Výsledky vyhledávání - "Bernd Nöding"

Helical Superstructure of Intermediate Filaments

Autor: Martin Michael Müller, Igor M. Kulić, Hervé Mohrbach, Sarah Köster, René Messina, Lila Bouzar, Bernd Nöding

Publikováno v: Physical Review Letters
Physical Review Letters, American Physical Society, 2019, 122 (9), ⟨10.1103/PhysRevLett.122.098101⟩
Physical Review Letters, 2019, 122 (9), ⟨10.1103/PhysRevLett.122.098101⟩

Intermediate filaments are the least explored among the large cytoskeletal elements. We show here that they display conformational anomalies in narrow microfluidic channels. Their unusual behavior can be understood as the consequence of a previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dcac4a03f65852373fac9a4d47fe24
https://pubmed.ncbi.nlm.nih.gov/30932552

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Detection of contactin-2 in cerebrospinal fluid (CSF) of patients with Alzheimer's disease using Fluorescence Correlation Spectroscopy (FCS)

Autor: Detlev Schild, Charlotte E. Teunissen, Wiesje M. van der Flier, Marleen J.A. Koel-Simmelink, Bernd Nöding, Madhurima Chatterjee, Eline A.J. Willemse

Publikováno v: Chatterjee, M, Nöding, B, Willemse, E A J, Koel-Simmelink, M J A, van der Flier, W M, Schild, D & Teunissen, C E 2017, ' Detection of contactin-2 in cerebrospinal fluid (CSF) of patients with Alzheimer's disease using Fluorescence Correlation Spectroscopy (FCS) ', Clinical Biochemistry, vol. 50, no. 18, pp. 1061-1066 . https://doi.org/10.1016/j.clinbiochem.2017.08.017
Clinical Biochemistry, 50(18), 1061-1066. Elsevier Inc.

Objectives Alzheimer's disease (AD) is the most common cause of dementia in the world. As many AD biomarkers occur at rather low abundances in CSF or blood, techniques of very high sensitivity and accuracy are important as diagnostic tools in the cli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548d03c7263e97aff2ee464c2632456b
https://research.vumc.nl/en/publications/cc397315-3eb4-4286-9dc4-b84cd72bb595

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Direct Observation of Subunit Exchange along Mature Vimentin Intermediate Filaments

Autor: Sarah Köster, Bernd Nöding, Harald Herrmann

Publikováno v: Biophysical Journal. 107:2923-2931

Actin filaments, microtubules, and intermediate filaments (IFs) are central elements of the metazoan cytoskeleton. At the molecular level, the assembly mechanism for actin filaments and microtubules is fundamentally different from that of IFs. The fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c5e4372a41f2a17bdf7bf3de292fb4
https://doi.org/10.1016/j.bpj.2014.09.050

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Dynamics of intermediate filament assembly followed in micro-flow by small angle X-ray scattering

Autor: Martha Brennich, Jens-Friedrich Nolting, Thomas Pfohl, Susanne Bauch, Bernd Nöding, Harald Herrmann, Christian Dammann, Sarah Köster

Publikováno v: Lab on a chip

The assembly of intermediate filaments (IFs) is a complex process that can be recapitulated through a series of distinct steps in vitro. The combination of microfluidics and small angle X-ray scattering (SAXS) provides a powerful tool to investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b0ec290430e4a4f859c5dcb29be668

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Intermediate filaments in small configuration spaces

Autor: Sarah Köster, Bernd Nöding

Publikováno v: Physical review letters. 108(8)

Intermediate filaments play a key role in cell mechanics. Apart from their great importance from a biomedical point of view, they also act as a very suitable micrometer-sized model system for semiflexible polymers. We perform a statistical analysis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc7015380a6fe06907ba14402bed482
https://pubmed.ncbi.nlm.nih.gov/22463576

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Vimentin networks at tunable ion-concentration in microfluidic drops

Autor: Bernd Nöding, Sarah Köster, Christian Dammann

Publikováno v: Biomicrofluidics. 6:022009

The structure and function of biological systems, for example, cells and proteins, depend strongly on their chemical environment. To investigate such dependence, we design a polydimethylsiloxane-based microfluidic device to encapsulate biological sys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b49c54666df319d9c4ecc89c44bbf07
https://doi.org/10.1063/1.4705103

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