Regulation by vitamin E of the scavenger receptor BI in rat liver and HepG2 cells

Autor: Wolfgang Witt, Ingrid Kolleck, Henry Fechner, Pranav Sinha, Bernd Rüstow

Publikováno v: Journal of Lipid Research, Vol 41, Iss 12, Pp 2009-2016 (2000)

The scavenger receptor class B type I (SR-BI) mediates the selective uptake of cholesterol and cholesteryl ester (CE) from high density lipoprotein (HDL) into cells. The high expression in liver and steroidogenic tissues is compatible with a role of

Externí odkaz: https://doaj.org/article/47d291b8a81f40359043e2fba0a4f17e

Activation of PPARγ reverses a defect of surfactant synthesis in mice lacking two types of fatty acid binding protein

Autor: Yuji Owada, Bernd Rüstow, Christian Schachtrup, Hans-Joachim Galla, Burkhard Lachmann, Bert Binas, Hisatake Kondo, Stefan Malcharek, Friedrich Spener, Jack J. Haitsma

Publikováno v: Schachtrup, C, Malcharek, S, Haitsma, J J, Lachmann, B, Owada, Y, Binas, B, Kondo, H, Rüstow, B, Galla, H J & Spener, F 2008, ' Activation of PPARγ reverses a defect of surfactant synthesis in mice lacking two types of fatty acid binding protein ', Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, vol. 1781, no. 6-7, pp. 314-320 . https://doi.org/10.1016/j.bbalip.2008.04.010
Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1781(6-7), 314-320. Elsevier

Lung surfactant is a lipid-protein-film covering the inner alveolar surface. We have previously shown that double knock-out (d-ko) mice lacking both the epidermal-type (E-) and the heart-type (H-) fatty acid binding protein (FABP) exhibit a defect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38b1d14d0cac27f043f7fd811d8ecfb9
https://doi.org/10.1016/j.bbalip.2008.04.010

Vitamin E differentially regulates the expression of peroxiredoxin-1 and -6 in alveolar type II cells

Autor: Michael Schlame, Angelika Tölle, Florian Guthmann, Bernd Rüstow, Nico Charlier

Publikováno v: Free Radical Biology and Medicine. 38:1401-1408

Vitamin E is the primary lipophilic antioxidant in mammals. Lack of vitamin E may lead to an increase of cytotoxic phospholipid-peroxidation products (PL-Ox). However, we could previously show that alimentary vitamin E-depletion in rats did not chang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b154e43b84356c4b5a90dd6e293a6179
https://doi.org/10.1016/j.freeradbiomed.2005.02.001

Vitamin E deficiency reduces surfactant lipid biosynthesis in alveolar type II cells

Autor: Michael Schlame, Florian Guthmann, Bernd Rüstow, Christian Schachtrup, Ingrid Kolleck, Friedrich Spener

Publikováno v: Free Radical Biology and Medicine. 34:663-673

Reactive oxygen species play an important role in development of lung injury. Neonates exhibit a high risk of developing acute and/or chronic lung disorder, often associated with surfactant deficiency, and in parallel they show low vitamin E concentr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8c85061b8dc273770f96e2a737e640
https://doi.org/10.1016/s0891-5849(02)01376-x

Bioactive Oxidized Lipids in the Plasma of Cardiac Surgical Intensive Care Patients

Autor: Wolfgang J. Kox, Hartmut Kern, Wolfram Johnen, Renate Haupt, Bernd Rüstow, Michael Schlame, Bettina Frey

Publikováno v: Shock. 18:14-17

Critical illness is associated with increased oxidative stress that may give rise to the formation of lipid hydroperoxides (LOOH) and various secondary degradation products such as fragmented phosphatidylcholine (FPC) and lipids related to the platel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf48fbc0477198f02619307654244f8
https://doi.org/10.1097/00024382-200207000-00003