt Wildemann, Christine Frank, Myron Schultz, Bernd Seilheimer, Alta Smit, Gino Kerkhoffs
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 3, p 841 (2024)
Background: Topical NSAIDs are widely used to treat ankle sprains. Traumed (Tr14) gel is a multicomponent formulation, demonstrating inflammation-resolution properties. Methods: This multicenter, double-blind trial investigated the efficacy and safet
Externí odkaz:
https://doaj.org/article/497e3ab7cf774d24bf58af54adf9b32a
Autor:
Kerstin Ott, Taneli Heikkinen, Kimmo K. Lehtimäki, Kaisa Paldanius, Jukka Puoliväli, Raimo Pussinen, Emile Andriambeloson, Bertrand Huyard, Stéphanie Wagner, Cathrin Schnack, Anke Wahler, Bjoern von Einem, Christine A. F. von Arnim, Yvonne Burmeister, Kathrin Weyer, Bernd Seilheimer
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionCognitive impairment associated with old age or various brain disorders may be very disabling for affected individuals, placing their carers and public health services under considerable stress. The standard-of-care drugs produce only tra
Externí odkaz:
https://doaj.org/article/f12ba6f9b38b48368ec02d6e6c2f5b15
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3216 (2023)
Metabolic dysfunction-associated steatotic liver disease (MASLD)—formerly known as non-alcoholic fatty liver disease (NAFLD)—is the most common chronic liver disease worldwide. Since there is currently no approved pharmacotherapy for MASLD, there
Externí odkaz:
https://doaj.org/article/a4e56f1d3a234288a5f46ccba90895bb
Autor:
Georges St. Laurent, Ian Toma, Bernd Seilheimer, Konstantin Cesnulevicius, Myron Schultz, Michael Tackett, Jianhua Zhou, Maxim Ri, Dmitry Shtokalo, Denis Antonets, Tisha Jepson, Timothy A. McCaffrey
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Despite proven therapeutic effects in inflammatory conditions, the specific mechanisms of phytochemical therapies are not well understood. The transcriptome effects of Traumeel (Tr14), a multicomponent natural product, and diclofe
Externí odkaz:
https://doaj.org/article/c8303c41583743ea9e38e98bb0993bb8
Autor:
Bérénice Hatat, Romain Boularand, Claire Bringuier, Nicolas Chanut, Stéphane Besnard, Andrea M. Mueller, Kathrin Weyer, Bernd Seilheimer, Brahim Tighilet, Christian Chabbert
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
The aim of this study was to assess the effect of Vertigoheel on central vestibular compensation and cognitive deficits in rats subjected to peripheral vestibular loss. Young adult male Long Evans rats were subjected to bilateral vestibular insults t
Externí odkaz:
https://doaj.org/article/ca055698e3bb418c9246be7c8d38bfe5
Autor:
Christelle Sanchez, Kathrin Hemmer, Natascha Krömmelbein, Bernd Seilheimer, Jean-Emile Dubuc, Christophe Antoine, Yves Henrotin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Objectives: Zeel T (Ze14) is a multicomponent medicinal product. Initial preclinical data suggested a preventive effect on cartilage degradation. Clinical observational studies demonstrated that Ze14 reduced symptoms of osteoarthritis (OA), including
Externí odkaz:
https://doaj.org/article/012742e11f324e9a8d5850207f66acc7
Autor:
Andrea M. Mueller, Robert Kleemann, Eveline Gart, Wim van Duyvenvoorde, Lars Verschuren, Martien Caspers, Aswin Menke, Natascha Krömmelbein, Kanita Salic, Yvonne Burmeister, Bernd Seilheimer, Martine C. Morrison
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundNon-alcoholic fatty liver disease (NAFLD) is a complex multifactorial disorder that is characterised by dysfunctional lipid metabolism and cholesterol homeostasis, and a related chronic inflammatory response. NAFLD has become the most commo
Externí odkaz:
https://doaj.org/article/fd0f49bca8f34e1ba51bb91bc30b7b07
Autor:
Paul M. Jordan, Emeline van Goethem, Andrea M. Müller, Kathrin Hemmer, Virginie Gavioli, Vincent Baillif, Yvonne Burmeister, Natascha Krömmelbein, Marc Dubourdeau, Bernd Seilheimer, Oliver Werz
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1123 (2021)
The resolution of inflammation is an integral part of the acute inflammatory response and eventually leads to the return to homeostasis. It is supported by specialized pro-resolving mediators (SPMs) that act as immunoresolvents via specific G-protein
Externí odkaz:
https://doaj.org/article/55f1d332c147488e8241f5eb2dfdd6dc
Autor:
Sabine Wronski, Julia Dannenmaier, Sabine Schild, Olaf Macke, Laura Müller, Yvonne Burmeister, Bernd Seilheimer, Meike Müller
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195822 (2018)
Respiratory viruses such as respiratory syncytial virus (RSV) or rhinovirus are one of the major causes for respiratory tract infections causing common cold disease. Respiratory viral infections range from mild symptoms in adults to serious illness e
Externí odkaz:
https://doaj.org/article/09220373b7054ec4888313c0c97a4ccb
Autor:
Georges St. Laurent, Bernd Seilheimer, Michael Tackett, Jianhua Zhou, Dmitry Shtokalo, Yuri Vyatkin, Maxim Ri, Ian Toma, Dan Jones, Timothy A. McCaffrey
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2017)
Wound healing involves an orchestrated response that engages multiple processes, such as hemostasis, cellular migration, extracellular matrix synthesis, and in particular, inflammation. Using a murine model of cutaneous wound repair, the transcriptom
Externí odkaz:
https://doaj.org/article/f7ade1a0da4845e39068f8d5d0274f1e